Zobrazeno 1 - 10
of 129
pro vyhledávání: '"adaptive NK cells"'
Publikováno v:
Медицинская иммунология, Vol 26, Iss 5, Pp 891-896 (2024)
During infection with cytomegalovirus (HCMV), the content of so-called adaptive NK cells with the CD57+NKG2C+ phenotype increases in the peripheral blood, capable of exhibiting specialized functional activity aimed at controlling the infection upon r
Externí odkaz:
https://doaj.org/article/6e05e1788a984c39bb3b433c479837ba
Autor:
Mohammad Zahidul Hasan, Maren Claus, Nadine Krüger, Sarah Reusing, Eline Gall, Christina Bade-Döding, Armin Braun, Carsten Watzl, Markus Uhrberg, Lutz Walter
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
HLA-E expression plays a central role for modulation of NK cell function by interaction with inhibitory NKG2A and stimulatory NKG2C receptors on canonical and adaptive NK cells, respectively. Here, we demonstrate that infection of human primary lung
Externí odkaz:
https://doaj.org/article/922fdbe1e53a41a29cccf93946fdf801
Publikováno v:
Viruses, Vol 16, Iss 11, p 1746 (2024)
Natural killer (NK) cells are innate lymphocytes that can rapidly mount a response to their targets by employing diverse mechanisms. Due to their functional attributes, NK cells have been implicated in anti-viral and anti-tumour immune responses. Alt
Externí odkaz:
https://doaj.org/article/3c67c0214a664049b2661dcf9dae4d78
Autor:
David S.J. Allan, Chuanfeng Wu, Ryland D. Mortlock, Mala Chakraborty, Katayoun Rezvani, Jan K. Davidson-Moncada, Cynthia E. Dunbar, Richard W. Childs
Publikováno v:
Molecular Therapy: Oncolytics, Vol 28, Iss , Pp 74-87 (2023)
Multiple clinical trials exploring the potential of adoptive natural killer (NK) cell therapy for cancer have employed ex vivo expansion using feeder cells to obtain large numbers of NK cells. We have previously utilized the rhesus macaque model to c
Externí odkaz:
https://doaj.org/article/1edf27f82c9247a59d26f5b1e82ee10b
Autor:
Nerea Martín Almazán, Benedetta Maria Sala, Tatyana Sandalova, Yizhe Sun, Tom Resink, Frank Cichocki, Cecilia Söderberg-Nauclér, Jeffrey S. Miller, Adnane Achour, Dhifaf Sarhan
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionHuman cytomegalovirus (HCMV) reactivation causes complications in immunocompromised patients after hematopoietic stem cell transplantation (HSCT), significantly increasing morbidity and mortality. Adaptive Natural Killer (aNK) cells under
Externí odkaz:
https://doaj.org/article/f9173d9bcac94eeb99aeb099ec2e003d
Autor:
Norfarazieda Hassan, Suzy Eldershaw, Christine Stephens, Francesca Kinsella, Charles Craddock, Ram Malladi, Jianmin Zuo, Paul Moss
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionNK cells play an important role in suppression of viral replication and are critical for effective control of persistent infections such as herpesviruses. Cytomegalovirus infection is associated with expansion of ‘adaptive-memory’ NK
Externí odkaz:
https://doaj.org/article/2d68dfd5b4f545098ebad098abc774ac
Autor:
Mohammad Zahidul Hasan, Charlotte Höltermann, Beatrix Petersen, Annette Schrod, Kerstin Mätz-Rensing, Artur Kaul, Gabriela Salinas, Ralf Dressel, Lutz Walter
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Previous research on adaptive NK cells in rhesus macaques suffered from the lack of specific antibodies to differentiate between inhibitory CD94/NKG2A and stimulatory CD94/NKG2C heterodimeric receptors. Recently we reported an expansion of NKG2C rece
Externí odkaz:
https://doaj.org/article/799ddc125d754f04ac8d7044b091aab2
Autor:
Sarita Rani Jaiswal, Jaganath Arunachalam, Ashraf Saifullah, Rohit Lakhchaura, Dhanir Tailor, Anupama Mehta, Gitali Bhagawati, Hemamalini Aiyer, Bakulesh Khamar, Sanjay V. Malhotra, Suparno Chakrabarti
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The kinetics of NKG2C+ adaptive natural killer (ANK) cells and NKG2A+inhibitory NK (iNK) cells with respect to the incidence of SARS-CoV-2 infection were studied for 6 months in a cohort of healthcare workers following the administration of the heat-
Externí odkaz:
https://doaj.org/article/d87b5e5b06364190ae7b4af8f61af174
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Natural killer (NK) cells are an important component of the innate immune system due to their strong ability to kill virally infected or transformed cells without prior exposure to the antigen (Ag). However, the biology of human NK (hNK) cells has la
Externí odkaz:
https://doaj.org/article/4d5774e4ac8d45a3be0cccea4b8151ea
Autor:
Sarita Rani Jaiswal, Jaganath Arunachalam, Ashutosh Bhardwaj, Ashraf Saifullah, Rohit Lakhchaura, Mayank Soni, Gitali Bhagawati, Suparno Chakrabarti
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 1, Pp n/a-n/a (2022)
Abstract Objective SARS‐CoV‐2 infection results in severe lung disease in up to 50% of hospitalised patients. The aetiopathogenesis in a subset of such patients, who continue to have progressive pulmonary disease following virus clearance, remain
Externí odkaz:
https://doaj.org/article/9bdbeaa104384913a301abe783a83b48