Zobrazeno 1 - 10
of 73 626
pro vyhledávání: '"allosteric"'
Autor:
Li N; Key Laboratory of Protection, Development and Utilization of Medicinal Resources in Liupanshan Area, Ministry of Education, Peptide & Protein Drug Research Center, School of Pharmacy, Ningxia Medical University, Yinchuan 750004, China; Medicinal Chemistry and Bioinformatics Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China., Zheng G; Department of VIP Clinic, Changhai Hospital, Affiliated to Naval Medical University, Shanghai 200433, China., Fu L; Department of Nephrology, People's Hospital of Pudong New Area, Shanghai University of Medicine & Health Sciences, Shanghai 201299, China., Liu N; Key Laboratory of Protection, Development and Utilization of Medicinal Resources in Liupanshan Area, Ministry of Education, Peptide & Protein Drug Research Center, School of Pharmacy, Ningxia Medical University, Yinchuan 750004, China., Chen T; Department of Cardiology, Changzheng Hospital, Affiliated to Naval Medical University, Shanghai 200003, China. Electronic address: pipidan@126.com., Lu S; Key Laboratory of Protection, Development and Utilization of Medicinal Resources in Liupanshan Area, Ministry of Education, Peptide & Protein Drug Research Center, School of Pharmacy, Ningxia Medical University, Yinchuan 750004, China; Medicinal Chemistry and Bioinformatics Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. Electronic address: lushaoyong@sjtu.edu.cn.
Publikováno v:
Drug discovery today [Drug Discov Today] 2024 Oct; Vol. 29 (10), pp. 104141. Date of Electronic Publication: 2024 Aug 19.
Autor:
Wang M; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou 450001, Henan, China., Liu H; Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450001, Henan, China., Fu X; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou 450001, Henan, China., Yang L; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou 450001, Henan, China. Electronic address: yanglin-89@zzu.edu.cn.
Publikováno v:
International journal of biological macromolecules [Int J Biol Macromol] 2024 Nov; Vol. 281 (Pt 4), pp. 136453. Date of Electronic Publication: 2024 Oct 09.
Autor:
Liu Y; Interdisciplinary Research Center for Biology and Chemistry, Liaoning Normal University, Dalian, 116029, China; Laboratory of Molecular Modeling and Design, State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China., Li Y; Interdisciplinary Research Center for Biology and Chemistry, Liaoning Normal University, Dalian, 116029, China; Laboratory of Molecular Modeling and Design, State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China., Li G; Interdisciplinary Research Center for Biology and Chemistry, Liaoning Normal University, Dalian, 116029, China; Laboratory of Molecular Modeling and Design, State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China., Wang A; Interdisciplinary Research Center for Biology and Chemistry, Liaoning Normal University, Dalian, 116029, China; Laboratory of Molecular Modeling and Design, State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China. Electronic address: wangah@lnnu.edu.cn., Chu H; Interdisciplinary Research Center for Biology and Chemistry, Liaoning Normal University, Dalian, 116029, China; Laboratory of Molecular Modeling and Design, State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China. Electronic address: chuhy2009@dicp.ac.cn.
Publikováno v:
Archives of biochemistry and biophysics [Arch Biochem Biophys] 2024 Oct; Vol. 760, pp. 110137. Date of Electronic Publication: 2024 Aug 30.
Autor:
Nussinov R; Computational Structural Biology Section, Frederick National Laboratory for Cancer Research in the Cancer Innovation Laboratory, National Cancer Institute, Frederick, MD, USA.; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel., Jang H; Computational Structural Biology Section, Frederick National Laboratory for Cancer Research in the Cancer Innovation Laboratory, National Cancer Institute, Frederick, MD, USA.
Publikováno v:
Expert opinion on drug discovery [Expert Opin Drug Discov] 2024 Sep; Vol. 19 (9), pp. 1071-1085. Date of Electronic Publication: 2024 Jul 28.
Autor:
Peter S; Computational Chemistry, Nxera Pharma U.K., Steinmetz Building, Granta Park, Cambridge CB21 6DG, United Kingdom.; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Piazza Rinascimento 6, Urbino 61029, Italy., Siragusa L; Kinetic Business Centre, Molecular Discovery Ltd., Theobald Street, Elstree, Borehamwood, Hertfordshire WD6 4PJ, United Kingdom.; Molecular Horizon srl, via Montelino 30, Bettona, PG 06084, Italy., Thomas M; Computational Chemistry, Nxera Pharma U.K., Steinmetz Building, Granta Park, Cambridge CB21 6DG, United Kingdom.; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., Palomba T; Kinetic Business Centre, Molecular Discovery Ltd., Theobald Street, Elstree, Borehamwood, Hertfordshire WD6 4PJ, United Kingdom., Cross S; Kinetic Business Centre, Molecular Discovery Ltd., Theobald Street, Elstree, Borehamwood, Hertfordshire WD6 4PJ, United Kingdom., O'Boyle NM; Computational Chemistry, Nxera Pharma U.K., Steinmetz Building, Granta Park, Cambridge CB21 6DG, United Kingdom., Bajusz D; Medicinal Chemistry Research Group and Drug Innovation Centre, HUN-REN Research Centre for Natural Sciences, Magyar tudósok krt. 2, Budapest 1117, Hungary., Ferenczy GG; Medicinal Chemistry Research Group and Drug Innovation Centre, HUN-REN Research Centre for Natural Sciences, Magyar tudósok krt. 2, Budapest 1117, Hungary., Keserű GM; Medicinal Chemistry Research Group and Drug Innovation Centre, HUN-REN Research Centre for Natural Sciences, Magyar tudósok krt. 2, Budapest 1117, Hungary., Bottegoni G; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Piazza Rinascimento 6, Urbino 61029, Italy.; Institute of Clinical Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom., Bender B; Computational Chemistry, Nxera Pharma U.K., Steinmetz Building, Granta Park, Cambridge CB21 6DG, United Kingdom., Chen I; Computational Chemistry, Nxera Pharma U.K., Steinmetz Building, Granta Park, Cambridge CB21 6DG, United Kingdom., De Graaf C; Computational Chemistry, Nxera Pharma U.K., Steinmetz Building, Granta Park, Cambridge CB21 6DG, United Kingdom.
Publikováno v:
Journal of chemical information and modeling [J Chem Inf Model] 2024 Nov 11; Vol. 64 (21), pp. 8176-8192. Date of Electronic Publication: 2024 Oct 23.
Autor:
Bartocci A; Institut de Chimie de Strasbourg, UMR7177, CNRS, Université de Strasbourg, Strasbourg Cedex, 67083, France.; Department of Physics, University of Trento, Via Sommarive 14, I-38123, Trento, Italy.; INFN-TIFPA, Trento Institute for Fundamental Physics and Applications, Via Sommarive 14, I-38123, Trento, Italy., Grazzi A; Institut de Chimie de Strasbourg, UMR7177, CNRS, Université de Strasbourg, Strasbourg Cedex, 67083, France.; Department of Chemistry, University of Milan, Via C. Golgi 19, Milan, 20133, Italy., Awad N; Institut Pasteur, Université de Paris, CNRS UMR3571, Channel-Receptors Unit, Paris, France., Corringer PJ; Institut Pasteur, Université de Paris, CNRS UMR3571, Channel-Receptors Unit, Paris, France., Souza PCT; Laboratoire de Biologie et Modélisation de la Cellule, CNRS, UMR 5239, Inserm, U1293, Université Claude Bernard Lyon 1, Ecole Normale Supérieure de Lyon, 46 Allée d'Italie, 69364, Lyon, France.; Centre Blaise Pascal de Simulation et de Modélisation Numérique, Ecole Normale Supérieure de Lyon, 46 Allée d'Italie, 69364, Lyon, France., Cecchini M; Institut de Chimie de Strasbourg, UMR7177, CNRS, Université de Strasbourg, Strasbourg Cedex, 67083, France. mcecchini@unistra.fr.
Publikováno v:
Nature communications [Nat Commun] 2024 Oct 19; Vol. 15 (1), pp. 9040. Date of Electronic Publication: 2024 Oct 19.
Autor:
Tee WV; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, Singapore 138671, Singapore., Lim SJM; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, Singapore 138671, Singapore., Berezovsky IN; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, Singapore 138671, Singapore.; Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive, Singapore 117579, Singapore.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2024 Oct 10; Vol. 67 (19), pp. 17191-17206. Date of Electronic Publication: 2024 Sep 26.
Autor:
Chen X; College of Chemistry, Sichuan University, Chengdu, China., Wang K; Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China., Chen J; College of Chemistry, Sichuan University, Chengdu, China., Wu C; Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China., Mao J; College of Chemistry, Sichuan University, Chengdu, China., Song Y; College of Chemistry, Sichuan University, Chengdu, China., Liu Y; College of Computer Science, Sichuan University, Chengdu, China., Shao Z; Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China. zhenhuashao@scu.edu.cn.; Frontiers Medical Center, Tianfu Jincheng Laboratory, Chengdu, China. zhenhuashao@scu.edu.cn., Pu X; College of Chemistry, Sichuan University, Chengdu, China. xmpuscu@scu.edu.cn.
Publikováno v:
Nature communications [Nat Commun] 2024 Sep 16; Vol. 15 (1), pp. 8130. Date of Electronic Publication: 2024 Sep 16.
Autor:
Lin YY; School of Basic Medicine and Clinical Pharmacy, and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China., Lu Y; School of Basic Medicine and Clinical Pharmacy, and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China., Li CY; School of Basic Medicine and Clinical Pharmacy, and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China., Ma XF; School of Basic Medicine and Clinical Pharmacy, and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China., Shao MQ; School of Basic Medicine and Clinical Pharmacy, and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China., Gao YH; School of Basic Medicine and Clinical Pharmacy, and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China., Zhang YQ; School of Basic Medicine and Clinical Pharmacy, and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China., Jiang HN; Departments of Chemical Biology and Pharmacology, College of Basic Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Liu Y; Departments of Chemical Biology and Pharmacology, College of Basic Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Yang Y; Departments of Chemical Biology and Pharmacology, College of Basic Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Huang LD; Departments of Chemical Biology and Pharmacology, College of Basic Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Cao P; Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China., Wang HS; State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, Collaborative Innovation Center for Guangxi Ethnic Medicine, School of Chemistry and Pharmaceutical Sciences of Guangxi Normal University, Guilin, China. whengshan@163.com., Wang J; School of Basic Medicine and Clinical Pharmacy, and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China. wangjin@cpu.edu.cn.; School of Science, China Pharmaceutical University, Nanjing, China. wangjin@cpu.edu.cn., Yu Y; School of Basic Medicine and Clinical Pharmacy, and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China. yuye@cpu.edu.cn.; Departments of Chemical Biology and Pharmacology, College of Basic Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China. yuye@cpu.edu.cn.; Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China. yuye@cpu.edu.cn.
Publikováno v:
Nature communications [Nat Commun] 2024 Sep 03; Vol. 15 (1), pp. 7652. Date of Electronic Publication: 2024 Sep 03.
Autor:
Raza SHA; Guangdong Provincial Key Laboratory of Food Quality and Safety/Nation-Local Joint Engineering Research Center for Machining and Safety of Livestock and Poultry Products, South China Agricultural University, Guangzhou, 510642, China.; Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region, Shaoguan University, Shaoguan, 512005, China.; College of Animal Science and Technology, Northwest A&F University, Yangling, 712100, Shaanxi, China., Zhong R; Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region, Shaoguan University, Shaoguan, 512005, China., Yu X; Guangdong Provincial Key Laboratory of Food Quality and Safety/Nation-Local Joint Engineering Research Center for Machining and Safety of Livestock and Poultry Products, South China Agricultural University, Guangzhou, 510642, China., Zhao G; Guangdong Provincial Key Laboratory of Food Quality and Safety/Nation-Local Joint Engineering Research Center for Machining and Safety of Livestock and Poultry Products, South China Agricultural University, Guangzhou, 510642, China., Wei X; Guangdong Provincial Key Laboratory of Food Quality and Safety/Nation-Local Joint Engineering Research Center for Machining and Safety of Livestock and Poultry Products, South China Agricultural University, Guangzhou, 510642, China., Lei H; Guangdong Provincial Key Laboratory of Food Quality and Safety/Nation-Local Joint Engineering Research Center for Machining and Safety of Livestock and Poultry Products, South China Agricultural University, Guangzhou, 510642, China. hongtao@scau.edu.cn.; Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou, 510642, China. hongtao@scau.edu.cn.; Licheng Detection and Certification Group Co., Ltd., Zhongshan, 528403, Guangdong, China. hongtao@scau.edu.cn.
Publikováno v:
Molecular biotechnology [Mol Biotechnol] 2024 Dec; Vol. 66 (12), pp. 3385-3397. Date of Electronic Publication: 2023 Nov 13.