Zobrazeno 1 - 10
of 1 425
pro vyhledávání: '"acute megakaryoblastic leukemia"'
Autor:
Carina Maria Pinto, Camila Marques Bertolucci, Alef Rafael Severino, Juliana Fernanda dos Santos Tosi, Maura R V Ikoma-Colturato
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 46, Iss 4, Pp 542-548 (2024)
Acute megakaryoblastic leukemia is characterized by heterogeneous biology and clinical behavior. Immunophenotypic characteristics include the expression of megakaryocytic differentiation markers (e.g. CD41, CD42a, CD42b, CD61) associated with immatur
Externí odkaz:
https://doaj.org/article/8390c2d59c3447a6a9cfe75afdf758cd
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
This case report describes a 2-month-old girl with acute megakaryoblastic leukemia (AMKL) harboring the t(1;22)(p13;q13) translocation, resulting in the RBM15::MRTFA fusion gene. She presented with massive hepatosplenomegaly and liver fibrosis and ac
Externí odkaz:
https://doaj.org/article/6717e1a833324ca987a961e9098df4d3
Autor:
N. K. Guskova, O. N. Selyutina, I. B. Lysenko, Yu. Yu. Kozel, O. V. Kozyuk, V. V. Dmitrieva, M. A. Baranenkova, A. S. Nozdricheva
Publikováno v:
Онкогематология, Vol 18, Iss 1, Pp 31-38 (2023)
We present a description of the difficulties in diagnosing acute megakaryoblastic leukemia in a child with Down syndrome aggravated by multiple comorbidities. In this case, a comprehensive assessment of clinical data, the results of an automatic comp
Externí odkaz:
https://doaj.org/article/70b5856df3b546e9977e6ba9a8bb3cbe
Akademický článek
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Autor:
Jixia Li, Maggie L. Kalev‐Zylinska
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Acute megakaryoblastic leukemia (AMKL) is a rare subtype of acute myeloid leukemia (AML) in which leukemic blasts have megakaryocytic features. AMKL makes up 4%–15% of newly diagnosed pediatric AML, typically affecting young children (less than 2 y
Externí odkaz:
https://doaj.org/article/88994926e86548418db4349b2b0a13b6
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionIt was first reported that germ cell tumor patients suffer from hematologic malignancies 37 years ago. Since then, the number of relevant reports has increased each year, with most cases being mediastinal germ cell tumor. Theories have be
Externí odkaz:
https://doaj.org/article/511f7541b8cf454aaae719cd583a9afb
Autor:
Junbin Huang, Guanhua Hu, Pan Suo, Lu Bai, Yifei Cheng, Yu Wang, XiaoHui Zhang, KaiYan Liu, YuQian Sun, LanPing Xu, Jun Kong, ChenHua Yan, Xiaojun Huang
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundAMKL without DS is a rare but aggressive hematological malignant disease in children, and it is associated with inferior outcomes. Several researchers have regarded pediatric AMKL without DS as high-risk or at least intermediate-risk AML an
Externí odkaz:
https://doaj.org/article/c9ccd54fdc7f41d6807e88d272330523
Akademický článek
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Autor:
Narun Su, Zifeng Li, Jiapeng Yang, Yang Fu, Xiaohua Zhu, Hui Miao, Yi Yu, Wenjin Jiang, Jun Le, Xiaowen Qian, Hongsheng Wang, Maoxiang Qian, Xiaowen Zhai
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Pediatric acute megakaryoblastic leukemia (AMKL) is a subtype of acute myeloid leukemia (AML) characterized by abnormal megakaryoblasts, and it is divided into the AMKL patients with Down syndrome (DS-AMKL) and AMKL patients without DS (non-DS-AMKL).
Externí odkaz:
https://doaj.org/article/c0cbe2dfe156468ab3f5d6745c377c67
Autor:
Jixia Li, Maggie L. Kalev-Zylinska
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Myeloid leukemia associated with Down syndrome (ML-DS) has a unique molecular landscape that differs from other subtypes of acute myeloid leukemia. ML-DS is often preceded by a myeloproliferative neoplastic condition called transient abnormal myelopo
Externí odkaz:
https://doaj.org/article/66352ea91848443b8e9ad3c4b7674b31