Zobrazeno 1 - 10
of 10 788
pro vyhledávání: '"abc-transporter"'
Publikováno v:
Zhongliu Fangzhi Yanjiu, Vol 51, Iss 7, Pp 594-599 (2024)
The ATP-binding cassette (ABC) transporter superfamily comprises membrane proteins that efflux various substrates across extra- and intracellular membranes. Among them, ABCB1, ABCG2, and ABCC1 are directly linked to tumor multidrug resistance (MDR).
Externí odkaz:
https://doaj.org/article/a8107902d04d428483c3790fea6cf0a1
Autor:
Arash Veshkini, Christa Kühn, Franziska Dengler, Lisa Bachmann, Wendy Liermann, Christiane Helm, Reiner Ulrich, Cora Delling, Harald M. Hammon
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
IntroductionCryptosporidium parvum (C. parvum) is the most prevalent enteric protozoan parasite causing infectious diarrhea in neonatal calves worldwide with a direct negative impact on their health and welfare. This study utilized next-generation se
Externí odkaz:
https://doaj.org/article/c2d7bfdef93b4b03804709b51f09cb2c
Publikováno v:
Channels, Vol 18, Iss 1 (2024)
KATP channels are ligand-gated potassium channels that couple cellular energetics with membrane potential to regulate cell activity. Each channel is an eight subunit complex comprising four central pore-forming Kir6 inward rectifier potassium channel
Externí odkaz:
https://doaj.org/article/ae5b90c7be9645178e9ac3531c0fa733
Autor:
Xin-Yan Lu, Hongxu Jin
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Resistance to chemotherapeutic agents poses a significant challenge in cancer treatment, particularly with doxorubicin, a widely used drug for various cancers, including breast cancer, leukaemia, osteosarcoma, and gastrointestinal cancers. This revie
Externí odkaz:
https://doaj.org/article/cdf6cd17a3964a198d1cabd5704a731e
Autor:
M. Melet, S. Blanchet, P. Barbarin, E. A. Maunders, S. L. Neville, V. Rong, L. Mereghetti, C. A. McDevitt, A. Hiron
Publikováno v:
mSphere, Vol 9, Iss 11 (2024)
ABSTRACT Zinc (Zn) is an essential cofactor for numerous bacterial proteins and altering Zn availability is an important component of host innate immunity. During infection, adaptation to both Zn deprivation and excess is critical for pathogenic bact
Externí odkaz:
https://doaj.org/article/9e0c7193687048349d8c4f1030bd975e
Autor:
Yuejia Chen, Du Guo, Xin Wang, Changbin Zhang, Yatian Chen, Qinghua Luo, Yujiao Chen, Lili Yang, Zhibo Zhang, Tian Hong, Zhengyu Zhang, Haohao Dong, Shenghai Chang, Jianping Hu, Xiaodi Tang
Publikováno v:
MedComm, Vol 5, Iss 11, Pp n/a-n/a (2024)
Abstract The filamentous temperature‐sensitive (Fts) protein FtsEX plays a pivotal role in Escherichia coli (E. coli) cell division by facilitating the activation of peptidoglycan hydrolysis through the adaptor EnvC. FtsEX belongs to the type VII A
Externí odkaz:
https://doaj.org/article/1217d081d0d04c89b4fa30fb5ecf0160
Autor:
Xiao Li, Zhen Zheng, Wanzhen Zhou, Huixian Huang, Yang Zhou, Qinyang Xu, Xiaolu Zhu, Yincheng Teng
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-14 (2024)
Abstract Ovarian cancer (OV) is a highly fatal malignant disease that commonly manifests at an advanced stage. Drug resistance, particularly platinum resistance, is a leading cause of treatment failure because first-line systemic chemotherapy primari
Externí odkaz:
https://doaj.org/article/f6ae17dbebe44a009c974bd8e56cdd36
Autor:
Manuel T. Anlauf, Florestan L. Bilsing, Jens Reiners, Olivia Spitz, Eymen Hachani, Sander H. J. Smits, Lutz Schmitt
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Type I secretion systems (T1SS) facilitate the secretion of substrates in one step across both membranes of Gram-negative bacteria. A prime example is the hemolysin T1SS which secretes the toxin HlyA. Secretion is energized by the ABC transp
Externí odkaz:
https://doaj.org/article/a0598cad15ab4e3883050d21aafba132
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-9 (2024)
Abstract Background The process of producing proteins in bacterial systems and secreting them through ATP-binding cassette (ABC) transporters is an area that has been actively researched and used due to its high protein production capacity and effici
Externí odkaz:
https://doaj.org/article/5d3664f096aa47c0b74dc1f990637a93
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