Zobrazeno 1 - 10
of 5 695
pro vyhledávání: '"all‐trans retinoic acid"'
Publikováno v:
Case Reports in Oncology, Vol 17, Iss 1, Pp 1103-1108 (2024)
Introduction: All-trans retinoic acid (ATRA) in combination with arsenic trioxide (ATO) is standard therapy for low-to-intermediate risk acute promyelocytic leukemia (APL). Isotretinoin, an agent used for acne vulgaris, is similar in its chemical str
Externí odkaz:
https://doaj.org/article/e414ca4149b54e89aad6513d423063cf
Publikováno v:
Shanghai Jiaotong Daxue xuebao. Yixue ban, Vol 44, Iss 9, Pp 1083-1093 (2024)
Objective·To explore the effect of all-trans retinoic acid (ATRA) of different concentrations on osteogenic differentiation of jaw bone mesenchymal stem cells (jBMSCs) in rats.Methods·jBMSCs from 4-week-old Sprague-Dawley (SD) rats were isolated an
Externí odkaz:
https://doaj.org/article/6bebc76c0bb84550ae171d564c6d5090
Publikováno v:
Journal of Pediatric Research, Vol 11, Iss 3, Pp 185-188 (2024)
All-trans retinoic acid (ATRA), a derivative of vitamin A, has dramatically altered the treatment landscape for acute promyelocytic leukemia (APL). APL is characterized by the abnormal maturation of myeloid cells, which become arrested at the promyel
Externí odkaz:
https://doaj.org/article/906355b70e864180a4ea52df31bfa528
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background Cancer stem-like cells (CSCs) play an important role in initiation and progression of aggressive cancers, including esophageal cancer. Natural killer (NK) cells are key effector lymphocytes of innate immunity that directly attack
Externí odkaz:
https://doaj.org/article/f6d15bc0d3e941caab1271ef07d0a32e
Publikováno v:
Blood and Lymphatic Cancer: Targets and Therapy, Vol Volume 14, Pp 63-69 (2024)
Dan Liu, Juan Tong, Erling Chen, Li Wang, Lei Xue, Xuhan Zhang, Na Zhao, Xing Hu, Changcheng Zheng Department of Hematology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China,
Externí odkaz:
https://doaj.org/article/5b73b1ada736413ca02dfc5384cca944
Publikováno v:
Cancer Reports, Vol 7, Iss 11, Pp n/a-n/a (2024)
ABSTRACT Background Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia defined by a fusion gene transcript called PML::RARA. Pseudotumor cerebri (PTC) is characterized by elevated intracranial pressure (ICP) and presents with p
Externí odkaz:
https://doaj.org/article/82f6fc2f413b4b3881b780b23c10c533
Autor:
Pavel Hrabak, Miroslava Zelenkova, Tomas Krechler, Jan Soupal, Michal Vocka, Tomas Hanus, Lubos Petruzelka, Stepan Svacina, Ales Zak, Tomas Zima, Marta Kalousova
Publikováno v:
Biomedical Papers, Vol 168, Iss 2, Pp 132-138 (2024)
Aims. Retinoids participate in multiple key processes in the human body e.g., vision, cell differentiation and embryonic development. There is growing evidence of the relationship between retinol, its active metabolite- all-trans retinoic acid (ATRA)
Externí odkaz:
https://doaj.org/article/2668b0ec7d544fca9c18f5a5b5c0e61e
Autor:
Giovanna Farruggia, Lorenzo Anconelli, Lucrezia Galassi, Manuela Voltattorni, Martina Rossi, Pietro Lodeserto, Paolo Blasi, Isabella Orienti
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Acute promyelocytic leukemia (APL) is characterized by rearrangements of the retinoic acid receptor, RARα, which makes all-trans retinoic acid (ATRA) highly effective in the treatment of this disease, inducing promyelocytes differentiation.
Externí odkaz:
https://doaj.org/article/4a10973b0c8341c9a383e4eb39c2a3e7
Autor:
Samah Semary, Mahmoud Hammad, Dina Yassin, Nahla El Sharkawy, Sonya Soliman, Sherine Salem, Emad Ezzat, Ahmed Mosa, Sonia Ahmed
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background Pediatric acute promyelocytic leukemia (APL) accounts for 5 to 15% of all myelocytic leukemia. A retrospective analysis of pediatric patients diagnosed and treated with APL was conducted at CCHE from July 2012 to the end of Decemb
Externí odkaz:
https://doaj.org/article/8469b0b91b3449a5b8466d814f7848f9
Publikováno v:
Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-7 (2024)
Abstract Background All-trans retinoic acid (ATRA) is an indispensable part of the treatment of acute promyelocytic leukemia (APL). Although, mild cutaneous toxicities like mucocutaneous xerosis, rash, and pruritus are well reported, ATRA associated
Externí odkaz:
https://doaj.org/article/ec06ded2da7f484180717888aafa0807