Zobrazeno 1 - 10
of 164
pro vyhledávání: '"alpha-7 nicotinic receptor"'
Publikováno v:
BioMedInformatics, Vol 2, Iss 4, Pp 553-564 (2022)
Omicron is the dominant strain of COVID-19 in the United States and worldwide. Although this variant is highly transmissible and may evade natural immunity, vaccines, and therapeutic antibodies, preclinical results in animal models and clinical data
Externí odkaz:
https://doaj.org/article/6224b96a11304c988037fbf9b4310f82
Autor:
Maral Aminpour, Marco Cannariato, Jordane Preto, M. Ehsan Safaeeardebili, Alexia Moracchiato, Domiziano Doria, Francesca Donato, Eric Adriano Zizzi, Marco Agostino Deriu, David E. Scheim, Alessandro D. Santin, Jack Adam Tuszynski
Publikováno v:
Computation, Vol 10, Iss 4, p 51 (2022)
Some clinical studies have indicated activity of ivermectin, a macrocyclic lactone, against COVID-19, but a biological mechanism initially proposed for this anti-viral effect is not applicable at physiological concentrations. This in silico investiga
Externí odkaz:
https://doaj.org/article/e6955eea9d134214b507a187472c4042
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Molecular dynamics simulations of the alpha-7 nicotinic receptor, both atomistic (ion permeation free energy calculation) and coarse-grained (lipid and drug binding).
Two amino residues were incorrectly assigned in the original PDB file. N35 sho
Two amino residues were incorrectly assigned in the original PDB file. N35 sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e780d5f32423b671cadb81670b64b4df
https://doi.org/10.1073/pnas.2208081119
https://doi.org/10.1073/pnas.2208081119
Akademický článek
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Akademický článek
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Publikováno v:
Schizophrenia Research. 222:283-290
It has been suggested the study of sub-groups within the syndrome of schizophrenia will assist in elucidating the complex pathophysiology of the syndrome. Hence, we have studied a number of cholinergic markers in the cortex from a sub-group of subjec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec78ffa83b28dc4f6dc92acd1f06472
https://doi.org/10.1016/j.schres.2020.05.034
https://doi.org/10.1016/j.schres.2020.05.034
Autor:
George M. Anderson, Russel J. Reiter
Publikováno v:
Melatonin Research. 3:322-345
As data emerges on the pathophysiological underpinnings of severe acute respiratory syndrome coronavirus (SARS-CoV)-2, it is clear that there are considerable variations in its susceptibility and severity/fatality, which give indications as to its pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcfe9be069e5c63b30b5cf744e2b510a
https://doi.org/10.32794/mr11250066
https://doi.org/10.32794/mr11250066
Molecular dynamics simulations of the alpha-7 nicotinic receptor, both atomistic (ion permeation free energy calculation) and coarse-grained (lipid and drug binding).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::501626a8c93a7be9102c02cb974bf22d
Autor:
Sami I. Alzarea, Shafiqur Rahman
Publikováno v:
Behavioural Brain Research. 366:19-28
Neuroinflammation is often associated with the development of major depressive disorder (MDD)-related symptoms. Previous studies have indicated that activation of glial cells, upregulation of proinflammatory cytokines and dysregulation of adrenergic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a48021b957f549cf69e276c9441c9d
https://doi.org/10.1016/j.bbr.2019.03.019
https://doi.org/10.1016/j.bbr.2019.03.019
Publikováno v:
Frontiers in Psychology, Vol 5 (2014)
Nicotine alters appetite and energy expenditure, leading to changes in body weight. While the exact mechanisms underlying these effects are not fully established, both central and peripheral involvement of the alpha-7 nicotinic acetylcholine receptor
Externí odkaz:
https://doaj.org/article/11a3df5388564d52883cb5be2b9b4272