Zobrazeno 1 - 10
of 117
pro vyhledávání: '"actionable mutation"'
Autor:
Weifeng Liu, Huanqing Cheng, Zhen Huang, Yaping Li, Yanrui Zhang, Yongkun Yang, Tao Jin, Yang Sun, Zhiping Deng, Qing Zhang, Feng Lou, Shanbo Cao, Huina Wang, Xiaohui Niu
Publikováno v:
Molecular Oncology, Vol 18, Iss 4, Pp 939-955 (2024)
Osteosarcoma (OS) is a rare but aggressive malignancy. Despite previous reports, molecular characterization of this disease is not well understood, and little is known regarding OS in Chinese patients. Herein, we analyzed the genomic signatures of 73
Externí odkaz:
https://doaj.org/article/d6622d98e65f48fbb51c386ec5b7b510
Autor:
Sandra Zazo, Sandra Pérez‐Buira, Nerea Carvajal, Jenifer Plaza‐Sánchez, Rebeca Manso, Nuria Pérez‐González, Carolina Dominguez, Iván Prieto‐Potin, Jaime Rubio, Manuel Dómine, Virginia Lozano, Patricia Mohedano, David Carcedo, Rafael Carias, Federico Rojo
Publikováno v:
Cancer Medicine, Vol 13, Iss 3, Pp n/a-n/a (2024)
Abstract Objective This study aimed to describe the performance of a next‐generation sequencing (NGS) panel for the detection of precise genomic alterations in cancer in Spanish clinical practice. The impact of tumor characteristics was evaluated o
Externí odkaz:
https://doaj.org/article/f005a061fa8f46aca3f748bc4be3e83f
Autor:
Paola Ghanem, Maria Fatteh, David Olayinka Kamson, Archana Balan, Michael Chang, Jessica Tao, Jaishri Blakeley, The Johns Hopkins Molecular Tumor Board Investigators, Jenna Canzoniero, Stuart A. Grossman, Kristen Marrone, Karisa C. Schreck, Valsamo Anagnostou, Christine Pratilas, Taxiarchis Botsis, Rena Xian, Chris Gocke, Tseh Ming-Lin, Eitan Halper-Stromberg, Ying Zou, Kent Hardart, Jonathan Spiker, Kory Kreimeyer, Ting He, Katie Fiallos, Dana Petry, Kala Visvanathan, Antonio Wolff, Cesar Santa-Maria, Raquel Nunez, Christian Meyer, John Laterra, Vered Stearns, Karen Smith, Deborah Armstrong, Rachel Karchin, Katerina Karaindrou, Lily Zandi, Marta Majcherska, Faith Too, Monique Makell, Jennifer Lehman, Timsy Wanchoo, Jaime Wehr, Michael Conroy, Selina Shiqing Teh.
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundDespite the putatively targetable genomic landscape of high-grade gliomas, the long-term survival benefit of genomically-tailored targeted therapies remains discouraging.MethodsUsing glioblastoma (GBM) as a representative example of high-gr
Externí odkaz:
https://doaj.org/article/5bcfd0838b504f0dae83f9e83188528c
Publikováno v:
Journal of Molecular Pathology, Vol 4, Iss 1, Pp 31-43 (2023)
Lung cancer is one of the most common cancers and a leading cause of cancer-related mortality in Malaysia. This analysis aimed to evaluate the prevalence of actionable and common mutations, as well as co-mutations frequently occurring with EGFR varia
Externí odkaz:
https://doaj.org/article/f0d2746ca22e4b5185a60402f8f01d92
Autor:
Vasu Munjapara, Thatcher Heumann, Karisa C. Schreck, John M. Gross, Carlos Perez-Heydrich, Sachin K. Gujar, Charles G. Eberhart, Matthias Holdhoff
Publikováno v:
Case Reports in Oncology, Vol 15, Iss 3, Pp 909-917 (2022)
Recent advancements in understanding the biology of glioblastomas (GBM) and increasing adoption of genomic sequencing in oncology practice have led to the discovery of several targetable mutations in these cancers. Among them, the BRAF V600E mutation
Externí odkaz:
https://doaj.org/article/7eddc55ec4d04216b09735775ac98ab4
Autor:
Zhen Yang, Wei Cui, Ruoying Yu, Xinhua Dong, Jian Zhao, Lu Dai, Qiuxiang Ou, Hua Bao, Xue Wu, Chuanxin Wu, Jinhuo Lai
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
PurposeCarcinoma of unknown primary (CUP) is a clinically aggressive disorder with early tumor dissemination. Identifying molecular traits of CUP can be not only beneficial for a better therapeutic approach but also potentially valuable for patients
Externí odkaz:
https://doaj.org/article/1b62c317f017400c97cb93da4e9a90ff
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Harsh N. Dongre, Hilde Haave, Siren Fromreide, Fredrik A. Erland, Svein Erik Emblem Moe, Sophia Manueldas Dhayalan, Rasmus Kopperud Riis, Dipak Sapkota, Daniela Elena Costea, Hans Jorgen Aarstad, Olav K. Vintermyr
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundTargeted next-generation sequencing (NGS) is increasingly applied in clinical oncology to advance personalized treatment. Despite success in many other tumour types, use of targeted NGS panels for assisting diagnosis and treatment of head a
Externí odkaz:
https://doaj.org/article/311eea7de5314fe2b6e8a52984fa80e3