Zobrazeno 1 - 10
of 13 223
pro vyhledávání: '"alpha-glucosidase"'
Publikováno v:
罕见病研究, Vol 3, Iss 3, Pp 318-325 (2024)
ObjectiveTo investigate the clinical features and genetic characteristics of patients with late-onset Pompe disease(LOPD).MethodsA total of 13 patients diagnosed with LOPD in the First Affiliated Hospital of Zhejiang University School of Medicine fro
Externí odkaz:
https://doaj.org/article/7487c38618fc40b497f84eab5aefc6b0
Autor:
Sandra Milena Castellar-Leones, Fernando Ortiz-Corredor, Daniel Manrique-Hernández, Diana Sánchez-Peñarete, Edicson Ruiz-Ospina, Diana Soto-Peña, Cristian Correa-Arrieta
Publikováno v:
Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-5 (2024)
Abstract Background Pompe disease, a rare autosomal recessive disorder caused by acid alpha-glucosidase deficiency, results in progressive glycogen accumulation and multisystem dysfunction. Enzyme replacement therapy with recombinant human acid alpha
Externí odkaz:
https://doaj.org/article/dea8e376910644618a67679fbc33812e
Autor:
Niels B Dalsgaard, Lærke S Gasbjerg, Laura S Hansen, Dennis S Nielsen, Torben S Rasmussen, Filip K Knop
Publikováno v:
Endocrine Connections, Vol 13, Iss 7, Pp 1-7 (2024)
Aim: The alpha-glucosidase inhibitor acarbose is approved for the treatment of type 2 diabetes (T2D). It acts in the lumen of the gut by reducing intestinal hydrolysis and absorption of ingested carbohydrates. This reduces postprandial blood glucose
Externí odkaz:
https://doaj.org/article/fc39470700c2487790ef240db845be3a
Autor:
Tumelo Akapelwa Muyenga, Samuel K. Dominion Bamitale, Dan Kibuule, Simbarashe Sithole, Stanley Mukanganyama, Carlen Rudolph, Luanne Venables, Anna C. Hattingh, Maryna van de Venter, Christian Chinyere Ezeala
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Diabetes affects 75% of people in low-income countries, where conventional drugs like metformin are available, but newer drugs like alpha-glucosidase inhibitors are not accessible to most Southern African patients. Aim To evaluate
Externí odkaz:
https://doaj.org/article/4bd815052ae5488597a5fd061eb9de69
Autor:
Atalanti Christou, Constantina Stavrou, Christodoulos Michael, George Botsaris, Vlasios Goulas
Publikováno v:
Microbiology Research, Vol 15, Iss 2, Pp 926-942 (2024)
Plants possess endless structural and chemical diversity, which is peerless with any synthetic library of small biomolecules, inspiring novel drug discovery. Plants are widely applied to encounter global health challenges such as antimicrobial resist
Externí odkaz:
https://doaj.org/article/9324357d5c2a48fcb3309ad60ef1b0cc
Publikováno v:
Journal of Pharmacy and Bioallied Sciences, Vol 16, Iss 6, Pp 1291-1294 (2024)
Diabetes mellitus is a persistent metabolic condition marked by elevated blood glucose levels due to compromised insulin secretion or functionality. The search for natural antidiabetic agents has gained attention due to their potential effectiveness
Externí odkaz:
https://doaj.org/article/14d348c31bfe4b65b47c8bc5f25a0a2c
Publikováno v:
Кубанский научный медицинский вестник, Vol 31, Iss 2, Pp 107-117 (2024)
Background. Infantile-onset form of Pompe disease (IOPD) comprises a progressive and fatal disease in the absence of pathogenetic treatment. Enzyme replacement therapy using biologically active recombinant human alglucosidase alfa is considered as a
Externí odkaz:
https://doaj.org/article/324f076bd1ad4835bfd9499f7e27858c
Publikováno v:
Phytomedicine Plus, Vol 4, Iss 3, Pp 100586- (2024)
Background: Piper longum L. is a tropical and subtropical medicinal plant that has been used as antidiabetic, diarrhea, stomachache, cough, asthma, and bronchitis since ancient times. The in vitro-grown callus from the leaf, however, has not been tes
Externí odkaz:
https://doaj.org/article/12a1999284124068a67f9e1f60c37442
Autor:
Valentina Martinez‐Montoya, Luz María Sánchez‐Sánchez, Roberto Sandoval‐Pacheco, Diana Mónica Anaya Castro, Carmen Araceli Arellano‐Valdez, Carmen Amor Ávila‐Rejón, Pedro Alejandro Aguilar‐Juárez, Martín Espino‐Pluma, Cruz Antonio González‐Santillanes, Rosa Isela Martínez‐Segovia, Dorian Olmos‐Morfin, Ofelia Padilla‐De laTorre, Ishar Solís‐Sánchez, Mónica Vázquez‐Del Mercado Espinosa, Camilo Ernesto Villarroel‐Cortés, Jesús Salvador Velarde‐Félix, Jaime López‐Valdez, Julio Olaiz‐Urbina, Edgar Ricárdez‐Marcial, Imelda Vergara‐Sánchez, Pablo Radillo‐Díaz, Ekaterina Kazakova, Beatriz De la Fuente‐Cortez, Luz delCarmen Marquez‐Quiróz, Benjamín Torres‐Octavo, Rubicel Diaz‐Martinez
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 12, Iss 7, Pp n/a-n/a (2024)
Abstract Background Pompe Disease (PD) is a metabolic myopathy caused by variants in the GAA gene, resulting in deficient enzymatic activity. We aimed to characterize the clinical features and related genetic variants in a series of Mexican patients.
Externí odkaz:
https://doaj.org/article/10c85aa27eff45718f043839c276dd00
Autor:
Thaniwan Cheun-Arom, Tharita Kitisripanya, Poomraphie Nuntawong, Boonchoo Sritularak, Taksina Chuanasa
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34502- (2024)
Eight compounds, including one anthraquinone, two bibenzyls, one phenanthrene, three dihydrophenanthrenes, and one flavonoid, were isolated from the roots of Dendrobium polyanthum Wall. ex Lindl. Among these, six compounds were investigated for inhib
Externí odkaz:
https://doaj.org/article/5166d97aa5fa4988ac965182158a952c