Zobrazeno 1 - 10
of 49
pro vyhledávání: '"adeno-associated virus (AAV) vector"'
Autor:
Ping Guo, Ting Zhang, Aiping Lu, Chiyo Shiota, Matthieu Huard, Kaitlyn E. Whitney, Johnny Huard
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 28, Iss , Pp 355-365 (2023)
Endogenous reprogramming of pancreas-derived non-beta cells into insulin-producing cells is a promising approach to treat type 1 diabetes (T1D). One strategy that has yet to be explored is the specific delivery of insulin-producing essential genes, P
Externí odkaz:
https://doaj.org/article/071296e252ae4af995370cf9d7ab1b20
Akademický článek
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Autor:
Amira D. Rghei, Laura P. van Lieshout, Benjamin M. McLeod, Yanlong Pei, Jordyn A. Lopes, Nicole Zielinska, Enzo M. Baracuhy, Brenna A. Y. Stevens, Sylvia P. Thomas, Jacob G. E. Yates, Bryce M. Warner, Darwyn Kobasa, Hugues Fausther-Bovendo, Gary P. Kobinger, Khalil Karimi, Brad Thompson, Byram W. Bridle, Leonardo Susta, Sarah K. Wootton
Publikováno v:
Biomedicines, Vol 9, Iss 9, p 1186 (2021)
Adeno-associated virus (AAV) vector mediated expression of therapeutic monoclonal antibodies is an alternative strategy to traditional vaccination to generate immunity in immunosuppressed or immunosenescent individuals. In this study, we vectorized a
Externí odkaz:
https://doaj.org/article/f323e697c3344c79998e1eb3bd389d59
Publikováno v:
Viruses, Vol 12, Iss 11, p 1266 (2020)
Jaagsiekte sheep retrovirus (JSRV) induces tumors in the distal airways of sheep and goats. A putative intragenic enhancer, termed JE, localized to the 3′ end of the JSRV env gene, has been previously described. Herein we provide further evidence t
Externí odkaz:
https://doaj.org/article/e8c530e103754abdb9486b6e8515f115
Akademický článek
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Publikováno v:
Vaccines, Vol 6, Iss 3, p 35 (2018)
Hemagglutinin (HA) of influenza virus is a major target for vaccines. HA initiates the internalization of the virus into the host cell by binding to host sialic acid receptors; therefore, inhibition of HA can significantly prevent influenza virus inf
Externí odkaz:
https://doaj.org/article/73299d38a34441b6852465b72ceb1276
Akademický článek
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Autor:
Hitoshi Osaka, Akihiko Miyauchi, Yoshiyuki Onuki, Tetsuo Kubota, Karin Kojima, Hiroaki Mizukami, Shin-ichi Muramatsu, Kazuyuki Nakamura, Takanori Yamagata, Takeshi Nakajima, Takahiro Ikeda, Sayaka Ono, Naoyuki Taga, Mitsuhiro Kato, Ayumi Matsumoto, Toshihiko Sato
Publikováno v:
Brain
AADC deficiency causes severe motor and intellectual disability as a result of reduced catecholamine levels. Kojima et al. report beneficial effects of gene therapy in six patients with heterogeneous genetic backgrounds. Gene delivery into putamen im
Publikováno v:
Viruses, Vol 12, Iss 1266, p 1266 (2020)
Viruses
Volume 12
Issue 11
Viruses
Volume 12
Issue 11
Jaagsiekte sheep retrovirus (JSRV) induces tumors in the distal airways of sheep and goats. A putative intragenic enhancer, termed JE, localized to the 3&prime
end of the JSRV env gene, has been previously described. Herein we provide further ev
end of the JSRV env gene, has been previously described. Herein we provide further ev
Autor:
Leonardo Susta, Brenna A Y Stevens, Jordyn A. Lopes, Jacob G. E. Yates, Enzo M. Baracuhy, Sarah K. Wootton, Byram W. Bridle, Darwyn Kobasa, Nicole Zielinska, Laura P. van Lieshout, Khalil Karimi, Benjamin M. McLeod, Gary P. Kobinger, Hugues Fausther-Bovendo, Amira D Rghei, Yanlong Pei, Brad Thompson, Bryce M. Warner, Sylvia P. Thomas
Publikováno v:
Biomedicines
Biomedicines, Vol 9, Iss 1186, p 1186 (2021)
Volume 9
Issue 9
Biomedicines, Vol 9, Iss 1186, p 1186 (2021)
Volume 9
Issue 9
Adeno-associated virus (AAV) vector mediated expression of therapeutic monoclonal antibodies is an alternative strategy to traditional vaccination to generate immunity in immunosuppressed or immunosenescent individuals. In this study, we vectorized a