Novel acetamide derivatives of 2-aminobenzimidazole prevent inflammatory arthritis in rats via suppression of pro-inflammatory mediators

Autor: Aymun Madni Zubair, Muhammad Nasir Hayat Malik, Waqas Younis, Muhammad Atif Hayat Malik, Shah Jahan, Ishtiaq Ahmed, Alamgeer Yuchi, Muhammad Naveed Mushtaq, Romeeza Tahir, Muhammad Bilal Sarwar, Muhammad Roman, Ayaz Ali Khan, Muhammad Nouman Tahir, Muhammad Tariq Khan, Hafiz Amir Ali Kharl, Gagun Kamran, Abdullah Abdo Albegali, Ali Imran

Publikováno v: Inflammopharmacology. 30:1005-1019

Benzimidazole ring system is an important pharmacophore with diverse pharmacological activities. In this study, we explored the anti-arthritic effects of newly synthesized acetamide derivatives of 2-aminobenzimidazole (N1 and N2) in rats. FTIR and NM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d222eb4bc57a43a0757ea516d832e98
https://doi.org/10.1007/s10787-022-00969-1

Evaluation of Analgesic and Anti-inflammatory Effects of 5-amino-3-phenyl-1,3,5-thiadiazine-2-thione in Mice

Autor: alamgeer yuchi, Zahid Rasul Niazi, Kiffayat Ullah Shah, Hamid Rasul Niazi, Rasool Khan, Muhammad Javid Khan, Hafiz Muhammad Irfan, Gowhar Ali, Kamran Ahmad Khan, Junaid Athar, Humayun Khattak, Taseer Ahmad

Purpose: The purpose of the study is to evaluate the analgesic and anti-inflammatory activity of new synthetic compound: 5-amino-3-phenyl-1,3,5-thiadiazine-2-thione and to compare its effects with the available standard drug, diclofenac sodium in mic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9fd83893a082bbeb5476c64c1d23649
https://doi.org/10.21203/rs.3.rs-372019/v1

Antidiabetic activity of aqueous extract of Sigesbeckia orientalis (St. Paul’s Wort) in alloxan-induced diabetes model

Autor: Alamgeer Yuchi, Mohammad Saleem, Sobia Yousaf, Muhammad Asif, Rizwan Ullah Khan, Memoona Zafar, Malik Saadullah

Publikováno v: Brazilian Journal of Pharmaceutical Sciences; Vol. 55 (2019); e18408
Brazilian Journal of Pharmaceutical Sciences; v. 55 (2019); e18408
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP
Brazilian Journal of Pharmaceutical Sciences, Vol 55 (2019)

The current study evaluated antidiabetic and antihyperlipidemic activities of aqueous extract of Sigesbeckia orientalis L. (St. Paul’s Wort) (AESO) in an alloxan-induced diabetic rat model. Following OECD guidelines safe doses of AESO were assessed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03fcfa9ffff6c3bc1169018a2f5a6d72
https://www.revistas.usp.br/bjps/article/view/181104

Chemical and pharmacological comparison of modern and traditional dosage forms of Joshanda

Autor: Ejaz Ali, Nadeem Irfan Bukhari, Khalid Hussain, Surriya Naheed, Naureen Shehzadi, Shaista Qamar, Sajida Parveen, Alamgeer Yuchi, Abida Latif

Publikováno v: Natural product research. 33(6)

Recently, a traditional remedy (Joshanda) has been replaced largely by modern ready-to-use dosage forms, which have not been compared to the original remedy. Therefore, the present study aimed to compare a number of modern dosage forms with tradition

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963ae6ebf516757af0b603452c3aab91
https://pubmed.ncbi.nlm.nih.gov/29224382

Novel acetamide derivatives of 2-aminobenzimidazole prevent inflammatory arthritis in rats via suppression of pro-inflammatory mediators.

Autor: Zubair, Aymun Madni, Malik, Muhammad Nasir Hayat, Younis, Waqas, Malik, Muhammad Atif Hayat, Jahan, Shah, Ahmed, Ishtiaq, Yuchi, Alamgeer, Mushtaq, Muhammad Naveed, Tahir, Romeeza, Sarwar, Muhammad Bilal, Roman, Muhammad, Khan, Ayaz Ali, Tahir, Muhammad Nouman, Khan, Muhammad Tariq, Kharl, Hafiz Amir Ali, Kamran, Gagun, Albegali, Abdullah Abdo, Imran, Ali

Publikováno v: Inflammopharmacology; Jun2022, Vol. 30 Issue 3, p1005-1019, 15p