Zobrazeno 1 - 10
of 1 916
pro vyhledávání: '"acylcarnitine"'
Autor:
Xin-Xin Huang, Lei Li, Run-Hao Jiang, Jian-Bing Yu, Yu-Qin Sun, Jinjun Shan, Jin Yang, Juan Ji, Shu-Qi Cheng, Yin-Feng Dong, Xi-Yue Zhang, Hai-Bin Shi, Sheng Liu, Xiu-Lan Sun
Publikováno v:
Journal of Advanced Research, Vol 61, Iss , Pp 133-149 (2024)
Introduction: Lipid metabolism dysfunction is widely involved in the pathological process of acute ischemic stroke (AIS). The coordination of lipid metabolism between neurons and astrocytes is of great significance. However, the full scope of lipid d
Externí odkaz:
https://doaj.org/article/ec252b19cefb4da9b51f5917b71cfed5
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Accumulation of acylcarnitines is a characteristic feature of various metabolic disorders affecting fatty acid metabolism. Despite extensive research, no specific molecules have been identified to induce ferroptosis through the regulation of acylcarn
Externí odkaz:
https://doaj.org/article/de047ea01eae4b10bf4c1d430a734c8f
Autor:
Yang Yang, Huaifeng Li, Ke Liu, Lu Zou, Shanshan Xiang, Yajun Geng, Xuechuan Li, Shimei Qiu, Jiahua Yang, Xuya Cui, Lin li, Yang Li, Weijian Li, Siyuan Yan, Liguo Liu, Xiangsong Wu, Fatao Liu, Wenguang Wu, Shili Chen, Yingbin Liu
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background The progression of gallbladder cancer (GBC) is accompanied by abnormal fatty acid β-oxidation (FAO) metabolism. Different types of lipids perform various biological functions. This study aimed to determine the role of acyl carnit
Externí odkaz:
https://doaj.org/article/5b660c93e1be43f0a020764fc026a2d8
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 41, Iss , Pp 101151- (2024)
Recurrent rhabdomyolysis, marked by skeletal muscle breakdown, can stem from various causes, including genetic disorders. We detail a patient of a 22-year-old male with carnitine palmitoyltransferase II (CPT-2) deficiency manifesting recurrent rhabdo
Externí odkaz:
https://doaj.org/article/93a83ab7b04e4c368ec87a964dbfed8d
Autor:
Emmanuel K. Ofori, Wormenor Dziedzorm, Alfred Buabeng, Francis K. Dogodzi, Laurinda X. Adusu‐Donkor, Segla K. Bernard, Seth K. Amponsah, Henry Asare‐Anane
Publikováno v:
Endocrinology, Diabetes & Metabolism, Vol 7, Iss 4, Pp n/a-n/a (2024)
ABSTRACT Introduction Data suggest malfunctioning mitochondria reduce oxidation and adenosine triphosphate (ATP) production, disrupting insulin signalling. Cytochrome c (CC), acylcarnitine (AC) and citrate synthase (CS) are essential components of th
Externí odkaz:
https://doaj.org/article/ca8beeb9e91849a08b48f511bde4e350
Autor:
Tian-Feng An, Zhi-Peng Zhang, Jun-Tang Xue, Wei-Ming Luo, Yang Li, Zhong-Ze Fang, Guo-Wei Zong
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
ObjectiveThe co-occurrence of kidney disease in patients with type 2 diabetes (T2D) is a major public health challenge. Although early detection and intervention can prevent or slow down the progression, the commonly used estimated glomerular filtrat
Externí odkaz:
https://doaj.org/article/ce2e6493d88f4f379c73ecf818c488f2
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 1, Pp 140-148 (2024)
Acylcarnitines are metabolic intermediates of fatty acids and branched-chain amino acids having vital biofunctions and pathophysiological significances. Here, we developed a high-throughput method for quantifying hundreds of acylcarnitines in one run
Externí odkaz:
https://doaj.org/article/b5eb61c924034af09deca7da2dec5471
Autor:
Shuhei Kidoguchi, Kunio Torii, Toshiharu Okada, Tomoko Yamano, Nanami Iwamura, Kyoko Miyagi, Tadashi Toyama, Masayuki Iwano, Ryoichi Miyazaki, Yosuke Shigematsu, Hideki Kimura
Publikováno v:
Diagnostics, Vol 14, Iss 20, p 2295 (2024)
Background/Objectives: Lipid metabolism and adiponectin modulate erythropoiesis in vitro and in general population studies and may also affect responsiveness to erythropoietin in patients undergoing haemodialysis (HD). However, little is known about
Externí odkaz:
https://doaj.org/article/2d6c36929f8b4025a6f3c418841eaf23
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1158 (2024)
The carnitine/acylcarnitine carrier (CAC) is a crucial protein for cellular energy metabolism, facilitating the exchange of acylcarnitines and free carnitine across the mitochondrial membrane, thereby enabling fatty acid β-oxidation and oxidative ph
Externí odkaz:
https://doaj.org/article/4c376f4cc0514df4be8c686e7ccc5f33
Autor:
Takafumi Nakajima, Taira Fukuda, Ikuko Shibasaki, Syotaro Obi, Masashi Sakuma, Shichiro Abe, Hirotsugu Fukuda, Shigeru Toyoda, Toshiaki Nakajima
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 51, Iss , Pp 101386- (2024)
Introduction: L-carnitine exerts protective effects, such as maintaining mitochondrial functions and decreasing reactive oxygen species, while acylcarnitine (AC) is linked to the development of heart failure and atherosclerosis. Hypothesis: Serum car
Externí odkaz:
https://doaj.org/article/0c3484da88a842cb926afd9ae2772f4d