Zobrazeno 1 - 10
of 186
pro vyhledávání: '"activated b-cell"'
Akademický článek
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Autor:
Krisna Murti, Hendrik Fender, Carolin Glatzle, Rhoda Wismer, Salvador Sampere-Birlanga, Vanessa Wild, Khalid Muhammad, Andreas Rosenwald, Edgar Serfling, Andris Avots
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
In Burkitt lymphoma (BL), a tumor of germinal center B cells, the pro-apoptotic properties of MYC are controlled by tonic B cell receptor (BCR) signals. Since BL cells do not exhibit constitutive NF-κB activity, we hypothesized that anti-apoptotic N
Externí odkaz:
https://doaj.org/article/3d77d058f7ce4d71a5391a7892166115
Autor:
Shishi Qi, Changwan Wang, Rui Zhang, Junyan Zhu, Xianteng Hou, Yingbo Jiang, Jiaxin Li, Miao Ren, Muwang Li, Fajian Hou
Publikováno v:
Journal of Innate Immunity, Pp 1-14 (2022)
Stimulator of interferon genes (STING) plays a pivotal role in type I interferon-mediated innate immune response to the cytoplasmic detection of aberrant DNA. STING is a membrane protein localized in endoplasmic reticulum (ER), which upon stimulation
Externí odkaz:
https://doaj.org/article/f439bbf22def413b8b0c042afd9bbc17
Publikováno v:
Journal of Family Medicine and Primary Care, Vol 11, Iss 8, Pp 4151-4158 (2022)
The most common non-Hodgkin lymphoma (NHL) subtype is diffuse large B-cell lymphoma (DLBCL). It accounts for roughly 30% of all cases of NHL affecting both nodal and extra nodal sites. There are molecular subtypes of DLBCL, germinal centre subtype (G
Externí odkaz:
https://doaj.org/article/6e3b0a3a799f4d51b24acf65334cb6b5
Publikováno v:
Human Pathology Reports, Vol 30, Iss , Pp 300682- (2022)
Signet ring cell lymphoma is an exceedingly rare subtype of non-Hodgkin lymphoma that was originally thought to be a morphologic variant of follicular lymphoma. To date, 56 cases have been reported, with the majority occurring in lymph nodes and bone
Externí odkaz:
https://doaj.org/article/2aa8a58af26440ee819ec9c8961a84ba
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Clinical Case Reports, Vol 9, Iss 2, Pp 669-672 (2021)
Abstract Although primary pancreatic lymphoma is a rare cause of pancreatic mass, this diagnosis should be considered during work‐up. Furthermore, when adequate diagnostic material is available from biopsy, complete workup of the lymphoma, includin
Externí odkaz:
https://doaj.org/article/236ea1d4027c40039578cd938e5ff1ee
Publikováno v:
Avicenna Journal of Medicine, Vol 10, Iss 04, Pp 241-248 (2020)
Background: CD10, BCL6, and MUM1 are commonly used immunohistochemical stains for classifying diffuse large B-cell lymphoma (DLBCL), which is useful in predicting outcome. Conflicting reports of the prognostic value of other markers such as BCL2, CD2
Externí odkaz:
https://doaj.org/article/21e69264957a45539c6717acbbe9b2d7
Autor:
Bibesh Pokhrel, Amit Thapa
Publikováno v:
Nepal Journal of Neuroscience, Vol 17, Iss 2, Pp 65-68 (2020)
Acute onset of diplopia with proptosis in case of primary CNS lymphoma has not been reported yet in the literature. Blurred vision, reduced vision, and floaters are the commonest reported presentations. We report a case of a 41-year-old HIV positive
Externí odkaz:
https://doaj.org/article/5b51384125e9449e971b0fcd9674b794
Autor:
Su Yao, Tairan Guo, Fen Zhang, Yu Chen, Fangping Xu, Donglan Luo, Xinlan Luo, Danyi Lin, Wendan Chen, Zhi Li, Yanhui Liu
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundF-box and WD repeat domain-containing 7 (Fbw7) is well known as a tumor suppressor and ubiquitin ligase which targets a variety of oncogenic proteins for proteolysis. We previously reported that Fbw7 promotes apoptosis in diffuse large B-ce
Externí odkaz:
https://doaj.org/article/9af55478f4b9424c97b9659a65a0b3d4