Zobrazeno 1 - 10
of 1 183
pro vyhledávání: '"adaptive immune system"'
Autor:
Wills, Christopher, author
Publikováno v:
Why Ecosystems Matter : Preserving the Key to Our Survival, 2024, ill.
Externí odkaz:
https://doi.org/10.1093/oso/9780192887573.003.0009
Publikováno v:
Journal of Biological Dynamics, Vol 18, Iss 1 (2024)
ABSTRACTThe adaptive immune system has two types of plasma cells (PC), long-lived plasma cells (LLPC) and short-lived plasma cells (SLPC), that differ in their lifespan. In this paper, we propose that LLPC is crucial to the clearance of viral particl
Externí odkaz:
https://doaj.org/article/7c46143c7e0740369c5afc646c5cd0c7
Autor:
Laura Hmiel, Suyu Zhang, Laventa M. Obare, Marcela Araujo de Oliveira Santana, Celestine N. Wanjalla, Boghuma K. Titanji, Corrilynn O. Hileman, Shashwatee Bagchi
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7266 (2024)
Atherosclerotic vascular disease disproportionately affects persons living with HIV (PLWH) compared to those without. The reasons for the excess risk include dysregulated immune response and inflammation related to HIV infection itself, comorbid cond
Externí odkaz:
https://doaj.org/article/c831234cb2234f2cb2b01c2c5e4777df
Autor:
Michaela Hörner, Sandy Popp, Julien Branchu, Giovanni Stevanin, Frédéric Darios, Stephan Klebe, Janos Groh, Rudolf Martini
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
We have previously demonstrated that neuroinflammation by the adaptive immune system acts as a robust and targetable disease amplifier in a mouse model of Spastic Paraplegia, type 11 (SPG11), a complicated form of Hereditary Spastic Paraplegia (HSP).
Externí odkaz:
https://doaj.org/article/b3030858c55f4bb4871901a5455dc32c
Publikováno v:
Biomedical Journal, Vol 47, Iss 1, Pp 100637- (2024)
It has long been appreciated that cues from the innate immune system orchestrate downstream adaptive immune responses. Although previous work has focused on the roles of Toll-like receptors in this regard, relatively little is known about how Nod-lik
Externí odkaz:
https://doaj.org/article/a7d006034a1e456292fb5dc39c53310c
Autor:
Stefan Mimic, Başak Aru, Cemil Pehlivanoğlu, Hadi Sleiman, Pavle R. Andjus, Gülderen Yanıkkaya Demirel
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
This review aims to summarize the latest evidence about the role of innate and adaptive immunity in Amyotrophic Lateral Sclerosis (ALS). ALS is a devastating neurodegenerative disease affecting upper and lower motor neurons, which involves essential
Externí odkaz:
https://doaj.org/article/10499dd6006e4998a97953f2d545a09f
Publikováno v:
Neurobiology of Disease, Vol 187, Iss , Pp 106308- (2023)
Tissue-resident memory CD8 T cells are responsible for local immune surveillance in different tissues, including the brain. They constitute the first line of defense against pathogens and cancer cells and play a role in autoimmunity. A recently publi
Externí odkaz:
https://doaj.org/article/d2e156eb33404de8ba4e16826f5c3081
Autor:
Daniel Sobral, Ana Filipa Fernandes, Miguel Bernardes, Patrícia Pinto, Helena Santos, João Lagoas-Gomes, José Tavares-Costa, José A. P. Silva, João Madruga Dias, Alexandra Bernardo, Jean-Charles Gaillard, Jean Armengaud, Vladimir Benes, Lúcia Domingues, Sara Maia, Jaime C. Branco, Ana Varela Coelho, Fernando M. Pimentel-Santos
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 382 (2024)
This study aims at identifying molecular biomarkers differentiating responders and non-responders to treatment with Tumor Necrosis Factor inhibitors (TNFi) among patients with axial spondyloarthritis (axSpA). Whole blood mRNA and plasma proteins were
Externí odkaz:
https://doaj.org/article/1ce5cc21929546879b104f7e022fd28b
Publikováno v:
Food Science and Human Wellness, Vol 11, Iss 5, Pp 1143-1155 (2022)
Green tea and its bioactive components possess many health-promoting and disease-preventing benefits, especially anti-inflammatory, antioxidant, anticancer, and metabolic modulation effects with multi-target modes of action. In contrast, the effects
Externí odkaz:
https://doaj.org/article/a245e1671b454d3e8fd7018716448603
Autor:
Alireza Faridar, Matthew Vasquez, Aaron D. Thome, Zheng Yin, Hui Xuan, Jing Hong Wang, Shixiang Wen, Xuping Li, Jason R. Thonhoff, Weihua Zhao, Hong Zhao, David R. Beers, Stephen T. C. Wong, Joseph C. Masdeu, Stanley H. Appel
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-13 (2022)
Abstract Background Regulatory T cells (Tregs) play a neuroprotective role by suppressing microglia and macrophage-mediated inflammation and modulating adaptive immune reactions. We previously documented that Treg immunomodulatory mechanisms are comp
Externí odkaz:
https://doaj.org/article/52b183fb078941b9b217ebdf26d36db7