N-Thio-β-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis

Autor: Robert Schnell, Paola Dal Monte, Michael Landreh, Eva Maria Steiner, Martina Cirillo, Carolina Caso, Daria Giacomini, Tomas Bohn Pessatti, Giulia Martelli, Francesco Bisognin

Publikováno v: Cell chemical biology. 28(9)

Summary Effective treatment of tuberculosis is frequently hindered by the emerging antimicrobial resistance of Mycobacterium tuberculosis. The present study evaluates monocyclic β-lactam compounds targeting the mycobacterial cell wall remodeling. No

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::891ad589948e9d024dfdeffeaaf479da
https://pubmed.ncbi.nlm.nih.gov/34215443

Crystal structure of the 1:1 adduct of 2,3-diphenyl-3,4,5,6-tetrahydro-2H-1,3-thiazin-4-one with triphenyltin chloride

Autor: Ryan Fox, Hemant P. Yennawar, Lee J. Silverberg

Publikováno v: Acta Crystallographica Section E: Crystallographic Communications
Acta Crystallographica Section E: Crystallographic Communications, Vol 72, Iss 3, Pp 276-279 (2016)

In the adduct resulting from the reaction of 2,3-diphenyl-3,4,5,6-tetra­hydro-2H-1,3-thia­zin-4-one with tri­phenyl­tin chloride, the three rings of the tri­phenyl­tin group are involved in intra­molecular inter­actions of different types, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb41c295e30e3e7c3049fa4ec11c56c
https://doi.org/10.1107/s2056989016001730

СИНТЕЗ И РЕНТГЕНОСТРУКТУРНЫЙ АНАЛИЗ АДДУКТА ТИОФЕНА В РЕАКЦИИ ДИЛЬСА – АЛЬДЕРА С МАЛЕИНОВЫМ АНГИДРИДОМ // Ученые записки КФУ. Естественные науки 2012 том154 N3

Publikováno v: ELIB18156169-2012-154-3-3

Методом рентгеноструктурного анализа доказано, что структура аддукта реакции Дильса – Альдера между тиофеном и малеиновым ангидридом,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=httpsopenrep::564d6f50bb8b4d25bfe59836e80ac59e
https://openrepository.ru/article?id=688929

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