Zobrazeno 1 - 10
of 1 269
pro vyhledávání: '"adenosine monophosphate - activated protein kinase"'
Publikováno v:
Linchuang shenzangbing zazhi, Vol 24, Iss 11, Pp 930-937 (2024)
Objective To explore the effect and mechanism of astragalin （AG） in alleviating renal injury in diabetic kidney disease(DKD). Methods db/m and db/db mice aged 16 weeks were randomized into four groups of db/m, db/m+AG （5 mg/kg）, db/db and db/
Externí odkaz:
https://doaj.org/article/c845890ef9bd49efa3441fdf6ced5d0b
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Liver Kinase B1 (LKB1), encoded by Serine-Threonine Kinase 11 (STK11), is a master kinase that regulates cell migration, polarity, proliferation, and metabolism through downstream adenosine monophosphate-activated protein kinase (AMPK) and A
Externí odkaz:
https://doaj.org/article/177eccc9e3384d40af0f4e11a5e253a0
Publikováno v:
eFood, Vol 5, Iss 5, Pp n/a-n/a (2024)
Abstract Black raspberry (Rubus occidentalis) shows beneficial health effects, such as antioxidant, anti‐inflammatory, chemopreventive, antiproliferative, and antihyperglycemic activities. The present study investigated the antihyperglycemic activi
Externí odkaz:
https://doaj.org/article/fd8a8e26fa5d4797840f5413ade91bf4
Autor:
Yang Sun, Dengyue Xu, Weidong Yang, Hongquan Zhang, Yi Su, Bin Gao, Xiaowei Zou, Yiming Zhong, Huanwei Sun, Liangbi Xiang
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-10 (2023)
Abstract Background Spinal cord ischemia–reperfusion injury (SCII) is a catastrophic event, which can cause paraplegia in severe cases. In the reperfusion stage, oxidative stress was up-regulated, which aggravated the injury and apoptosis of neuron
Externí odkaz:
https://doaj.org/article/a40a71c19c574b4e9f6651678ef5e0ab
Publikováno v:
Xiehe Yixue Zazhi, Vol 14, Iss 3, Pp 543-552 (2023)
Objective To investigate the mechanism of Vaspin in improving the pancreatic beta cell function in type 2 diabetic (T2DM) rats. Methods The diabetic rat model was established by feeding high-fat and high-sugar diet combined with intraperitoneal injec
Externí odkaz:
https://doaj.org/article/5e880b720fe244a59882cf52233ed6fd
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 59 (2023)
Abstract This study aimed to investigate the role and signaling pathways of β3-AR in myocardial ischemia/reperfusion (I/R) injury, which is one of the leading causes of death worldwide. 47 male rats were randomly divided into two main groups to eval
Externí odkaz:
https://doaj.org/article/68a0197ecab9469b9cd47572d151e2a8
Autor:
Jin-Yun Zhao, Xiao-Long Sheng, Cheng-Jun Li, Tian Qin, Run-Dong He, Guo-Yu Dai, Yong Cao, Hong-Bin Lu, Chun-Yue Duan, Jian-Zhong Hu
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 7, Pp 1553-1562 (2023)
Treatment with metformin can lead to the recovery of pleiotropic biological activities after spinal cord injury. However, its effect on spinal cord injury in aged mice remains unclear. Considering the essential role of angiogenesis during the regener
Externí odkaz:
https://doaj.org/article/fe5f7ba85664418c92a45648ce18dd01
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-16 (2022)
Abstract Background Oxidative stress-caused damage to the retinal pigment epithelium (RPE) underlies the onset and progression of age-related macular degeneration (AMD). Impaired mitochondrial biogenesis sensitizes RPE cells to mitochondrial dysfunct
Externí odkaz:
https://doaj.org/article/48109572ce664b6faaf4b3ce3d2919e0
Publikováno v:
Lipids in Health and Disease, Vol 21, Iss 1, Pp 1-14 (2022)
Abstract Background Hepatic caveolin-1 (CAV1) is reduced in cholesterol gallstone disease (CGD). Mice with CAV1 deficiency were prone to develop CGD. However, it remains unknown whether restored hepatic CAV1 expression prevents the development of CGD
Externí odkaz:
https://doaj.org/article/50f63678a41d442d9c05ac527eb1d811
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