Zobrazeno 1 - 10
of 191
pro vyhledávání: '"ailanthone"'
Autor:
Lixin Zhao, Yuguang Zhu, Hua Tao, Xiying Chen, Feng Yin, Yingyi Zhang, Jianfeng Qin, Yongyin Huang, Bikun Cai, Yonghao Lin, Jiaxiang Wu, Yu Zhang, Lu Liang, Ao Shen, Xi-Yong Yu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 8, Pp 3543-3560 (2024)
Pulmonary fibrosis poses a significant health threat with very limited therapeutic options available. In this study, we reported the enhanced expression of mesenchymal homobox 1 (MEOX1) in pulmonary fibrosis patients, especially in their fibroblasts
Externí odkaz:
https://doaj.org/article/4b78e458c1284ca9bbbcdc7271785f35
Autor:
Nuolin Shi, Mingjie Li, Xuehui Li, Xinxin Hou, Mingzhu Wang, Zhongya Ni, Shan Lin, Liang Hu, Fuwen Yuan
Publikováno v:
Pharmacological Research - Modern Chinese Medicine, Vol 13, Iss , Pp 100524- (2024)
Introduction: The herbal formula Chouchunpi San (CCPS) is a traditional formula that has been widely used and proven effective in various clinical cancer treatments. However, the mechanism of its anticancer effect remains unclear. This study aims to
Externí odkaz:
https://doaj.org/article/1a6278476a6647cb8eb8ed25fc58f028
Autor:
Shanbo Ma, Xiaodi Guo, Ruisi Han, Qian Meng, Yan Zhang, Wei Quan, Shan Miao, Zhao Yang, Xiaopeng Shi, Siwang Wang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background: Ailanthone, a small compound derived from the bark of Ailanthus altissima (Mill.) Swingle, has several anti-tumour properties. However, the activity and mechanism of ailanthone in colorectal cancer (CRC) remain to be investigated. This st
Externí odkaz:
https://doaj.org/article/dec8a7d3888b4715b982a4c1cd72c5ff
Autor:
Pian Yu, Hui Wei, Kaixuan Li, Shiguo Zhu, Jie Li, Chao Chen, Detian Zhang, Yayun Li, Lei Zhu, Xiaoqing Yi, Nian Liu, Panpan Liu, Shuang Zhao, Xiang Chen, Cong Peng
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-17 (2022)
Abstract Background C-Jun, a critical component of AP-1, exerts essential functions in various tumors, including melanoma, and is believed to be a druggable target for cancer therapy. Unfortunately, no effective c-Jun inhibitors are currently approve
Externí odkaz:
https://doaj.org/article/144a7ae4334e47d9b34a03bcff02b1d1
Publikováno v:
Viruses, Vol 16, Iss 1, p 73 (2023)
Rice stripe disease caused by the rice stripe virus (RSV), which infects many Poaceae species in nature, is one of the most devastating plant viruses in rice that causes enormous losses in production. Ailanthone is one of the typical C20 quassinoids
Externí odkaz:
https://doaj.org/article/73be5970b8c34ade9c028fa9429976fa
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
Introduction: Bone metastasis of breast cancer (BC) is a process in which the disruption of the bone homeostatic microenvironment leads to an increase in osteoclast differentiation. Ailanthus altissima shows an inhibitory effect on osteoclast differe
Externí odkaz:
https://doaj.org/article/95e47e11ea194c429735a41f634dd7a9
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Akademický článek
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Akademický článek
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Autor:
Yawen Zhang, Runze Gong, Yong Liu, Xipeng Sun, Jinrong Liang, Yan Zhou, Yaling Wang, Wenxi Yu, Yonggang Wang, Lina Tang, Aina He, Zan Shen, Yang Yao, Haiyan Hu, Xin Liu, Jianjun Zhang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Osteosarcoma (OS) is the most common primary bone sarcoma, chemoresistance becomes an obstacle to its treatment. Metabolic reprogramming is a hallmark of malignancy, targeting the metabolic pathways might provide a reasonable therapeutic strategy for
Externí odkaz:
https://doaj.org/article/eb2b422a0d1c4998ab65aa2d54e09d2d