Zobrazeno 1 - 10
of 274
pro vyhledávání: '"acyl azide"'
Publikováno v:
Molecules, Vol 27, Iss 5, p 1696 (2022)
In this study, we describe the synthesis of cyclic N-acyl amidines from readily available N-heteroarenes. The synthetic methodology utilized the versatile N-silyl enamine intermediates from the hydrosilylation of N-heteroarenes for the [3 + 2] cycloa
Externí odkaz:
https://doaj.org/article/f3165f8c2ef343128f81ba347737c2f8
Publikováno v:
Organic Letters. 23:7571-7574
An atom-economic N-to-C-directed solid-phase peptide synthesis is reported that uses benzyl (Bn) or (benzhydryl-carbamoyl)-methyl (BcM) esters of amino acids as the building blocks, which facilitate efficient hydrazinolysis, convenient conversion to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35789fb9c09e6d56c59ecf7bef31b0db
https://doi.org/10.1021/acs.orglett.1c02769
https://doi.org/10.1021/acs.orglett.1c02769
Publikováno v:
ACS Sustainable Chemistry & Engineering. 9:8679-8685
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9a4f0f7e9d9da8ee18206e627567c22
https://doi.org/10.1021/acssuschemeng.1c01786
https://doi.org/10.1021/acssuschemeng.1c01786
Publikováno v:
Organic Letters. 23:974-978
A palladium-catalyzed three-component carbonylative reaction for the synthesis of 3H-1,2,4-triazol-3-ones from hydrazonoyl chlorides and NaN3 has been achieved. The reaction presumably proceeds through a cascade carbonylation, acyl azide formation, C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59904e67742b03d69acbb5ea0d78e819
https://doi.org/10.1021/acs.orglett.0c04167
https://doi.org/10.1021/acs.orglett.0c04167
Autor:
Heba A Elhady, Hossa F. Al-Shareef
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 20:1929-1941
Background and Objective: Due to the well-documented anti-proliferative activity of 2-thiohydantoin incorporated with pyrazole, oxadiazole, quinazoline, urea, β-naphthyl carbamate and Schiff bases, they are noteworthy in pharmaceutical chemistry. Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d04ec2d12ef0785e6fbdf1415c6f4d
https://doi.org/10.2174/1389557520666200611093510
https://doi.org/10.2174/1389557520666200611093510
Publikováno v:
Chemistry – A European Journal. 26:13378-13382
The first divergent synthesis of both γ-amino acid and γ-lactam derivatives from meso-glutaric anhydrides is described. The organocatalytic desymmetrisation with TMSN3 relies on controlled generation of a nucleophilic ammonium azide species mediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f0723d31e44bd66380f1f8b9fe222b0
https://doi.org/10.1002/chem.202003280
https://doi.org/10.1002/chem.202003280
Publikováno v:
European Journal of Organic Chemistry. 2020:3847-3855
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84b01e0f23142f2252f2a80619cc4d8f
https://doi.org/10.1002/ejoc.202000494
https://doi.org/10.1002/ejoc.202000494
Publikováno v:
Organic Process Research & Development. 24:2342-2346
Diisocyanates used in polyurethanes are commonly prepared by phosgenation of petroleum-sourced diamines. This involves highly toxic phosgene and produces corrosive HCl, limiting synthetic applicati...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f830ce33423cda63f5469c001168cb0
https://doi.org/10.1021/acs.oprd.0c00167
https://doi.org/10.1021/acs.oprd.0c00167
Autor:
Sangil Han, Saegun Kim, Sang Hoon Han, Neeraj Kumar Mishra, Na Yeon Kwon, DongEun Kim, In Su Kim, Prithwish Ghosh
Publikováno v:
The Journal of Organic Chemistry. 85:2476-2485
A transition-metal-free deoxygenative C-H amination reaction of azine-N-oxides with acyl azides is described. The initial formation of an isocyanate from the starting acyl azide via a Curtius rearrangement can trigger a [3 + 2] dipolar cycloaddition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::417affaf7d271dfdd4d8566a58c5d79a
https://doi.org/10.1021/acs.joc.9b03173
https://doi.org/10.1021/acs.joc.9b03173
Publikováno v:
Reaction Chemistry & Engineering. 5:645-650
The development of new protocols for peptide bond formation which avoid side reactions, including epimerization, are very important. The acyl azide method for the preparation of peptides is very good at maintaining chiral integrity, however; acyl azi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2788da8e9e0fe294f3145a736233df23
https://doi.org/10.1039/d0re00034e
https://doi.org/10.1039/d0re00034e