Zobrazeno 1 - 10
of 2 007
pro vyhledávání: '"advanced non-small cell lung cancer"'
Autor:
Arnaud Colomb, Benoit Allignet, Mehdi Lamkhioued, Aurelie Swalduz, Lionel Falchero, Aurélie Kienlen, Michaël Duruisseaux, Coralie Moncharmont
Publikováno v:
Radiation Oncology, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract Background Durvalumab, an anti-PD-L1 immune checkpoint inhibitor, after radio-chemotherapy (RCT) has changed the management of locally advanced non-small cell lung cancer (LA NSCLC). A series of retrospective studies have investigated differ
Externí odkaz:
https://doaj.org/article/81af096ad036464ea73b2dd959b41d57
Autor:
Harry Etienne, MD, PhD, Bianca Battilana, MM, Jonathan Spicer, MD, PhD, Raphael S. Werner, MD, MSc, Isabelle Opitz, MD
Publikováno v:
JTCVS Open, Vol 19, Iss , Pp 338-346 (2024)
Externí odkaz:
https://doaj.org/article/e5376bbfd6944675a9c483362a1be0bc
Autor:
Seda Kahraman, Serdar Karakaya, Muhammed Ali Kaplan, Sema Sezgin Goksu, Akin Ozturk, Zehra Sucuoglu Isleyen, Jamshid Hamdard, Sedat Yildirim, Tolga Dogan, Selver Isik, Abdussamet Celebi, Burcu Belen Gulbagci, Nail Paksoy, Mutlu Dogan, Haci Mehmet Turk, Ahmet Bilici, Ali Murat Tatli, Sinem Akbas, Nedim Turan, Ilhan Hacibekiroglu, Gamze Gokoz Dogu, Adnan Aydiner, Ahmet Taner Sumbul, Serap Akyurek, Merih Yalciner, Ahmet Demirkazik, Pinar Gursoy, Musa Baris Aykan, Elif Sahin, İbrahim Karadag, Osman Kostek, Muhammed Muhiddin Er, Mehmet Artaç, Yakup Duzkopru, Dincer Aydin, Deniz Isik, Yusuf Karakas, Saadettin Kilickap, Cihan Erol, Bilgin Demir, Burak Civelek, Yakup Ergun, Muhammed Bulent Akinci, Izzet Dogan, Nuri Karadurmus, Perran Fulden Yumuk, Mehmet Ali Nahit Sendur
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Central nervous system (CNS) metastases can be seen at a rate of 30% in advanced stages for patients with non-small cell lung cancer (NSCLC). Growing evidence indicates the predictive roles of driver gene mutations in the development of brai
Externí odkaz:
https://doaj.org/article/dfd4fc84465f4b4985707fa241e217b7
Autor:
Dae-Ho Choi, MD, Miso Kim, MD, PhD, Young Saing Kim, MD, PhD, Keon Uk Park, MD, PhD, Jang Ho Cho, MD, PhD, Hongsik Kim, MD, PhD, Ki Hyeong Lee, MD, PhD, Heejoon Ahn, MD, PhD, Il-Hwan Kim, MD, PhD, Kyung-Hee Lee, MD, PhD, Gyeong-Won Lee, MD, PhD, Seong Yoon Yi, MD, PhD, Beung chul Ahn, MD, PhD, Min-Young Lee, MD, PhD, Hyun Ae Jung, MD, PhD, Sehhoon Park, MD, PhD, Jong-Mu Sun, MD, PhD, Jin Seok Ahn, MD, PhD, Se-Hoon Lee, MD, PhD, Myung-Ju Ahn, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 12, Pp 100734- (2024)
Introduction: The role of maintenance durvalumab after definitive concurrent chemoradiotherapy (CCRT) in unresectable locally advanced NSCLC with EGFR mutation or ALK translocation remains unclear. We compared the effectiveness of durvalumab maintena
Externí odkaz:
https://doaj.org/article/5adc6e00d2074509b50a281b9eca7f23
Autor:
Hong Zhu, Yi Xu, Huiquan Gao, Xingwen Fan, Ming Fan, Kuaile Zhao, Huanjun Yang, Zhengfei Zhu, Kailiang Wu
Publikováno v:
Cancer Medicine, Vol 13, Iss 15, Pp n/a-n/a (2024)
Abstract Background There was limited research data on large‐scale locally advanced non‐small cell lung cancer (LA‐NSCLC) radical radiotherapy (RT) reported in China. This study examined overall survival (OS), progression‐free survival (PFS),
Externí odkaz:
https://doaj.org/article/7c223d54176e456290031811585c0b86
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Lung cancer stands as a malignant neoplasm bearing the highest burden of morbidity and mortality within the elderly population on a global scale. Among the lung cancer subtypes, non-small cell lung cancer (NSCLC) prevails as the most prevalent. As ag
Externí odkaz:
https://doaj.org/article/a5a7498dbdb743bab44c5a92245fea8c
Autor:
Yalun Li, Liyan Ji, Yingqian Zhang, Jiexin Zhang, Alexandre Reuben, Hao Zeng, Qin Huang, Qi Wei, Sihan Tan, Xuefeng Xia, Weimin Li, Jianjun Zhang, Panwen Tian
Publikováno v:
MedComm, Vol 5, Iss 6, Pp n/a-n/a (2024)
Abstract Tumor mutational burden (TMB) and T‐cell receptor (TCR) might predict the response to immunotherapy in patients with non–small cell lung cancer (NSCLC). However, the predictive value of the combination of TMB and TCR was not clear. Targe
Externí odkaz:
https://doaj.org/article/5b88ca7b94804c7898390563f206f409
Autor:
Cam Phuong Pham, Thi Thai Hoa Nguyen, Anh Tu Do, Tuan Khoi Nguyen, Thi Anh Thu Hoang, Tuan Anh Le, Dinh Thy Hao Vuong, Dac Nhan Tam Nguyen, Van Khiem Dang, Thi Oanh Nguyen, Van Luan Pham, Minh Hai Nguyen, Thi Huyen Trang Vo, Hung Kien Do, Ha Thanh Vu, Thi Thuy Hang Nguyen, Van Thai Pham, Le Huy Trinh, Khac Dung Nguyen, Hoang Gia Nguyen, Cong Minh Truong, Tran Minh Chau Pham, Thi Bich Phuong Nguyen
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background This study aimed to evaluate the efficacy and side effects of first-line afatinib treatment in a real-world setting in Vietnam. Methods This retrospective study was conducted across nine hospitals in Vietnam. Advanced epidermal gr
Externí odkaz:
https://doaj.org/article/36865a07e0674f89ab90acac425e34cb
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background CCRT is presently the standard treatment for LA-NSCLC. RP is one of the main obstacles to the completion of thoracic radiation therapy, resulting in limited survival benefits in NSCLC patients. This research aims to explore the ro
Externí odkaz:
https://doaj.org/article/7b4ebcf357f6402fbde6cb3e51fdd981
Publikováno v:
Cancer Biology & Medicine, Vol 20, Iss 12, Pp 1035-1046 (2023)
Maintenance immunotherapy after concurrent chemoradiotherapy remains the standard therapeutic approach in patients with unresectable locally advanced non-small cell lung cancer (LA-NSCLC). The efficacy of pembrolizumab without chemotherapy in stage I
Externí odkaz:
https://doaj.org/article/5fe4afed98eb4d04b203a999fdfdcece