Zobrazeno 1 - 10
of 1 190
pro vyhledávání: '"adaptive immune system"'
Autor:
Wilbert Bouwman, Wim Verhaegh, Arie van Doorn, Reinier Raymakers, Tom van der Poll, Anja van de Stolpe
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract For many diseases, including cancer, infections, and auto-immune diseases, the immune response is a major determinant of disease progression, response to therapy, and clinical outcome. Innate and adaptive immune responses are controlled by c
Externí odkaz:
https://doaj.org/article/cdc8b2faa3e84af2b9f24d39809dadac
Publikováno v:
Bioactive Materials, Vol 44, Iss , Pp 164-183 (2025)
Animal models have been extensively used as a gold standard in various biological research, including immunological studies. Despite high availability and ease of handling procedure, they inadequately represent complex interactions and unique cellula
Externí odkaz:
https://doaj.org/article/7babaaba80b949c1846b1a7063c513a1
Autor:
Wills, Christopher, author
Publikováno v:
Why Ecosystems Matter : Preserving the Key to Our Survival, 2024, ill.
Externí odkaz:
https://doi.org/10.1093/oso/9780192887573.003.0009
Publikováno v:
Journal of Biological Dynamics, Vol 18, Iss 1 (2024)
ABSTRACTThe adaptive immune system has two types of plasma cells (PC), long-lived plasma cells (LLPC) and short-lived plasma cells (SLPC), that differ in their lifespan. In this paper, we propose that LLPC is crucial to the clearance of viral particl
Externí odkaz:
https://doaj.org/article/7c46143c7e0740369c5afc646c5cd0c7
Publikováno v:
Neurobiology of Disease, Vol 202, Iss , Pp 106710- (2024)
Neurodegenerative diseases (NDs) are a type of common chronic progressive disorders characterized by progressive damage to specific cell populations in the nervous system, ultimately leading to disability or death. Effective treatments for these dise
Externí odkaz:
https://doaj.org/article/9fa20b027af84044b9f95821e64b72c4
Publikováno v:
Biomolecules, Vol 14, Iss 10, p 1249 (2024)
Bacterial Lysates are immunostimulants clinically prescribed for the prevention of respiratory tract infections (RTIs). It has been shown that Bacterial Lysates upregulate the immune system, acting both on innate and adaptive reactions. In fact, ther
Externí odkaz:
https://doaj.org/article/226ad988bb784f52a20ad115d95e20f9
Autor:
Michaela Hörner, Sandy Popp, Julien Branchu, Giovanni Stevanin, Frédéric Darios, Stephan Klebe, Janos Groh, Rudolf Martini
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
We have previously demonstrated that neuroinflammation by the adaptive immune system acts as a robust and targetable disease amplifier in a mouse model of Spastic Paraplegia, type 11 (SPG11), a complicated form of Hereditary Spastic Paraplegia (HSP).
Externí odkaz:
https://doaj.org/article/b3030858c55f4bb4871901a5455dc32c
Publikováno v:
Biomedical Journal, Vol 47, Iss 1, Pp 100637- (2024)
It has long been appreciated that cues from the innate immune system orchestrate downstream adaptive immune responses. Although previous work has focused on the roles of Toll-like receptors in this regard, relatively little is known about how Nod-lik
Externí odkaz:
https://doaj.org/article/a7d006034a1e456292fb5dc39c53310c
Autor:
Stefan Mimic, Başak Aru, Cemil Pehlivanoğlu, Hadi Sleiman, Pavle R. Andjus, Gülderen Yanıkkaya Demirel
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
This review aims to summarize the latest evidence about the role of innate and adaptive immunity in Amyotrophic Lateral Sclerosis (ALS). ALS is a devastating neurodegenerative disease affecting upper and lower motor neurons, which involves essential
Externí odkaz:
https://doaj.org/article/10499dd6006e4998a97953f2d545a09f
Publikováno v:
Neurobiology of Disease, Vol 187, Iss , Pp 106308- (2023)
Tissue-resident memory CD8 T cells are responsible for local immune surveillance in different tissues, including the brain. They constitute the first line of defense against pathogens and cancer cells and play a role in autoimmunity. A recently publi
Externí odkaz:
https://doaj.org/article/d2e156eb33404de8ba4e16826f5c3081