Zobrazeno 1 - 10
of 44
pro vyhledávání: '"adenosine receptor A2B"'
Autor:
Kristian-Christos Ngamsri, Christoph Jans, Rizki A. Putri, Katharina Schindler, Jutta Gamper-Tsigaras, Claudia Eggstein, David Köhler, Franziska M. Konrad
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Our previous studies revealed a pivotal role of the chemokine stromal cell-derived factor (SDF)-1 and its receptors CXCR4 and CXCR7 on migratory behavior of polymorphonuclear granulocytes (PMNs) in pulmonary inflammation. Thereby, the SDF-1-CXCR4/CXC
Externí odkaz:
https://doaj.org/article/17897d4a7c6c493099f754d04a1d2840
Autor:
Sabrina Taliani, Federico Da Settimo, Claudia Martini, Sonia Laneri, Ettore Novellino, Giovanni Greco
Publikováno v:
Molecules, Vol 25, Iss 10, p 2331 (2020)
Several indole derivatives have been disclosed by our research groups that have been collaborating for nearly 25 years. The results of our investigations led to a variety of molecules binding selectively to different pharmacological targets, specific
Externí odkaz:
https://doaj.org/article/17d219ede2874b3a800167781a126827
Akademický článek
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Autor:
Suneil K. Koliwad, Rachel T. Cheang, Frederic Woodward Hopf, Xiaoyi Yuan, Allison W. Xu, Matthew T Maier, Sharon M. Louie, Scott A. Wegner, Anna Vilhelmsson, Ernie Yulyaningsih, Maria Ibars, Daniel K. Nomura, Holger K. Eltzschig, Luz Perez
Publikováno v:
Am J Physiol Endocrinol Metab
Excessive alcohol consumption, including binge drinking, is a common cause of fatty liver disease. Binge drinking rapidly induces hepatic steatosis, an early step in the pathogenesis of chronic liver injury. Despite its prevalence, the process by whi
Publikováno v:
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Vol 8 (2021)
Frontiers in Molecular Biosciences, Vol 8 (2021)
Adenosinereceptor A2B (ADORA2B) encodes a protein belonging to the G protein–coupled receptor superfamily. Abnormal expression of ADORA2B may play a pathophysiological role in some human cancers. We investigated whether ADORA2B is a potential diagn
Autor:
Celine Chen, Joseph F. Urban, Trinity L. Perry, Carol G. Chitko-McKown, Ethiopia Beshah, Harry D. Dawson, Lumei Cheung, Allen Smith
Publikováno v:
Developmental & Comparative Immunology. 98:20-33
We previously demonstrated that the most bioactive vitamin A metabolite, all-trans retinoic acid (ATRA), increased T helper 2-associated responses induced in pigs by infection with the parasitic nematode Ascaris suum We also showed that ATRA potentia
Publikováno v:
Mediators of Inflammation, Vol 2020 (2020)
Necrotizing enterocolitis (NEC) is a lethal gastrointestinal tract disease that occurs in premature infants. Adenosine receptor A2B (A2BR) regulates the inflammation cytokine secretion and immune cell infiltration in the colonic pathophysiology condi
Publikováno v:
JHEP Reports, Vol 2, Iss 6, Pp 100165-(2020)
JHEP Reports
JHEP Reports
Summary: Extracellular nucleotides, including ATP, are essential regulators of liver function and serve as danger signals that trigger inflammation upon injury. Ectonucleotidases, which are expressed by liver-resident cells and recruited immune cells
Autor:
Aileen Hochhäuser, Camilla Scheele, Christian Dani, Thorsten Gnad, Frank Suhr, Saskia Haufs-Brusberg, Volodymyr Tsvilovskyy, Peter Brust, Arnau Cordomí, Minna Lahesmaa, Wilhelm Bloch, Markku Taittonen, Matthias Blüher, Mathias Kranz, Leonardo Pardo, Daniela Wenzel, Holger K. Eltzschig, Laia Reverte-Salisa, Francesca Copperi, Alexander Pfeifer, Gemma Navarro, Rafael Franco, Tarja Niemi, Jennifer Naumann, Pirjo Nuutila, Winnie Deuther-Conrad, Christian Brinkmann, Bernd K. Fleischmann, Naja Z. Jespersen, Joern Rittweger, Kirsi A. Virtanen
Publikováno v:
Cell Metabolism 32(2020), 56-70
Cell Metab
Cell Metab
The combination of aging populations with the obesity pandemic results in an alarming rise in non-communicable diseases. Here, we show that the enigmatic adenosine A2B receptor (A2B) is abundantly expressed in skeletal muscle (SKM) as well as brown a
Autor:
Ettore Novellino, Claudia Martini, Sonia Laneri, Giovanni Greco, Sabrina Taliani, Federico Da Settimo
Publikováno v:
Molecules
Molecules, Vol 25, Iss 2331, p 2331 (2020)
Molecules, Vol 25, Iss 2331, p 2331 (2020)
Several indole derivatives have been disclosed by our research groups that have been collaborating for nearly 25 years. The results of our investigations led to a variety of molecules binding selectively to different pharmacological targets, specific