Zobrazeno 1 - 10
of 36
pro vyhledávání: '"acetyl-CoA carboxylase 2"'
Autor:
Cláudia Correia, Jonas Christoffersson, Sandra Tejedor, Saïd El-Haou, Meztli Matadamas-Guzman, Syam Nair, Pierre Dönnes, Gentian Musa, Mattias Rohman, Monika Sundqvist, Rebecca B. Riddle, Bramasta Nugraha, Ioritz Sorzabal Bellido, Markus Johansson, Qing-Dong Wang, Alejandro Hidalgo, Karin Jennbacken, Jane Synnergren, Daniela Später
Publikováno v:
Cells, Vol 13, Iss 16, p 1339 (2024)
Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) constitute an appealing tool for drug discovery, disease modeling, and cardiotoxicity screening. However, their physiological immaturity, resembling CMs in the late fetal stage, limits the
Externí odkaz:
https://doaj.org/article/d686b5dc9d3a47b580a621b738a93f64
Akademický článek
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Autor:
Philipp Stüve, Lucía Minarrieta, Hanna Erdmann, Catharina Arnold-Schrauf, Maxine Swallow, Melanie Guderian, Freyja Krull, Alexandra Hölscher, Peyman Ghorbani, Jochen Behrends, Wolf-Rainer Abraham, Christoph Hölscher, Tim D. Sparwasser, Luciana Berod
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Mycobacterium tuberculosis (Mtb), the causative agent of human tuberculosis, is able to efficiently manipulate the host immune system establishing chronic infection, yet the underlying mechanisms of immune evasion are not fully understood. Evidence s
Externí odkaz:
https://doaj.org/article/8f8f910f03db44969c21545058c3b1ac
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta pharmaceutica Sinica. B, vol 10, iss 1
Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 42-60 (2020)
Acta pharmaceutica Sinica. B, vol 10, iss 1
Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 42-60 (2020)
The hepatic endoplasmic reticulum (ER)-anchored cytochromes P450 (P450s) are mixed-function oxidases engaged in the biotransformation of physiologically relevant endobiotics as well as of myriad xenobiotics of therapeutic and environmental relevance.
Akademický článek
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Akademický článek
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Autor:
William Yuan, Marcia C. Haigis, Alison E. Ringel, Samantha J. Wong, Joao A. Paulo, Haejin Yoon, Mark A. Currie
Publikováno v:
The Journal of Biological Chemistry
Since the discovery of the prolyl hydroxylases domain (PHD) proteins and their canonical hypoxia-inducible factor (HIF) substrate two decades ago, a number of in vitro hydroxylation (IVH) assays for PHD activity have been developed to measure the PHD
Autor:
Jochen Behrends, Hanna Erdmann, Tim Sparwasser, Freyja Krull, Peyman Ghorbani, Lucía Minarrieta, Maxine Swallow, Christoph Hölscher, Melanie Guderian, Alexandra Hölscher, Luciana Berod, Catharina Arnold-Schrauf, Wolf-Rainer Abraham, Philipp Stüve
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Frontiers in immunology
Frontiers in Immunology
Frontiers in immunology
Frontiers in Immunology
Mycobacterium tuberculosis (Mtb), the causative agent of human tuberculosis, is able to efficiently manipulate the host immune system establishing chronic infection, yet the underlying mechanisms of immune evasion are not fully understood. Evidence s
Autor:
Paul A. Dawson, Courtney B. Ferrebee
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 5, Iss 2, Pp 129-134 (2015)
Acta Pharmaceutica Sinica B, Vol 5, Iss 2, Pp 129-134 (2015)
The classical functions of bile acids include acting as detergents to facilitate the digestion and absorption of nutrients in the gut. In addition, bile acids also act as signaling molecules to regulate glucose homeostasis, lipid metabolism and energ