Zobrazeno 1 - 10
of 236
pro vyhledávání: '"acute HIV-1 infection"'
Autor:
Matrona Akiso, Daniel Muema, Robert Langat, Kewreshini K. Naidoo, Geoffrey Oino, Gaudensia Mutua, Christina Thobakgale, Daniel Ochiel, Kundai Chinyenze, Omu Anzala, Marianne W. Mureithi
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 4 (2024)
ABSTRACTPhenotypic changes and functional impairment of natural killer (NK) cells occur early in HIV-1 infection. Antiretroviral therapy (ART) effectively restores CD4+ T cell counts and suppresses HIV-1 to undetectable levels. The role and efficacy
Externí odkaz:
https://doaj.org/article/f52239c635764d56b3f92749b49d7601
Autor:
Zhen Li, Ping Yan, Rui Wang, Xiaofan Lu, Yang Zhang, Bin Su, Xin Zhang, Lin Yuan, Zhiying Liu, Wei Jiang, Tong Zhang, Hao Wu, Xiaojie Huang
Publikováno v:
Heliyon, Vol 9, Iss 5, Pp e15590- (2023)
HIV-1 infection causes T cell dysfunction that cannot be fully restored by anti-retroviral therapy (ART). Myeloid-derived suppressor cells (MDSCs) expand and suppress T cell function during viral infection. In this study, we evaluated the dynamics of
Externí odkaz:
https://doaj.org/article/c8e7f8d4d9a348ef856f4eed6cad4d37
Autor:
Keith Dunn, Rachel Rogers, Richard Bruce Simonson, Donghan Luo, Shubin Sheng, Purnima T. Kassam, Sareh Seyedkazemi, Hélène Hardy
Publikováno v:
HIV Research & Clinical Practice, Vol 22, Iss 2, Pp 55-61 (2021)
Background: Treatment during acute or early human immunodeficiency virus (HIV)-1 infection is associated with immunologic and virologic benefits. Objective: To evaluate darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) efficacy/saf
Externí odkaz:
https://doaj.org/article/04000d73446f4fdd8103c85c2ad64480
Autor:
Xiaofan Lu, Xin Zhang, Allen Ka Loon Cheung, Christiane Moog, Huan Xia, Zhen Li, Rui Wang, Yunxia Ji, Wei Xia, Zhiying Liu, Lin Yuan, Xiuwen Wang, Hao Wu, Tong Zhang, Bin Su
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Interactions between T follicular helper (Tfh) cells and germinal center B cells are essential for the differentiation of B cells and specific antibody responses against HIV-1 infection. However, the extent to which HIV-1 infection affects the dynami
Externí odkaz:
https://doaj.org/article/14cc6b7c4d3844039696444e035afcc2
Autor:
Michelle Chintanaphol, Carlo Sacdalan, Suteeraporn Pinyakorn, Rungsun Rerknimitr, Wiriyaporn Ridtitid, Piyapan Prueksapanich, Irini Sereti, Alexandra Schuetz, Trevor A. Crowell, Donn J. Colby, Merlin L. Robb, Nittaya Phanuphak, Jintanat Ananworanich, Serena S. Spudich, Eugène Kroon
Publikováno v:
Journal of Virus Eradication, Vol 6, Iss 1, Pp 7-10 (2020)
Background: The gut-associated lymphoid tissue (GALT) is a major reservoir of HIV-1 established early in acute HIV-1 infection (AHI). Sampling tissue from GALT can provide information about viral reservoirs and immune responses but may be complicated
Externí odkaz:
https://doaj.org/article/0be560181a7c4dadb36ba58022d4460b
Autor:
Lifeng Liu, Qiuyue Zhang, Peng Chen, Na Guo, Aixin Song, Xiaojie Huang, Wei Xia, Li Li, Christiane Moog, Hao Wu, Bin Su, Tong Zhang
Publikováno v:
BMC Immunology, Vol 20, Iss 1, Pp 1-8 (2019)
Abstract Background Helios has been reported to stabilize regulatory T (Treg) suppressive function. Programmed cell death protein 1 (PD-1) expression in three human monocyte subsets modulates immune responses. Recently, our team reported that three m
Externí odkaz:
https://doaj.org/article/4b2c6b80cabe41698f23dce9f1c4f5bd
Autor:
Muntsa Rocafort, Marc Noguera-Julian, Javier Rivera, Lucía Pastor, Yolanda Guillén, Jost Langhorst, Mariona Parera, Inacio Mandomando, Jorge Carrillo, Víctor Urrea, Cristina Rodríguez, Maria Casadellà, Maria Luz Calle, Bonaventura Clotet, Julià Blanco, Denise Naniche, Roger Paredes
Publikováno v:
Microbiome, Vol 7, Iss 1, Pp 1-17 (2019)
Abstract Background In rhesus macaques, simian immunodeficiency virus infection is followed by expansion of enteric viruses but has a limited impact on the gut bacteriome. To understand the longitudinal effects of HIV-1 infection on the human gut mic
Externí odkaz:
https://doaj.org/article/1debcf571709414390d7f376cd2d97f9
Akademický článek
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Autor:
Robert Badura, Russell B. Foxall, Dario Ligeiro, Miguel Rocha, Ana Godinho-Santos, Amelia C. Trombetta, Ana E. Sousa
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
HIV-1 infection induces B cell defects, not fully recovered upon antiretroviral therapy (ART). Acute infection and the early start of ART provide unique settings to address the impact of HIV on the B cell compartment. We took advantage of a cohort of
Externí odkaz:
https://doaj.org/article/e33b56418b2541d4bd25af07a0eeb3ef
Autor:
Guilherme B. Farias, Robert Badura, Carolina M. Conceição, André M. C. Gomes, Ana Godinho-Santos, Joel Laia, Pedro Rosmaninho, Diana F. Santos, Catarina Mota, Afonso R. M. Almeida, Susana M. Fernandes, Amelia C. Trombetta, Ana E. Sousa
Publikováno v:
Viruses, Vol 13, Iss 9, p 1805 (2021)
Monocytes are key modulators in acute viral infections, determining both inflammation and development of specific B- and T-cell responses. Recently, these cells were shown to be associated to different SARS-CoV-2 infection outcome. However, their rol
Externí odkaz:
https://doaj.org/article/4e88276be39245f1933a3d70f04c21f4