Zobrazeno 1 - 10
of 79
pro vyhledávání: '"alpha globin genes"'
Autor:
Sergey V. Ulianov, Aleksandra A. Galitsyna, Ilya M. Flyamer, Arkadiy K. Golov, Ekaterina E. Khrameeva, Maxim V. Imakaev, Nezar A. Abdennur, Mikhail S. Gelfand, Alexey A. Gavrilov, Sergey V. Razin
Publikováno v:
Epigenetics & Chromatin, Vol 10, Iss 1, Pp 1-19 (2017)
Abstract Background In homeotherms, the alpha-globin gene clusters are located within permanently open genome regions enriched in housekeeping genes. Terminal erythroid differentiation results in dramatic upregulation of alpha-globin genes making the
Externí odkaz:
https://doaj.org/article/5faf277341c547219a288c47cf1b9b1f
Autor:
Elza Miyuki Kimura, Denise Madureira Oliveira, Susan Elisabeth Jorge, Daniela Maria Ribeiro, Tânia Regina Zaccariotto, Magnun Nueldo Nunes Santos, Vanessa Almeida, Dulcinéia Martins Albuquerque, Fernando Ferreira Costa, Maria de Fátima Sonati
Publikováno v:
Revista Brasileira de Hematologia e Hemoterapia, Vol 37, Iss 2, Pp 103-108 (2015)
Background: Brazil has a multiethnic population with a high diversity of hemoglobinopathies. While screenings for beta-globin mutations are far more common, alterations affecting alpha-globin genes are usually more silent and less well known. The aim
Externí odkaz:
https://doaj.org/article/26ced1cda486421d92d57652b39af210
Publikováno v:
Diversity, Vol 2, Iss 4, Pp 679-700 (2010)
This report is a review of some of the results obtained over the course of 20 years spent investigating hemoglobin phenotypes and the related functional effects on hematological patterns in ruminant breeds. Tests included qualitative and quantitative
Externí odkaz:
https://doaj.org/article/fd830dc5e1cb45bc9e401f25f46fdea4
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 42, Iss 9, Pp 783-786 (2009)
The α-MRE is the major regulatory element responsible for the expression of human α-like globin genes. It is genetically polymorphic, and six different haplotypes, named A to F, have been identified in some population groups from Europe, Africa and
Externí odkaz:
https://doaj.org/article/3773b3d839e54b27b0cd625edfbe3403
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 36, Iss 11, Pp 1471-1474 (2003)
Point mutations and small insertions or deletions in the human alpha-globin genes may produce alpha-chain structural variants and alpha-thalassemia. Mutations can be detected either by direct DNA sequencing or by screening methods, which select the m
Externí odkaz:
https://doaj.org/article/bd66567593d14738994e6ff58cdbff8a
Autor:
M.R.S.C. Wenning, E.M. Kimura, F.F. Costa, S.T.O. Saad, S. Gervásio, S.B. de Jorge, E. Borges, N.M. Silva, M.F. Sonati
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 33, Iss 9, Pp 1041-1045 (2000)
Seven unrelated patients with hemoglobin (Hb) H disease and 27 individuals with alpha-chain structural alterations were studied to identify the alpha-globin gene mutations present in the population of Southeast Brazil. The -alpha3.7, --MED and -(alph
Externí odkaz:
https://doaj.org/article/04289be81d964a58b4639b9c630c35c0
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 36, Iss 6, Pp 699-701 (2003)
We report a case in which the interaction of heterozygosis for both the ß0-IVS-II-1 (G->A) mutation and the aaaanti-3.7 allele was the probable cause for the clinical occurrence of thalassemia intermedia. The propositus, a 6-year-old Caucasian Brazi
Externí odkaz:
https://doaj.org/article/77c4bc104f894b429fe6e142284a61ed
Autor:
Nezar Abdennur, Mikhail S. Gelfand, Arkadiy K. Golov, Aleksandra A. Galitsyna, Alexey A. Gavrilov, Maxim Imakaev, Sergey V. Ulianov, Ekaterina Khrameeva, Ilya M. Flyamer, Sergey V. Razin
Publikováno v:
Epigenetics & Chromatin, Vol 10, Iss 1, Pp 1-19 (2017)
Epigenetics & Chromatin
Epigenetics & Chromatin
Background In homeotherms, the alpha-globin gene clusters are located within permanently open genome regions enriched in housekeeping genes. Terminal erythroid differentiation results in dramatic upregulation of alpha-globin genes making their expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7304028c4a990d96d2b2785f0924f656
http://link.springer.com/article/10.1186/s13072-017-0142-4
http://link.springer.com/article/10.1186/s13072-017-0142-4
Akademický článek
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Publikováno v:
Diversity, Vol 2, Iss 4, Pp 679-700 (2010)
This report is a review of some of the results obtained over the course of 20 years spent investigating hemoglobin phenotypes and the related functional effects on hematological patterns in ruminant breeds. Tests included qualitative and quantitative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2243ae4e3a8d98132748956ccd5ffe
http://www.mdpi.com/1424-2818/2/4/679/
http://www.mdpi.com/1424-2818/2/4/679/