ADCC-Inducing Antibody Trastuzumab and Selection of KIR-HLA Ligand Mismatched Donors Enhance the NK Cell Anti-Breast Cancer Response

Autor: Femke A I Ehlers, Nicky A. Beelen, Lotte Wieten, Tom M J Evers, Michel van Gelder, Gerard M. J. Bos, Loes F. S. Kooreman, Marjolein L. Smidt

Publikováno v: Cancers
Volume 13
Issue 13
Cancers, 13(13):3232. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers, Vol 13, Iss 3232, p 3232 (2021)

Simple Summary Natural killer (NK) cells are potent killers of tumor cells. Many tumors, including breast cancers, develop mechanisms to suppress anti-tumor immune responses, requiring the development of strategies to overcome suppression. Here, we t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcc1a5315adf4a79a1b13c86449fbe52
https://doi.org/10.3390/cancers13133232