Výsledky vyhledávání - "acetylleucine"

Akademický článek

Identification of metabolites associated with preserved muscle volume after aneurysmal subarachnoid hemorrhage due to high protein supplementation and neuromuscular electrical stimulation

Autor: Aaron M. Gusdon, Jude P. J. Savarraj, Diana Feng, Adam Starkman, Guoyan Li, Uttam Bodanapally, William Zimmerman, Alice S. Ryan, Huimahn A. Choi, Neeraj Badjatia

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)

Abstract The INSPIRE randomized clinical trial demonstrated that a high protein diet (HPRO) combined with neuromuscular electrical stimulation (NMES) attenuates muscle atrophy and may improve outcomes after aneurysmal subarachnoid hemorrhage We sough

Externí odkaz: https://doaj.org/article/7639677510464a93873d22f07d2361cd

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Akademický článek

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Safety and Efficacy of Acetyl-DL-Leucine in Certain Types of Cerebellar Ataxia: The ALCAT Randomized Clinical Crossover Trial

Autor: Feil, Katharina, Adrion, Christine, Schöls, Ludger, Steiner, Katharina Marie, Stendel, Claudia, Timmann, Dagmar, Naumann, Ivonne, Mansmann, Ulrich, Strupp, Michael, Group, ALCAT Study, Boesch, Sylvia, Doss, Sarah, Giordano, Ilaria, Hengel, Holger, Jacobi, Heike, Klockgether, Thomas, Klopstock, Thomas, Nachbauer, Wolfgang

Publikováno v: JAMA network open 4(12), e2135841 (2021). doi:10.1001/jamanetworkopen.2021.35841

Importance: Cerebellar ataxia is a neurodegenerative disease impairing motor function characterized by ataxia of stance, gait, speech, and fine motor disturbances. Objective: To investigate the efficacy, safety, and tolerability of the modified essen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::523a823d3d9fde8a68fe3bc543988ad0
https://pub.dzne.de/record/163389

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Efficacy of acetylleucine in vertigo and dizziness: a systematic review of randomised controlled trials

Autor: Florian Naudet, Rémy Boussageon, Helene Vaillant Roussel, Nematollah Jaafari, Clara Blanchard, Denis Pouchain, Paul Vanderkam, Marie Christine Perault-Pochat

Publikováno v: European Journal of Clinical Pharmacology
European Journal of Clinical Pharmacology, Springer Verlag, 2019, 75 (5), pp.603-607. ⟨10.1007/s00228-018-02617-6⟩
European Journal of Clinical Pharmacology, 2019, 75 (5), pp.603-607. ⟨10.1007/s00228-018-02617-6⟩

International audience; PURPOSE:To assess the efficacy of acetylleucine to improve or stop an attack of vertigo and dizziness (vertigo/dizziness).METHODS:Systematic review by 2 independent reviewers. Consultation of the Medline, Cochrane and Clinical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db787d3c2fddbfc7f30c0d7e649c5b73
https://hal.uca.fr/hal-01978421

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Effects of vestibular training on motion sickness, nystagmus, and subjective vertical

Autor: Olivier Deguine, Gilles Clément, Mathieu Bourg, Anne Pavy-LeTraon

Publikováno v: HAL
Journal of Vestibular Research
Journal of Vestibular Research, IOS Press, 2007, 17 (5-6), pp.227-37

International audience; Pitch head-and-trunk movements during constant velocity rotation are a provocative vestibular stimulus that produces vertigo and nausea. When exposed to this stimulus repeatedly, motion sickness symptoms diminish as the subjec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93c9be4daa34305dd7c5fcdbc4565e4a
https://doi.org/10.3233/ves-2007-175-604

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Effects of acetyl-DL-leucine on cerebellar ataxia (ALCAT trial): study protocol for a multicenter, multinational, randomized, double-blind, placebo-controlled, crossover phase III trial

Publikováno v: BMC Neurology
BMC Neurology, 17, 7
BMC neurology 17(1), 7 (2017). doi:10.1186/s12883-016-0786-x
BMC Neurology, 17, 1, pp. 7

Cerebellar ataxia (CA) is a frequent and often disabling condition that impairs motor functioning and impacts on quality of life (QoL). No medication has yet been proven effective for the symptomatic or even causative treatment of hereditary or non-h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353436a27b7732aec3d7b06a70edd90b
https://pubmed.ncbi.nlm.nih.gov/28068987

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Effects of acetyl-DL-leucine in patients with cerebellar ataxia: a case series

Autor: Julian Teufel, Regina Feuerecker, Maximilian Habs, Bart P.C. van de Warrenburg, Katharina Feil, Carolin Muth, Thomas Klopstock, Michael Strupp

Publikováno v: Journal of neurology 260(10), 2556-2561 (2013). doi:10.1007/s00415-013-7016-x
Journal of Neurology, 260, 2556-61
Journal of Neurology, 260, 10, pp. 2556-61

Item does not contain fulltext No existing medication has yet been shown to convincingly improve cerebellar ataxia. Therefore, the identification of new drugs for its symptomatic treatment is desirable. The objective of this case series was to evalua

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d03a4db879dc3e686972ec4a19549dc
https://pub.dzne.de/record/137073

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Characterization of the conglomerate form of acetyl-dl-leucine by thermal analysis and solubility measurements

Autor: Jean-Marie Autret, Nicolas Estime, Béatrice Biscans, Richard Pena, Sébastien Teychené

Publikováno v: Journal of Crystal Growth.

Starting from a mixture of enantiomers in solution, crystallization can generate different types of crystals. In order to determine which type of crystal is obtained in the case of acetyl leucine, an active pharmaceutical ingredient (API), analytical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1a8f3249b432bc3f693a8bc87785f4e
https://oatao.univ-toulouse.fr/6022/

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Acetylleucine chloromethyl ketone, an inhibitor of acylpeptide hydrolase, induces apoptosis of U937 cells

Autor: Satoshi Toyoshima, Jun Toda, Hiroshi Hojo, Dan Kambayashi, Mitsune Yamaguchi, Takehiro Sano

Publikováno v: Biochemical and biophysical research communications. 263(1)

Acetylleucine chloromethyl ketone (ALCK), an inhibitor of acylpeptide hydrolase (ACPH), inhibited the growth of human monoblastic U937 cells in a dose- and time-dependent manner. Morphology of the ALCK-exposed cells showed typical apoptosis, judging

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dc9605f2d08fae6d29b18319c5e14cf
https://pubmed.ncbi.nlm.nih.gov/10486267

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