Zobrazeno 1 - 10
of 89
pro vyhledávání: '"activator protein 1 (AP-1)"'
Publikováno v:
The Ukrainian Biochemical Journal, Vol 91, Iss 1, Pp 80-85 (2019)
Chronic systemic inflammatory response syndrome (SIRS) underlies many diseases (sepsis, atherosclerosis, diabetes mellitus). According to research data of recent years the key role in the development of SIRS is played by the activation of various nuc
Externí odkaz:
https://doaj.org/article/388be3d28dc446d89240cbfc7f20699a
Autor:
Jin Hyung Kim, Seung-Taek Lee
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7521 (2022)
Polyamine levels decrease with menopause; however, little is known about the mechanisms regulated by menopause. In this study, we found that among the genes involved in the polyamine pathway, polyamine oxidase (PAOX) mRNA levels were the most signifi
Externí odkaz:
https://doaj.org/article/ee441e3f67cf4f84a09adc13c7147332
Publikováno v:
Virology Journal, Vol 15, Iss 1, Pp 1-14 (2018)
Abstract Background The pattern recognition receptors (PPRs) are the earliest phase of the host defense against pathogens in genital epithelium, and toll-like receptors (TLRs) are best characterized PPRs mediating innate immune responses. Herpes simp
Externí odkaz:
https://doaj.org/article/c87d84f2f02249eeae5e688e91606310
Autor:
Ling Cao, Yulin Liu, Dan Wang, Lan Huang, Feng Li, Jinbo Liu, Chaoqi Zhang, Zhibo Shen, Qun Gao, Weitang Yuan, Yi Zhang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-14 (2018)
Abstract Background Recent studies have reported that microRNAs (miRNAs) often function as negative post-transcriptional regulators with altered expression levels found in colorectal cancer (CRC). There have been few studies on miRNAs that regulate t
Externí odkaz:
https://doaj.org/article/a39af9bd9bb94ac3a8c1381a75d8c1fb
Akademický článek
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Autor:
Fengjuan Fan, Klaus Podar
Publikováno v:
Cancers, Vol 13, Iss 2326, p 2326 (2021)
Cancers
Cancers
Simple Summary As convergence points of signaling cascades, transcription factors (TFs) play a crucial role in cell physiology, including B cell differentiation, and are deregulated in solid and hematologic malignancies, including multiple myeloma (M
Akademický článek
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Autor:
Feixiang Yuan, Jiali Deng, Feifan Guo, Kai Li, Shanghai Chen, Qiwei Zhai, Weiping Jia, Yu Li, Zhimin Hu, Yuzhong Xiao, Qichen Fang, Hao Ying, Xiao Han, Lijian Hui, Yajie Guo, Fei Xiao, Yan Chen, Yuncai Zhou
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 20, Iss, Pp 138-148 (2019)
Molecular Metabolism, Vol 20, Iss, Pp 138-148 (2019)
Objective c-Jun, a prominent member of the activator protein 1 (AP-1) family, is involved in various physiology processes such as cell death and survival. However, a role of hepatic c-Jun in the whole-body metabolism is poorly understood. Methods We
Transcriptional Regulation of Thrombin-Induced Endothelial VEGF Induction and Proangiogenic Response
Autor:
Michèle Simon, Rusan Catar, Daniel Zickler, Hongfan Zhao, Guido Moll, Dashan Wu, Isa Hosp, Lei Chen, Janusz Witowski, Christian Luecht, Julian Kamhieh-Milz, Katarzyna Korybalska
Publikováno v:
Cells
Volume 10
Issue 4
Cells, Vol 10, Iss 910, p 910 (2021)
Volume 10
Issue 4
Cells, Vol 10, Iss 910, p 910 (2021)
Thrombin, the ligand of the protease-activated receptor 1 (PAR1), is a well-known stimulator of proangiogenic responses in vascular endothelial cells (ECs), which are mediated through the induction of vascular endothelial growth factor (VEGF). Howeve
Publikováno v:
Cells, Vol 10, Iss 461, p 461 (2021)
Cells
Cells
Epigenetic regulation and modification govern the transcriptional mechanisms that promote disease initiation and progression, but can also control the oncogenic processes, cell signaling networks, immunogenicity, and immune cells involved in anti-inf