The Aedes aegypti Domino Ortholog p400 Regulates Antiviral Exogenous Small Interfering RNA Pathway Activity and ago-2 Expression

Autor: Melanie McFarlane, Floriane Almire, Joy Kean, Claire L. Donald, Alma McDonald, Bryan Wee, Mathilde Lauréti, Margus Varjak, Sandra Terry, Marie Vazeille, Rommel J. Gestuveo, Isabelle Dietrich, Colin Loney, Anna-Bella Failloux, Esther Schnettler, Emilie Pondeville, Alain Kohl

Publikováno v: mSphere, Vol 5, Iss 2 (2020)

ABSTRACT Arboviruses are pathogens of humans and animals. A better understanding of the interactions between these pathogens and the arthropod vectors, such as mosquitoes, that transmit them is necessary to develop novel control measures. A major ant

Externí odkaz: https://doaj.org/article/ad649b2afe974779b5bf0d8d13142e16

Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Inhibits RNA-Mediated Gene Silencing by Targeting Ago-2

Autor: Jing Chen, Xibao Shi, Xiaozhuan Zhang, Li Wang, Jun Luo, Guangxu Xing, Ruiguang Deng, Hong Yang, Jinting Li, Aiping Wang, Gaiping Zhang

Publikováno v: Viruses, Vol 7, Iss 10, Pp 5539-5552 (2015)

Porcine reproductive and respiratory syndrome virus (PRRSV) infection strongly modulates the host’s immune response. The RNA silencing pathway is an intracellular innate response to viral infections. However, it is unknown whether PRRSV interacts w

Externí odkaz: https://doaj.org/article/e2fa229804f749729c533dcca84b59fe

The Aedes aegypti Domino Ortholog p400 Regulates Antiviral Exogenous Small Interfering RNA Pathway Activity and ago-2 Expression

Autor: Isabelle Dietrich, Emilie Pondeville, Floriane Almire, Claire L. Donald, Sandra Terry, Rommel J. Gestuveo, Margus Varjak, Esther Schnettler, Alain Kohl, Marie Vazeille, Melanie McFarlane, Mathilde Laureti, Alma McDonald, Colin Loney, Bryan A. Wee, Joy Kean, Anna-Bella Failloux

Publikováno v: MSphere
MSphere, American Society for Microbiology., 2020, 5 (2), pp.e00081-20. ⟨10.1128/mSphere.00081-20⟩
mSphere, Vol 5, Iss 2 (2020)
mSphere
McFarlane, M, Almire, F, Kean, J, Donald, C L, McDonald, A, Wee, B, Lauréti, M, Varjak, M, Terry, S, Vazeille, M, Gestuveo, R J, Dietrich, I, Loney, C, Failloux, A-B, Schnettler, E, Pondeville, E & Kohl, A 2020, ' The Aedes aegypti Domino Ortholog p400 Regulates Antiviral Exogenous Small Interfering RNA Pathway Activity and ago-2 Expression ', mSphere, vol. 5, no. 2 . https://doi.org/10.1128/mSphere.00081-20
mSphere, Vol 5, Iss 2, p e00081-20 (2020)
MSphere, 2020, 5 (2), pp.e00081-20. ⟨10.1128/mSphere.00081-20⟩

Female Aedes aegypti mosquitoes are vectors of human-infecting arthropod-borne viruses (arboviruses). In recent decades, the incidence of arthropod-borne viral infections has grown dramatically. Vector competence is influenced by many factors, includ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c627b92874c5497fb12f05c65cd42d7
https://hal-pasteur.archives-ouvertes.fr/pasteur-02651768/document

A viral protein restricts Drosophila RNAi immunity by regulating Argonaute activity and stability

Autor: Craig H. Kerr, Kathy H. Li, John D. Gross, Peter V. Lidsky, Arabinda Nayak, Brianna M. Rivera, Dong Young Kim, Judith Frydman, Michael J. Trnka, Eric Jan, Alma L. Burlingame, David J. Stanley, Raul Andino

Publikováno v: Cell host & microbe, vol 24, iss 4

Summary The dicistrovirus, Cricket paralysis virus (CrPV) encodes an RNA interference (RNAi) suppressor, 1A, which modulates viral virulence. Using the Drosophila model, we combined structural, biochemical, and virological approaches to elucidate the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22bbe9a164693cb974c2fd586e082944
https://europepmc.org/articles/PMC6450077/

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