Naïve T-cell decline is a significant contributor to expression changes in ageing blood

Autor: Cameron Fraser, Brady M. Owen

Publikováno v: Frontiers in Aging, Vol 5 (2024)

No clear consensus has emerged from the literature on the gene expression changes that occur in human whole blood with age. In this study we compared whole blood ageing genes from the published literature with data on gene specificity for leukocyte s

Externí odkaz: https://doaj.org/article/edb62e686d7247cdb178c49f9537a2c9

A catalogue of omics biological ageing clocks reveals substantial commonality and associations with disease risk

Autor: Macdonald-Dunlop, Erin, Taba, Nele, Klarić, Lucija, Frkatović, Azra, Walker, Rosie, Hayward, Caroline, Esko, Tõnu, Haley, Chris, Fischer, Krista, Wilson, James F., Joshi, Peter K.

Publikováno v: Macdonald-Dunlop, E, Taba, N, Klarić, L, Frkatović, A, Walker, R, Hayward, C, Esko, T, Haley, C, Fischer, K, Wilson, J F & Joshi, P K 2022, ' A catalogue of omics biological ageing clocks reveals substantial commonality and associations with disease risk ', Aging, vol. 14, no. 2, pp. 623-659 . https://doi.org/10.18632/aging.203847

Biological age (BA), a measure of functional capacity and prognostic of health outcomes that discriminates between individuals of the same chronological age (chronAge), has been estimated using a variety of biomarkers. Previous comparative studies ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c8856e7631d8d5a4327c8a8902d0712
https://pubmed.ncbi.nlm.nih.gov/35073279