Zobrazeno 1 - 10
of 4 044
pro vyhledávání: '"alpha therapy"'
Publikováno v:
iRADIOLOGY, Vol 2, Iss 4, Pp 396-411 (2024)
Abstract Targeted alpha (α) therapy (TAT) is an emerging therapeutic strategy for cancer treatment. To evaluate the safety and efficacy of targeted α‐therapy, the biodistribution and internal radiation dose of α‐emitting radionuclides should b
Externí odkaz:
https://doaj.org/article/8e574c0327a246fbb68ba7bcc4de0e16
Autor:
A. K. M. Rezaur Rahman, Mahathe Hasan Babu, Mustofa Khalid Ovi, Md. Mahiuddin Zilani, Israt Sultana Eithu, Amit Chakraborty
Publikováno v:
Journal of Medical Physics, Vol 49, Iss 2, Pp 137-147 (2024)
The utilization of actinium-225 (225Ac) radionuclides in targeted alpha therapy for cancer was initially outlined in 1993. Over the past two decades, substantial research has been conducted, encompassing the establishment of 225Ac production methods,
Externí odkaz:
https://doaj.org/article/fd3d3f7c0ce94a51827a26a032bbaa64
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-13 (2024)
Abstract Background A significant challenge in cancer therapy lies in eradicating hidden disseminated tumor cells. Within Nuclear Medicine, Targeted Alpha Therapy is a promising approach for cancer treatment tackling disseminated cancer. As tumor siz
Externí odkaz:
https://doaj.org/article/278aba369eb9421986b55d1c8c570cee
Autor:
Sadahiro Naka, Kazuhiro Ooe, Yoshifumi Shirakami, Kenta Kurimoto, Toshihiro Sakai, Kazuhiro Takahashi, Atsushi Toyoshima, Yang Wang, Hiromitsu Haba, Hiroki Kato, Noriyuki Tomiyama, Tadashi Watabe
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-15 (2024)
Abstract Background The alpha emitter astatine-211 (211At) is garnering attention as a novel targeted alpha therapy for patients with refractory thyroid cancer resistant to conventional therapy using beta emitter radioiodine (131I). Herein, we aimed
Externí odkaz:
https://doaj.org/article/bd01fd012682447aa829e33c3d3df674
Autor:
Bianca Schacherl, Kiara Maurer, Martin Schäfer, Yvonne Remde, Frank Geyer, Annika Fried, Steffen Alexander Happel, Martina Benešová-Schäfer
Publikováno v:
Frontiers in Nuclear Engineering, Vol 3 (2024)
Targeted alpha therapy (TαT) represents an emerging and cutting-edge treatment option for patients dealing with highly challenging metastatic cancer diseases. Critically, the limited supply of alpha-particle-emitting radionuclides, so-called alpha i
Externí odkaz:
https://doaj.org/article/9fcb4d9841b243b7b135adad652ad5ab
Autor:
Eline L. Hooijman, Valery Radchenko, Sui Wai Ling, Mark Konijnenberg, Tessa Brabander, Stijn L. W. Koolen, Erik de Blois
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-30 (2024)
Abstract Background In the past years, there has been a notable increase in interest regarding targeted alpha therapy using Ac-225, driven by the observed promising clinical anti-tumor effects. As the production and technology has advanced, the avail
Externí odkaz:
https://doaj.org/article/ea3b5e881d0946de8f0c7f54613517f6
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 8, Iss 1, Pp 1-27 (2023)
Abstract Background The alpha-emitter radium-223 (223Ra) is presently used in nuclear medicine for the palliative treatment of bone metastases from castration-resistant prostate cancer. This application arises from its advantageous decay properties a
Externí odkaz:
https://doaj.org/article/b8a92ffbe0d0467f8c801e2fa88dbcc7
Autor:
Ruth Christine Winter, Mariam Amghar, Anja S. Wacker, Gábor Bakos, Harun Taş, Mareike Roscher, James M. Kelly, Martina Benešová-Schäfer
Publikováno v:
Pharmaceuticals, Vol 17, Iss 8, p 1031 (2024)
Cancer is one of the most complex and challenging human diseases, with rising incidences and cancer-related deaths despite improved diagnosis and personalized treatment options. Targeted alpha therapy (TαT) offers an exciting strategy emerging for c
Externí odkaz:
https://doaj.org/article/cb8cc3ceddcb4530a7476bd0717f108c
Publikováno v:
iRADIOLOGY, Vol 1, Iss 3, Pp 245-261 (2023)
Abstract Alpha emitters are radionuclides with good pharmacological characteristics for the treatment of cancer because they decay by emitting high linear energy transfer particles. Recent advancements in isotope production and purification and the g
Externí odkaz:
https://doaj.org/article/0072393980a2485bb73bffb9ce80ef65
Autor:
Anders Josefsson, Angel G. Cortez, Harikrishnan Rajkumar, Joseph D. Latoche, Ambika P. Jaswal, Kathryn E. Day, Mohammadreza Zarisfi, Lora H. Rigatti, Ziyu Huang, Jessie R. Nedrow
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 8, Iss 1, Pp 1-19 (2023)
Abstract Background The liver is a common site for metastatic disease for a variety of cancers, including colorectal cancer. Both primary and secondary liver tumors are supplied through the hepatic artery while the healthy liver is supplied by the po
Externí odkaz:
https://doaj.org/article/5bdb66bc79a74d4192cbef491bb17580