Zobrazeno 1 - 10
of 101
pro vyhledávání: '"adoptive cell transfer therapy"'
Autor:
Cheng Wei, Xin Huang, Tianlong Xu, Yinan Fang, Fabao Wang, Qiaolin He, Peiyuan Zhang, Qianjin Yu, Ying Zhang, Binjiao Zheng, Yue Gao, Yongping Chen, Qichuan Zhuge, Ai Zhao, Jimin Gao, Jinhong Jiang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionT cell Antigen Coupler (TAC) T cells harness all signaling subunits of endogenous T cell receptor (TCR) to trigger T-cell activation and tumor cell lysis, with minimal release of cytokines. Some of the major obstacles to cellular immunoth
Externí odkaz:
https://doaj.org/article/a60b92ced82045508b4898d4ffe2b58d
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-4 (2024)
Abstract The efficacy of Adoptive Cell Transfer Therapy (ACT) in combating hematological tumors has been well-documented, yet its application to solid tumors faces formidable hurdles, chief among them being the suboptimal therapeutic response and the
Externí odkaz:
https://doaj.org/article/46bfb5f689d04f6da1edf6662e98ba37
Autor:
Odd L. Gammelgaard, Mikkel G. Terp, Alexei F. Kirkin, Simone Johansen, Sofie Traynor, Henriette Vever, Per Guldberg, Annette R. Kodahl, Morten F. Gjerstorff, Henrik J. Ditzel
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-16 (2024)
Abstract Background Adoptive cell transfer cancer immunotherapy holds promise for treating disseminated disease, yet generating sufficient numbers of lymphocytes with anti-cancer activity against diverse specificities remains a major challenge. We re
Externí odkaz:
https://doaj.org/article/b15051babf3e4694bceb90e2ee16d652
Publikováno v:
Biology, Vol 13, Iss 5, p 307 (2024)
Cancer immune evasion represents a leading hallmark of cancer, posing a significant obstacle to the development of successful anticancer therapies. However, the landscape of cancer treatment has significantly evolved, transitioning into the era of im
Externí odkaz:
https://doaj.org/article/74c5b7dd0fa34af9b6e0371bd9e0105a
Autor:
Wenyi Yan, Louisa S. Chard Dunmall, Nicholas R. Lemoine, Yaohe Wang, Yafeng Wang, Pengju Wang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
γδ T cells, a specialized subset of T lymphocytes, have garnered significant attention within the realm of cancer immunotherapy. Operating at the nexus between adaptive and innate immunological paradigms, these cells showcase a profound tumor disce
Externí odkaz:
https://doaj.org/article/e0911c4bb9db48e9ad80c49c2fe0fdb4
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Autor:
Zhi-hong Duan, Zi-long Wei
Publikováno v:
Journal of Integrative Neuroscience, Vol 22, Iss 5, p 118 (2023)
Although some progress has been made in tumor treatment, gliomas remain one of the tumors that can still seriously threaten human life and health. Due to the particularity of the immune microenvironment of the central nervous system and the strong in
Externí odkaz:
https://doaj.org/article/6a7552768ed3478c9d10c52b88382dd3
Autor:
Faizan Ahmad
Publikováno v:
Biomedical and Biotechnology Research Journal, Vol 4, Iss 3, Pp 179-185 (2020)
Chimeric antigen receptor (CAR) T-cell therapy is an advanced personalized immunotherapy used in the treatment of many cancers. Basically, an immunotherapy uses the body's own immune system to detect and destroy the cancerous cells. The isolated T-ce
Externí odkaz:
https://doaj.org/article/4313d0790d804d6f848ad44cc1e1e6c3
Publikováno v:
Medicine in Drug Discovery, Vol 13, Iss , Pp 100116- (2022)
Cancer immunotherapy is becoming an important option for treating patients with cancer in clinic. Given the heterogeneity of tumors between individuals, personalized cancer immunotherapy is the most promising one. Tremendous progresses have been achi
Externí odkaz:
https://doaj.org/article/01486e77261441af9891cdd99f7a0647