Zobrazeno 1 - 10
of 151
pro vyhledávání: '"almonertinib"'
Publikováno v:
Pharmaceutical Biology, Vol 62, Iss 1, Pp 874-881 (2024)
Context Almonertinib is primarily metabolized by CYP3A4, so it could interact with a variety of drugs metabolized by CYP3A4, leading to the changes of systemic exposure.Objective For the purpose of this experiment, an ultra-performance liquid chromat
Externí odkaz:
https://doaj.org/article/1a2e8cd8b4c44c0384c3efa5674d718c
Autor:
Cheng Sun, Zhike Liang, Zhiyun Yan, Yawen Feng, Wanna Tang, Shuquan Wei, Weinong Zhong, Ziwen Zhao, Yujun Li
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Acute respiratory distress syndrome (ARDS) is a life-threatening condition frequently encountered in critically ill patients, including those with advanced non-small cell lung cancer (NSCLC). Almonertinib, a third-generation epide
Externí odkaz:
https://doaj.org/article/f2af7252c0664acb80e3551bed92d588
Publikováno v:
Thoracic Cancer, Vol 15, Iss 23, Pp 1757-1763 (2024)
Abstract Background Epidermal growth factor receptor (EGFR) mutations are key drivers in a significant portion of non‐small‐cell lung cancer (NSCLC) patients. While third‐generation EGFR‐tyrosine kinase inhibitors (TKIs) such as osimertinib h
Externí odkaz:
https://doaj.org/article/a723a07ac722459eaa7b4f28f3ca4fe7
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroudHuman epithelial growth factor receptor 2 (HER2) amplification is an important mechanism of acquired resistance to anti-epidermal growth factor receptor (EGFR) therapy in non-small cell lung cancer (NSCLC) patients. For patients with both EG
Externí odkaz:
https://doaj.org/article/bdc2fb16a5fd4223b16d23794361fef7
Akademický článek
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Autor:
Teng Chen, Pei Zhang, Xiao-Fan Cong, Yuan-Yuan Wang, Shuo Li, Hao Wang, Su-Rong Zhao, Xiao-Jin Sun
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionAlmonertinib is an important third-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) exhibiting high selectivity to EGFR-sensitizing and T790M-resistant mutations. Almonertinib resistance is a major obstacle
Externí odkaz:
https://doaj.org/article/77df71a69b724dff9768e04042d547b8
Autor:
Chen Shi, Cong Wang, Zhiwen Fu, Jinmei Liu, Yuanfeng Zhou, Bao Cheng, Cong Zhang, Shijun Li, Yu Zhang
Publikováno v:
Pharmacological Research, Vol 201, Iss , Pp 107088- (2024)
Almonertinib, a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, is highly selective for EGFR-activating mutations as well as the EGFR T790M mutation in patients with advanced non-small cell lung cancer (NSCLC). How
Externí odkaz:
https://doaj.org/article/a3e54a3211f14d718d8a83781cc0e5b8
Publikováno v:
The Clinical Respiratory Journal, Vol 17, Iss 7, Pp 647-653 (2023)
Abstract Introduction The metastases of lung cancer to bilateral choroids symmetrically and simultaneously are very rare. Almost all patients with choroid metastasis can be treated with external beam radiotherapy in order to increase quality of life
Externí odkaz:
https://doaj.org/article/c7c2096073e743a1a9f81184c2a8a5cd
Autor:
Tianli Wang, Qin Zheng, Cong Deng, Xiang Li, Jia Huang, Jun Fan, Bo Huang, Jiwei Zhang, Xiaona Chang, Xiu Nie
Publikováno v:
Respiratory Medicine Case Reports, Vol 50, Iss , Pp 102051- (2024)
The advancement of molecular pathology techniques has led to the discovery of rare EGFR mutations for targeted therapy in lung cancer. Additionally, a substantial body of evidence indicates a connection between the development of lung cancer and gene
Externí odkaz:
https://doaj.org/article/9601d942fd714812bd125fe6bc391813
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background With the use of targeted drugs in lung cancer patients, targeted drug-induced interstitial lung disease (ILD) has attracted more and more attention. The incidence, time, and severity of different targeted drug-induced ILD vary. Al
Externí odkaz:
https://doaj.org/article/62971449985b4299b606bf45fd71c41e