Zobrazeno 1 - 10
of 1 203
pro vyhledávání: '"abcc1"'
Autor:
Muhlis Akman, Ciro Monteleone, Gabriella Doronzo, Martina Godel, Francesca Napoli, Alessandra Merlini, Virginia Campani, Valeria Nele, Elisa Balmas, Tatiana Chontorotzea, Simona Fontana, Sabrina Digiovanni, Francesca Alice Barbu, Elena Astanina, Niloufar Jafari, Iris Chiara Salaroglio, Joanna Kopecka, Giuseppe De Rosa, Thomas Mohr, Alessandro Bertero, Luisella Righi, Silvia Novello, Giorgio Vittorio Scagliotti, Federico Bussolino, Chiara Riganti
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-23 (2024)
Abstract Background In non-small cell lung cancer (NSCLC) the efficacy of chemo-immunotherapy is affected by the high expression of drug efflux transporters as ABCC1 and by the low expression of ABCA1, mediating the isopentenyl pyrophosphate (IPP)-de
Externí odkaz:
https://doaj.org/article/4a6851a8a8824044acb7cc89ddb408bf
Autor:
Jing Liu, Yijiang Bai, Yong Feng, Xianlin Liu, Bo Pang, Shuai Zhang, Mengzhu Jiang, Anhai Chen, Huping Huang, Yongjia Chen, Jie Ling, Lingyun Mei
Publikováno v:
Redox Biology, Vol 74, Iss , Pp 103218- (2024)
The ABCC1 gene belongs to the ATP-binding cassette membrane transporter superfamily, which plays a crucial role in the efflux of various endogenous and exogenous substances. Mutations in ABCC1 can result in autosomal dominant hearing loss. However, t
Externí odkaz:
https://doaj.org/article/3419b384213d4917ac5d872ffc55dffd
Autor:
Guoling Liang, Xiaosong Jiang, Kangxiang Qin, Yun Hu, Chenxi Che, Yuntao Li, Chunlin Wang, Changkao Mu, Huan Wang
Publikováno v:
Aquaculture Reports, Vol 36, Iss , Pp 102057- (2024)
Scylla paramamosain is an important mariculture animal. In the present study, we examined the physiological and biochemical characteristics of juvenile S. paramamosain under hypoosmotic stress and further verified the function of ABCC1, a key transpo
Externí odkaz:
https://doaj.org/article/3fb933dad3054577b3b35f0112a01742
Autor:
Tiantian Wang, Dean Rao, Chenan Fu, Yiming Luo, Junli Lu, Huifang Liang, Limin Xia, Wenjie Huang
Publikováno v:
Translational Oncology, Vol 41, Iss , Pp 101882- (2024)
ABCC1 belongs to the ATP-binding cassette (ABC) superfamily, which encompasses a total of 48 constituent members. ABCC1 has been shown to be associated with the growth, progression, and drug resistance of various types of cancer. However, the impact
Externí odkaz:
https://doaj.org/article/12d253cf070442739be867399eefc6ee
Publikováno v:
Journal of Pharmacy and Bioallied Sciences, Vol 15, Iss 1, Pp 15-20 (2023)
Background: The ATP-Binding Cassette (ABC) transporter has long been studied to confer drug resistance in human tumors and play important role in metabolic processes and cellular signaling. The overexpression of ABCB1, ABCC1, ABCC2, ABCC3, and ABCG2
Externí odkaz:
https://doaj.org/article/d53673fc0b574ca0a182f3139053b83a
Emerging Role of ABC Transporters in Glia Cells in Health and Diseases of the Central Nervous System
Publikováno v:
Cells, Vol 13, Iss 9, p 740 (2024)
ATP-binding cassette (ABC) transporters play a crucial role for the efflux of a wide range of substrates across different cellular membranes. In the central nervous system (CNS), ABC transporters have recently gathered significant attention due to th
Externí odkaz:
https://doaj.org/article/7f6835879d6e4847afa231bf59726ccd
Autor:
Sahel Vahdati, Alf Lamprecht
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 493 (2024)
Reversing the multiple drug resistance (MDR) arising from the overexpression of the efflux transporters often fails mainly due to the high toxicity or the poor water solubility of the inhibitors of these transporters. Here, we demonstrate the deliver
Externí odkaz:
https://doaj.org/article/5b0521a16dae4c5d964c43b3529c8aee
Akademický článek
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Autor:
Jelena Dinić, Ana Podolski-Renić, Miodrag Dragoj, Sofija Jovanović Stojanov, Ana Stepanović, Ema Lupšić, Milica Pajović, Mirna Jovanović, Dušica Petrović Rodić, Dragana Marić, Maja Ercegovac, Milica Pešić
Publikováno v:
Diagnostics, Vol 13, Iss 24, p 3617 (2023)
Lung cancer remains the leading cause of cancer death globally, with non-small cell lung cancer (NSCLC) accounting for the majority of cases. Multidrug resistance (MDR), often caused by ATP-binding cassette (ABC) transporters, represents a significan
Externí odkaz:
https://doaj.org/article/db08c6ecaea04e3b8de6101fc3e2f20a
Autor:
Christina Gobin, Samuel Inkabi, Chayil C. Lattimore, Tongjun Gu, James N. Menefee, Mayrangela Rodriguez, Heather Kates, Christopher Fields, Tengfei Bian, Natalie Silver, Chengguo Xing, Clayton Yates, Rolf Renne, Mingyi Xie, Kristianna M. Fredenburg
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundFor several decades, Black patients have carried a higher burden of laryngeal cancer among all races. Even when accounting for sociodemographics, a disparity remains. Differentially expressed microRNAs have been linked to racially disparate
Externí odkaz:
https://doaj.org/article/b049aa693b8c4476a8737d88677325b6