Zobrazeno 1 - 10
of 1 402
pro vyhledávání: '"activated microglia"'
Autor:
Maheedhar Kodali, Leelavathi N. Madhu, Venkata Sai Vashishta Kolla, Sahithi Attaluri, Charles Huard, Yogish Somayaji, Bing Shuai, Chase Jordan, Xiaolan Rao, Sanath Shetty, Ashok K. Shetty
Publikováno v:
Military Medical Research, Vol 11, Iss 1, Pp 1-23 (2024)
Abstract Background Chronic Gulf War Illness (GWI) is characterized by cognitive and mood impairments, as well as persistent neuroinflammation and oxidative stress. This study aimed to investigate the efficacy of Epidiolex®, a Food and Drug Administ
Externí odkaz:
https://doaj.org/article/bdbff770ddb04c3cb3105d2ca65a4300
Autor:
Gunel Ayyubova, Maheedhar Kodali, Raghavendra Upadhya, Leelavathi N. Madhu, Sahithi Attaluri, Yogish Somayaji, Bing Shuai, Shama Rao, Goutham Shankar, Ashok K. Shetty
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-26 (2023)
Abstract Extracellular vesicles (EVs) released by human induced pluripotent stem cell-derived neural stem cells (hiPSC-NSCs) are enriched with miRNAs and proteins capable of mediating robust antiinflammatory activity. The lack of tumorigenic and immu
Externí odkaz:
https://doaj.org/article/babb73ba873d43e5aaae3a4f6631489f
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 1130 (2024)
Neuron damage by microglia, which act as macrophage cells in the brain, can result in various brain diseases. However, the function of pro-inflammatory or anti-inflammatory microglia in the neurons remains controversial. Guanylate-binding protein-2 (
Externí odkaz:
https://doaj.org/article/b931d973b6bb4baa86fc6361cf048c98
Autor:
Ian A. Clark, Bryce Vissel
Publikováno v:
Pharmacology Research & Perspectives, Vol 11, Iss 5, Pp n/a-n/a (2023)
Abstract Over a decade's experience of post‐stroke rehabilitation by administering the specific anti‐TNF biological, etanercept, by the novel perispinal route, is consistent with a wide range of chronically diminished neurological function having
Externí odkaz:
https://doaj.org/article/763eeb788d654238b279b83006fefdff
Akademický článek
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Akademický článek
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Publikováno v:
Neural Regeneration Research, Vol 17, Iss 3, Pp 503-507 (2022)
The expanded lifespan of people, while a positive advance, has also amplified the prevalence of age-related disorders, which include mild cognitive impairment, dementia, and Alzheimer’s disease. Therefore, competent therapies that could improve the
Externí odkaz:
https://doaj.org/article/840c5f97ce834c64ba0d1e33b827cc31
Autor:
Danica Nheu, Olivia Ellen, Sining Ye, Ezgi Ozturk, Maurice Pagnin, Stephen Kertadjaja, Paschalis Theotokis, Nikolaos Grigoriadis, Catriona McLean, Steven Petratos
Publikováno v:
Cells, Vol 11, Iss 23, p 3768 (2022)
Current therapeutics targeting chronic phases of multiple sclerosis (MS) are considerably limited in reversing the neural damage resulting from repeated inflammation and demyelination insults in the multi-focal lesions. This inflammation is propagate
Externí odkaz:
https://doaj.org/article/30b62862613640308024773349a1d419
Autor:
M.S. Bobola, L. Chen, C.K. Ezeokeke, T.A. Olmstead, C. Nguyen, A. Sahota, R.G. Williams, P.D. Mourad
Publikováno v:
Brain Stimulation, Vol 13, Iss 4, Pp 1014-1023 (2020)
Objective: Iaccarino et al. (2016) [1] exposed 1 h of light flickering at 40 Hz to awake 5XFAD Alzheimer’s Disease (AD) mouse models, generating action potentials at 40 Hz, activating ∼54% of microglia to colocalize with Aβ plaque, acutely, and
Externí odkaz:
https://doaj.org/article/1fd1baffce2948e3b367c13892425aaf
Akademický článek
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