Zobrazeno 1 - 10
of 25
pro vyhledávání: '"aineenvaihduntahäiriöt"'
Autor:
Eero A. Haapala, Tuomo Tompuri, Niina Lintu, Anna Viitasalo, Kai Savonen, Timo A. Lakka, Jari A. Laukkanen
Publikováno v:
Journal of Science and Medicine in Sport. 25:923-929
Objectives Cardiorespiratory fitness (CRF) has been inversely associated with risk of cardiometabolic diseases. However, there are no studies comparing the independent associations of CRF scaled by body size and composition using different approaches
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d4b6b3f9c0b3af43af5e495dbfb7ea5
https://doi.org/10.1016/j.jsams.2022.08.002
https://doi.org/10.1016/j.jsams.2022.08.002
Autor:
Yuan Zhang, Yuting Liu, Xiaowei Liu, Xinmeng Yuan, Mengqi Xiang, Jingjing Liu, Liumei Zhang, Shouqian Zhu, Jiao Lu, Qiang Tang, Sulin Cheng
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-13
Objective. Nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2DM) commonly coexist and act synergistically to drive adverse clinical outcomes. This study is aimed at investigating the effects of exercise intervention and oral hypoglycaem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::136771ef3f04aea01fd3e3038520e707
https://doi.org/10.1155/2022/2297268
https://doi.org/10.1155/2022/2297268
Autor:
Jari E. Karppinen, Timo Törmäkangas, Urho M. Kujala, Sarianna Sipilä, Jari Laukkanen, Pauliina Aukee, Vuokko Kovanen, Eija K. Laakkonen
Publikováno v:
European Journal of Preventive Cardiology. 29:1448-1459
Aims We studied the changes in the circulating metabolome and their relation to the menopausal hormonal shift in 17β-oestradiol and follicle-stimulating hormone levels among women transitioning from perimenopause to early postmenopause. Methods and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c990fbdb41b98005f69fed8fcfbf83e4
https://doi.org/10.1093/eurjpc/zwac060
https://doi.org/10.1093/eurjpc/zwac060
Autor:
Anastasiia Driuchina, Jukka Hintikka, Marko Lehtonen, Pekka Keski-Rahkonen, Thomas O’Connell, Risto Juvonen, Juho Kuula, Antti Hakkarainen, Jari A. Laukkanen, Elina Mäkinen, Sanna Lensu, Kirsi H. Pietiläinen, Satu Pekkala
Publikováno v:
mBio. 14
Numerous studies have described specific metabolites as biomarkers ofsevere liver diseases, but very few have measured gut microbiota (GM)-produced metab-olites in fatty liver disease. We aimed atfinding GM signatures and metabolite markersin plasma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171801f9d302d7179248aa89680cb677
https://doi.org/10.1128/mbio.02663-22
https://doi.org/10.1128/mbio.02663-22
Autor:
Helena A. K. Lapatto, Minna Kuusela, Aino Heikkinen, Maheswary Muniandy, Birgitta W. van der Kolk, Swetha Gopalakrishnan, Noora Pöllänen, Martin Sandvik, Mark S. Schmidt, Sini Heinonen, Sina Saari, Juho Kuula, Antti Hakkarainen, Janne Tampio, Tuure Saarinen, Marja-Riitta Taskinen, Nina Lundbom, Per-Henrik Groop, Marja Tiirola, Pekka Katajisto, Marko Lehtonen, Charles Brenner, Jaakko Kaprio, Satu Pekkala, Miina Ollikainen, Kirsi H. Pietiläinen, Eija Pirinen
Publikováno v:
Science Advances. 9
Nicotinamide adenine dinucleotide (NAD + ) precursor nicotinamide riboside (NR) has emerged as a promising compound to improve obesity-associated mitochondrial dysfunction and metabolic syndrome in mice. However, most short-term clinical trials condu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c27e77084e80cfbc69cf84d2d47840e
https://doi.org/10.1126/sciadv.add5163
https://doi.org/10.1126/sciadv.add5163
Autor:
Marc Beltrà, Noora Pöllänen, Claudia Fornelli, Kialiina Tonttila, Myriam Y. Hsu, Sandra Zampieri, Lucia Moletta, Samantha Corrà, Paolo E. Porporato, Riikka Kivelä, Carlo Viscomi, Marco Sandri, Juha J. Hulmi, Roberta Sartori, Eija Pirinen, Fabio Penna
Cachexia is a debilitating wasting syndrome and highly prevalent comorbidity in cancer patients. It manifests especially with energy and mitochondrial metabolism aberrations that promote tissue wasting. We recently identified nicotinamide adenine din
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d113a91aadefecf099a81f5e89252c
https://hdl.handle.net/11577/3474380
https://hdl.handle.net/11577/3474380
Autor:
Mia D. Eriksson, Johan G. Eriksson, Päivi Korhonen, Minna K. Salonen, Tuija M. Mikkola, Eero Kajantie, Niko S. Wasenius, Mikaela von Bonsdorff, Hannu Kautiainen, Merja K. Laine
Publikováno v:
Scientific Reports
There is an existing link between two of the most common diseases, obesity and depression. These are both of great public health concern, but little is known about the relationships between the subtypes of these conditions. We hypothesized that non-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11ae3b4a0f55447fafdc2c6274d2f39
http://hdl.handle.net/10138/343557
http://hdl.handle.net/10138/343557
Autor:
Karvinen, Sira, Fachada, Vasco, Sahinaho, Ulla-Maria, Pekkala, Satu, Lautaoja, Juulia H., Mäntyselkä, Sakari, Permi, Perttu, Hulmi, Juha J., Silvennoinen, Mika, Kainulainen, Heikki
Impaired lipid metabolism is a common risk factor underlying several metabolic diseases such as metabolic syndrome and type 2 diabetes. Branched-chain amino acids (BCAAs) that include valine, leucine and isoleucine have been proven to share a role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ad0cf23c7796a22b00ad372641fe7b68
http://hdl.handle.net/10138/343560
http://hdl.handle.net/10138/343560
Autor:
Noerman, Stefania, Klåvus, Anton, Järvelä-Reijonen, Elina, Karhunen, Leila, Auriola, Seppo, Korpela, Riitta, Lappalainen, Raimo, Kujala, Urho M., Puttonen, Sampsa, Kolehmainen, Marjukka, Hanhineva, Kati
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Psychological stress is a suggested risk factor of metabolic disorders, but molecular mediators are not well understood. We investigated the association between the metabolic profiles of fasting plasma and the improvement of psychological well-being
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::262270a3cbd6046a3450fd4b592ad5ec
http://link.springer.com/article/10.1038/s41598-020-59051-x
http://link.springer.com/article/10.1038/s41598-020-59051-x
Autor:
Noora Aho, Mårten Wikström, Vladislav Grigorjev, Vineta Fellman, Vivek Sharma, Janne Purhonen, Artur Osyczka, Robert Ekiert, Jukka Kallijärvi, Rafał Pietras, Katarina Truvé, Jayasimman Rajendran
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications
We previously observed an unexpected fivefold (35 vs. 200 days) difference in the survival of respiratory chain complex III (CIII) deficient Bcs1lp.S78G mice between two congenic backgrounds. Here, we identify a spontaneous homoplasmic mtDNA variant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab0ee8976c7e6c7bef1293e37bef5de9
https://doaj.org/article/3779b9d3fc13415ab6b4e35cb40df347
https://doaj.org/article/3779b9d3fc13415ab6b4e35cb40df347