Zobrazeno 1 - 10
of 232
pro vyhledávání: '"aldh1a3"'
Autor:
Alamelu G. Bharadwaj, Meghan E. McLean, Margaret L. Dahn, Hannah F. Cahill, Marie‐Claire D. Wasson, Raj Pranap Arun, Olivia L. Walker, Brianne M. Cruickshank, Wasundara Fernando, Jaganathan Venkatesh, Penelope J. Barnes, Gillian Bethune, Gregory Knapp, Lucy K. Helyer, Carman A. Giacomantonio, David M. Waisman, Paola Marcato
Publikováno v:
Molecular Oncology, Vol 18, Iss 1, Pp 91-112 (2024)
Aldehyde dehydrogenase 1A3 (ALDH1A3) is a cancer stem cell marker that promotes metastasis. Triple‐negative breast cancer (TNBC) progression has been linked to ALDH1A3‐induced gene expression changes. To investigate the mechanism of ALDH1A3‐med
Externí odkaz:
https://doaj.org/article/3963ad169532432cb23f181c5b3a6969
Autor:
Lorenzo Magrassi, Giulia Pinton, Sabino Luzzi, Sergio Comincini, Andrea Scravaglieri, Valentina Gigliotti, Bianca Laura Bernardoni, Ilaria D’Agostino, Francesca Juretich, Concettina La Motta, Silvia Garavaglia
Publikováno v:
Cancers, Vol 16, Iss 13, p 2397 (2024)
Aldehyde dehydrogenases of the subfamily 1A (ALDH1A) are enzymes necessary for the oxidation of all-trans or 9-cis retinal to retinoic acid (RA). Retinoic acid and its derivatives are important for normal development and maintenance of epithelia, rep
Externí odkaz:
https://doaj.org/article/90df43485fdf4270ba529eb34e209335
Autor:
Yifan Lv, Zusen Yuan, Dongmao Chen, Zhibin Chen, Xiaowei Zhu, Xiaoling Ying, Yapeng Huang, Weidong Ji, Defeng Qi
Publikováno v:
Non-coding RNA Research, Vol 9, Iss 4, Pp 1235-1248 (2024)
Background: Circular RNAs (circRNAs) have been identified as playing an integral role in the development of bladder cancer (BC). However, the mechanism by which circRNAs operate in the chemical carcinogenesis of BC remains unclear. Methods: To explor
Externí odkaz:
https://doaj.org/article/aaf63a446b3146f6a4f2999c7ec451d9
Autor:
Haoli Yin, Haixiang Qin, Lei Yang, Mengxia Chen, Yang Yang, Wenlong Zhang, Jiange Hao, Qun Lu, Jingyan Shi, Junlong Zhuang, Xuefeng Qiu, Hongqian Guo
Publikováno v:
Biomarker Research, Vol 10, Iss 1, Pp 1-20 (2022)
Abstract Background Docetaxel (DTX) is the most widely prescribed first-line chemotherapy for advanced prostate cancer (PCa). Unfortunately, DTX resistance invariably emerges, leading to worse prognosis of PCa. Growing evidence has shown that circRNA
Externí odkaz:
https://doaj.org/article/fe1163d863574fb69ab8ffa5eca94787
Autor:
Zhen Chen, Rainer Will, Su Na Kim, Maike Anna Busch, Nicole Dünker, Philipp Dammann, Ulrich Sure, Yuan Zhu
Publikováno v:
Cancers, Vol 15, Iss 17, p 4422 (2023)
Hyper-angiogenesis is a typical feature of glioblastoma (GBM), the most aggressive brain tumor. We have reported the expression of aldehyde dehydrogenase 1A3 (ALDH1A3) in proliferating vasculature in GBM patients. We hypothesized that ALDH1A3 may act
Externí odkaz:
https://doaj.org/article/50b84c72ad0147cab01e7c5359e889b9
Akademický článek
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Akademický článek
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Publikováno v:
Türk Biyokimya Dergisi, Vol 47, Iss 4, Pp 445-455 (2022)
Aim of the study was to reveal new biomarker genes to target breast cancer stem-like cells (BCSC-like) and then sensitize BCSC-like cells to chemotherapy by silencing MDR1 gene found to be the most suitable target.
Externí odkaz:
https://doaj.org/article/cefa8d9599c541e1883803428329a942
Akademický článek
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Autor:
Sara Boumya, Silvia Fallarini, Sonia Siragusa, Giovanni Petrarolo, Silvio Aprile, Valentina Audrito, Concettina La Motta, Silvia Garavaglia, Laura Moro, Giulia Pinton
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6689 (2023)
Aldehyde dehydrogenase 1A3 (ALDH1A3), one of the three members of the aldehyde dehydrogenase 1A subfamily, has been associated with increased progression and drug resistance in various types of solid tumours. Recently, it has been reported that high
Externí odkaz:
https://doaj.org/article/b9a052f5b30a406eb65bca0552f63ab9