Zobrazeno 1 - 10
of 290
pro vyhledávání: '"adil mardinoglu"'
Autor:
Lingqi Meng, Han Jin, Burak Yulug, Ozlem Altay, Xiangyu Li, Lutfu Hanoglu, Seyda Cankaya, Ebru Coskun, Ezgi Idil, Rahim Nogaylar, Ahmet Ozsimsek, Saeed Shoaie, Hasan Turkez, Jens Nielsen, Cheng Zhang, Jan Borén, Mathias Uhlén, Adil Mardinoglu
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-20 (2024)
Abstract Alzheimer’s disease (AD) is a debilitating neurodegenerative disorder with a global impact, yet its pathogenesis remains poorly understood. While age, metabolic abnormalities, and accumulation of neurotoxic substances are potential risk fa
Externí odkaz:
https://doaj.org/article/39a09c10d79c4cb7af897566df85c1bc
Autor:
Sunjae Lee, Victoria Meslier, Gholamreza Bidkhori, Fernando Garcia-Guevara, Lucie Etienne-Mesmin, Frederick Clasen, Junseok Park, Florian Plaza Oñate, Haizhuang Cai, Emmanuelle Le Chatelier, Nicolas Pons, Marcela Pereira, Maike Seifert, Fredrik Boulund, Lars Engstrand, Doheon Lee, Gordon Proctor, Adil Mardinoglu, Stéphanie Blanquet-Diot, David Moyes, Mathieu Almeida, S. Dusko Ehrlich, Mathias Uhlen, Saeed Shoaie
Publikováno v:
npj Biofilms and Microbiomes, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Species composition of the healthy adult gut microbiota tends to be stable over time. Destabilization of the gut microbiome under the influence of different factors is the main driver of the microbial dysbiosis and subsequent impacts on host
Externí odkaz:
https://doaj.org/article/a887eb4803374d36b77690db31148648
Autor:
Han Jin, Cheng Zhang, Jan Nagenborg, Peter Juhasz, Adele V. Ruder, Cornelis J. J. M. Sikkink, Barend M. E. Mees, Olivia Waring, Judith C. Sluimer, Dietbert Neumann, Pieter Goossens, Marjo M. P. C. Donners, Adil Mardinoglu, Erik A. L. Biessen
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract Background Metabolism is increasingly recognized as a key regulator of the function and phenotype of the primary cellular constituents of the atherosclerotic vascular wall, including endothelial cells, smooth muscle cells, and inflammatory c
Externí odkaz:
https://doaj.org/article/abf30882fa56414492f4965ea2f6957e
Autor:
Julio Baudin, Julia Hernandez-Baixauli, Jordi Romero-Giménez, Hong Yang, Francisca Mulero, Francesc Puiggròs, Adil Mardinoglu, Lluís Arola, Antoni Caimari
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 179, Iss , Pp 117326- (2024)
Many women have sought alternative therapies to address menopause. Recently, a multi-ingredient supplement (MIS) containing L-histidine, L-carnosine, L-serine, and L-cysteine has been shown to be effective at ameliorating hepatic steatosis (HS) in ov
Externí odkaz:
https://doaj.org/article/3b7e928228d2435982ac05747dbdf043
Autor:
Elyas Mohammadi, Samira Dashti, Neda Shafizade, Han Jin, Cheng Zhang, Simon Lam, Mojtaba Tahmoorespur, Adil Mardinoglu, Mohammad Hadi Sekhavati
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Immunomodulatory peptides, while exhibiting potential antimicrobial, antifungal, and/or antiviral properties, can play a role in stimulating or suppressing the immune system, especially in pathological conditions like breast cancer (BC). Thu
Externí odkaz:
https://doaj.org/article/b1334d5444d848898de2633f202bf587
Autor:
Sarah Snanoudj, Céline Derambure, Cheng Zhang, Nguyen Thi Hai Yen, Céline Lesueur, Sophie Coutant, Lénaïg Abily-Donval, Stéphane Marret, Hong Yang, Adil Mardinoglu, Soumeya Bekri, Abdellah Tebani
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34357- (2024)
Fabry disease (FD) is an X-linked lysosomal disease caused by an enzyme deficiency of alpha-galactosidase A (α-gal A). This deficiency leads to the accumulation of glycosphingolipids in lysosomes, resulting in a range of clinical symptoms. The compl
Externí odkaz:
https://doaj.org/article/98f4d6744b8c48ab8fb74841335491bb
Autor:
Bengisu Guner Yilmaz, Ozlem Akgun-Dogan, Ozkan Ozdemir, Bayram Yuksel, Ozden Hatirnaz Ng, Kaya Bilguvar, Beril Ay, Gulsah Sebnem Ozkose, Eylul Aydin, Ayca Yigit, Aybike Bulut, Fatma Nisa Esen, Serdar Beken, Selma Aktas, Atalay Demirel, Baran Cengiz Arcagok, Ebru Kazanci, İbrahim Bingol, Ozge Umur, Guntulu Sik, Ugur Isik, Melike Ersoy, Ayse Korkmaz, Agop Citak, Adil Mardinoglu, Ugur Ozbek, Yasemin Alanay
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
IntroductionRare and ultra-rare genetic conditions significantly contribute to infant morbidity and mortality, often presenting with atypical features and genetic heterogeneity that complicate management. Rapid genome sequencing (RGS) offers a timely
Externí odkaz:
https://doaj.org/article/09a390dd2ca34c80943a1799cdb86d67
Autor:
Atakan Burak Ceyhan, Mehmet Ozcan, Woonghee Kim, Xiangyu Li, Ozlem Altay, Cheng Zhang, Adil Mardinoglu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116920- (2024)
Sarcopenia is a major public health concern among older adults, leading to disabilities, falls, fractures, and mortality. This study aimed to elucidate the pathophysiological mechanisms of sarcopenia and identify potential therapeutic targets using s
Externí odkaz:
https://doaj.org/article/b853d1d5a56641ae98a857fd8d4fbd9f
Autor:
Ali Kaynar, Woonghee Kim, Atakan Burak Ceyhan, Cheng Zhang, Mathias Uhlén, Hasan Turkez, Saeed Shoaie, Adil Mardinoglu
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2237 (2024)
Background/Objectives: Despite current treatments extending the lifespan of Glioblastoma (GBM) patients, the average survival time is around 15–18 months, underscoring the fatality of GBM. This study aims to investigate the impact of sample heterog
Externí odkaz:
https://doaj.org/article/e0cc667902d0427b879ec75ecb0d0a92
Autor:
Han Jin, Cheng Zhang, Martin Zwahlen, Kalle von Feilitzen, Max Karlsson, Mengnan Shi, Meng Yuan, Xiya Song, Xiangyu Li, Hong Yang, Hasan Turkez, Linn Fagerberg, Mathias Uhlén, Adil Mardinoglu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Cell lines are valuable resources as model for human biology and translational medicine. It is thus important to explore the concordance between the expression in various cell lines vis-à-vis human native and disease tissues. In this study,
Externí odkaz:
https://doaj.org/article/981f4ee29ebc40c8b7248086e28ad99a