Zobrazeno 1 - 10
of 131
pro vyhledávání: '"adipocyte progenitors"'
Publikováno v:
Physiological Reports, Vol 11, Iss 4, Pp n/a-n/a (2023)
Abstract Brown adipose tissue (BAT) has in recent times been rediscovered in adult humans, and together with work from preclinical models, has shown to have the potential of providing a variety of positive metabolic benefits. These include lower plas
Externí odkaz:
https://doaj.org/article/8c9ad0f7652a408784959ad2dbaa3c41
Autor:
Muhammad Bilal, Allah Nawaz, Tomonobu Kado, Muhammad Rahil Aslam, Yoshiko Igarashi, Ayumi Nishimura, Yoshiyuki Watanabe, Takahide Kuwano, Jianhui Liu, Hiroyuki Miwa, Takumi Era, Koichi Ikuta, Johji Imura, Kunimasa Yagi, Takashi Nakagawa, Shiho Fujisaka, Kazuyuki Tobe
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101328- (2021)
Objective: Expansion of adipose tissue during obesity through the recruitment of newly generated adipocytes (hyperplasia) is metabolically healthy, whereas that through the enlargement of pre-existing adipocytes (hypertrophy) leads to metabolic compl
Externí odkaz:
https://doaj.org/article/26f597ca874e42599c41c8fa0a7b32a1
Autor:
Allah Nawaz, Kazuyuki Tobe
Publikováno v:
Journal of Diabetes Investigation, Vol 10, Iss 6, Pp 1394-1400 (2019)
Abstract Adipose tissue (AT) is composed not only of adipocytes, but also of macrophages, endothelial cells and preadipocytes. Macrophages are an important component of AT, and are involved in tissue homeostasis, tissue repair and fibrosis. AT‐resi
Externí odkaz:
https://doaj.org/article/b4b89c2c15a1434286a2913619e38938
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2020)
Brown and brown-like adipocytes (BAs) are promising cell targets to counteract obesity thanks to their potential to drain and oxidize circulating glucose and triglycerides. However, the scarcity of BAs in human adults is a major limitation for energy
Externí odkaz:
https://doaj.org/article/788f11c33f814d689c114a3268a3d2b0
Autor:
Irem Bayindir‐Buchhalter, Gretchen Wolff, Sarah Lerch, Tjeerd Sijmonsma, Maximilian Schuster, Jan Gronych, Adrian T Billeter, Rohollah Babaei, Damir Krunic, Lars Ketscher, Nadine Spielmann, Martin Hrabe de Angelis, Jorge L Ruas, Beat P Müller‐Stich, Mathias Heikenwalder, Peter Lichter, Stephan Herzig, Alexandros Vegiopoulos
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 8, Pp 1-18 (2018)
Abstract Most antidiabetic drugs treat disease symptoms rather than adipose tissue dysfunction as a key pathogenic cause in the metabolic syndrome and type 2 diabetes. Pharmacological targeting of adipose tissue through the nuclear receptor PPARg, as
Externí odkaz:
https://doaj.org/article/a4f7620a706d40c1b743c16d6f4e5f05
Publikováno v:
Cells, Vol 9, Iss 4, p 863 (2020)
Adipose tissue (AT) is comprised of a diverse number of cell types, including adipocytes, stromal cells, endothelial cells, and infiltrating leukocytes. Adipose stromal cells (ASCs) are a mixed population containing adipose progenitor cells (APCs) as
Externí odkaz:
https://doaj.org/article/4e178ee48de3414c9e3bd7745c73e99b
Autor:
Jennifer L. Kaplan, Melissa A. Marshall, Chantel C. McSkimming, Daniel B. Harmon, James C. Garmey, Stephanie N. Oldham, Peter Hallowell, Coleen A. McNamara
Publikováno v:
Molecular Metabolism, Vol 4, Iss 11, Pp 779-794 (2015)
Objective: Macrophages are important producers of obesity-induced MCP-1; however, initial obesity-induced increases in MCP-1 production precede M1 macrophage accumulation in visceral adipose tissue (VAT). The initial cellular source of obesity-induce
Externí odkaz:
https://doaj.org/article/da87b27aafea4da5a93e33162a5af5d3
Akademický článek
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Akademický článek
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Autor:
Irem eBayindir, Rohollah eBabaeikelishomi, Silvia eKocanova, Isabel Sofia Sousa, Sarah eLerch, Olaf eHardt, Stefan eWild, Andreas eBosio, Kerstin eBystricky, Stephan eHerzig, Alexandros eVegiopoulos
Publikováno v:
Frontiers in Endocrinology, Vol 6 (2015)
De novo formation of beige/brite adipocytes from progenitor cells contributes to the thermogenic adaptation of adipose tissue and holds great potential for the therapeutic remodeling of fat as a treatment for obesity. Despite the recent identificatio
Externí odkaz:
https://doaj.org/article/505bdafb95214a71adc84bac65bc60fa