Zobrazeno 1 - 10
of 32 063
pro vyhledávání: '"action-potential"'
Autor:
Magdalena Koszewicz, Jakub Ubysz, Edyta Dziadkowiak, Malgorzata Wieczorek, Slawomir Budrewicz
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-8 (2024)
Abstract Background The motor neuron survival protein performs numerous cellular functions; hence, spinal muscular atrophy (SMA) is considered to be a multi-organ disease with possible sensory system damage. The controversy surrounding the presence o
Externí odkaz:
https://doaj.org/article/7f1cd8e871fe4d2bbb5fd67c990ed98e
Autor:
Jason E. Pope, Ajay Antony, Erika A. Petersen, Steven M. Rosen, Dawood Sayed, Corey W. Hunter, Johnathan H. Goree, Chau M. Vu, Harjot S. Bhandal, Philip M. Shumsky, Todd A. Bromberg, G. Lawson Smith, Christopher M. Lam, Hemant Kalia, Jennifer M. Lee, Abeer Khurram, Ian Gould, Dean M. Karantonis, Timothy R. Deer
Publikováno v:
Pain and Therapy, Vol 13, Iss 5, Pp 1173-1185 (2024)
Abstract Introduction Drawbacks of fixed-output spinal cord stimulation (SCS) screening trials may lead to compromised trial outcomes and poor predictability of long-term success. Evoked compound action potential (ECAP) dose-controlled closed-loop (C
Externí odkaz:
https://doaj.org/article/b195b5f383db45dbaafd3d6e3bd10fda
Autor:
Harold Nijhuis, Jan-Willem Kallewaard, Johan van de Minkelis, Willem-Jan Hofsté, Lars Elzinga, Philippa Armstrong, Ismaïl Gültuna, Emre Almac, Ganesan Baranidharan, Serge Nikolic, Ashish Gulve, Jan Vesper, Birte E. Dietz, Dave Mugan, Frank J. P. M. Huygen
Publikováno v:
Pain and Therapy, Vol 13, Iss 5, Pp 1119-1136 (2024)
Abstract Introduction Closed-loop spinal cord stimulation (CL-SCS) is a recently introduced system that records evoked compound action potentials (ECAPs) from the spinal cord elicited by each stimulation pulse and uses this information to automatical
Externí odkaz:
https://doaj.org/article/93af0142dde4432b82140525a803b9d5
Autor:
Danny V. Lam, Justin Chin, Meagan K. Brucker-Hahn, Megan Settell, Ben Romanauski, Nishant Verma, Aniruddha Upadhye, Ashlesha Deshmukh, Aaron Skubal, Yuichiro Nishiyama, Jian Hao, J. Luis Lujan, Simeng Zhang, Bruce Knudsen, Stephan Blanz, Scott F. Lempka, Kip A. Ludwig, Andrew J. Shoffstall, Hyun-Joo Park, Erika Ross Ellison, Mingming Zhang, Igor Lavrov
Publikováno v:
Bioelectronic Medicine, Vol 10, Iss 1, Pp 1-16 (2024)
Abstract Background Spinal cord stimulation (SCS) has demonstrated multiple benefits in treating chronic pain and other clinical disorders related to sensorimotor dysfunctions. However, the underlying mechanisms are still not fully understood, includ
Externí odkaz:
https://doaj.org/article/b5b48affe6404089aa5540dfcae13e93
Autor:
Qiang Wen, Rui Zhang, Kejun Ye, Jun Yang, Hangchuan Shi, Zhu Liu, Yangpeng Li, Ting Liu, Shiyu Zhang, Wanpei Chen, Jingjing Wu, Weichao Liu, Xiaoqiu Tan, Ming Lei, Christopher L.-H. Huang, Xianhong Ou
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract We explored physiological effects of the sodium-glucose co-transporter-2 inhibitor empagliflozin on intact experimentally hypertrophic murine hearts following transverse aortic constriction (TAC). Postoperative drug (2–6 weeks) challenge r
Externí odkaz:
https://doaj.org/article/7a7224d6282a486ca9a2c8a589c4d075
Autor:
Faris Basalamah, Ismail Hadisoebroto Dilogo, Sunu Budhi Raharjo, Muchtaruddin Mansyur, Nuryati Chairani Siregar, Nurhadi Ibrahim, Budi Yuli Setianto, Yoga Yuniadi
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background Mesenchymal stem cells (MSCs) are known as one of the best candidate cells to produce cardiac pacemaker-like cells (CPLCs). Upregulation of TBX3 transcription factor and inhibition of the nodal signal pathway have a significant ro
Externí odkaz:
https://doaj.org/article/758f66040ed6433484c248243e32a3f3
Autor:
Balázs Horváth, Zsigmond Kovács, Csaba Dienes, Zalán Barta, József Óvári, Norbert Szentandrássy, János Magyar, Tamás Bányász, Péter P. Nánási
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Current density, the membrane current value divided by membrane capacitance (Cm), is widely used in cellular electrophysiology. Comparing current densities obtained in different cell populations assume that Cm and ion current magnitudes are
Externí odkaz:
https://doaj.org/article/8371437791444a409019823d2d96291b
Publikováno v:
Biologics: Targets & Therapy, Vol Volume 18, Pp 115-127 (2024)
Yafei Zhou,1,2 Rui Zhou,1,2 Wenjun Huang,1,2 Jie Wang,1,2 Congshan Jiang,1,2 Anmao Li,1,2 Christopher LH Huang,3 Yanmin Zhang1,2,4 1Key Laboratory of Precision Medicine to Pediatric Diseases of Shaanxi Province, Affiliated Children’s Hospital of Xi
Externí odkaz:
https://doaj.org/article/6f58cfb12bce4dcb9e32e859753e5261
Publikováno v:
Annals of Indian Academy of Neurology, Vol 27, Iss 2, Pp 183-187 (2024)
Objective: Diabetic peripheral neuropathy (DPN), a complication of diabetes, is detected only in later stages. Medial plantar nerve (MPL) can identify earlier stages of neuropathy. We evaluated the correlation of MPL sensory nerve action potentials (
Externí odkaz:
https://doaj.org/article/22f06ce1d4094e38bee22449c4803a88