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pro vyhledávání: '"addiction vulnerability"'
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Publikováno v:
Tobacco Induced Diseases, Vol 17, Iss February (2019)
Introduction Symptoms of nicotine dependence among adolescents occur at an early stage in smoking onset and can be present even with low exposure to cigarettes. We aim to examine the early occurrence of symptoms of nicotine dependence and how they pr
Externí odkaz:
https://doaj.org/article/d85f4b4431a4414999cbfedee2d3d199
Autor:
Carmen Torres, Francesco Sanna, Rafael Torrubia, Daniel Sampedro-Viana, Ignasi Oliveras, Toni Cañete, Javier González-Maeso, Cristóbal Río-Álamos, Ignacio Morón, Alberto Fernández-Teruel, Ana Sánchez-González, Carles Tapias-Espinosa, Peter Driscoll, Osvaldo Giorgi, Maria Giuseppa Corda, Susana Aznar, Adolf Tobeña
Publikováno v:
Neuroscience & Biobehavioral Reviews. 131:597-617
The Roman High- (RHA) and Low-(RLA) avoidance rat lines/strains were generated through bidirectional selective breeding for rapid (RHA) vs. extremely poor (RLA) two-way active avoidance acquisition. Compared with RLAs and other rat strains/stocks, RH
Publikováno v:
Psychopharmacology
Rationale The combination of several risk factors (sex, a prior underlying psychiatric condition, or early drug initiation) could induce the emergence of negative affect during cocaine abstinence and increase the risk of developing addiction. However
Publikováno v:
Psychopharmacology
Psychopharmacology (Berl)
Psychopharmacology (Berl)
Rationale In classical conditioning, sign-tracking reflects behavior directed toward a conditioned stimulus (CS) in expectation of a reward (unconditioned stimulus, US); in contrast, goal-tracking describes behavior directed toward the location of de
Publikováno v:
J Neurosci
Although cocaine is powerfully rewarding, not all individuals are equally prone to abusing this drug. We postulate that these differences arise in part because some individuals exhibit stronger aversive responses to cocaine that protect them from coc
Publikováno v:
Journal of Behavioral Addictions. 2(1):1-9
Externí odkaz:
https://www.ceeol.com/search/article-detail?id=623584
Autor:
Guy B. Williams, Trevor W. Robbins, Chun Meng, Hisham Ziauddeen, Karen D. Ersche, Jan Stochl, Edward T. Bullmore
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Resting-state functional connectivity provides novel insight into variations in neural networks associated with addiction to stimulant drugs in individuals with and without a family history of addiction, and both with and without persona
Autor:
Mark G. LeSage, Andrew C. Harris, Zachary Haave, Jonathan C. Gewirtz, Yayi Swain, Peter Muelken, Annika Skansberg, Danielle Lanzdorf
Publikováno v:
Psychopharmacology (Berl)
Understanding factors contributing to individual differences in vulnerability to opioid addiction is essential for developing more effective preventions and treatments, yet few reliable behavioral predictors of subsequent opioid self-administration h
Autor:
Marco Leyton, Sylvana M. Côté, Frank Vitaro, Jean R. Séguin, Alain Dagher, Natalia Jaworska, Michel Boivin, Natalie Castellanos-Ryan, Sophie Parent, Chawki Benkelfat, Richard E. Tremblay, Robert O. Pihl, Maria Tippler, Sylvia M. L. Cox
Publikováno v:
Neuropsychopharmacology. 45:1498-1505
The neurobiological traits that confer risk for addictions remain poorly understood. However, dopaminergic function throughout the prefrontal cortex, limbic system, and upper brainstem has been implicated in behavioral features that influence addicti