Zobrazeno 1 - 10
of 63
pro vyhledávání: '"aCSF, artificial cerebrospinal fluid"'
Akademický článek
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Publikováno v:
IBRO Neuroscience Reports
Long-term cannabis use during adolescence has deleterious effects in brain that are largely ascribed to the activation of cannabinoid-1 receptors (CB1Rs) by delta-9-tetrahydrocannabinol (∆9-THC), the primary psychoactive compound in marijuana. Syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b03004304b8098b3141dcd72323ca6f0
https://pubmed.ncbi.nlm.nih.gov/34667972
https://pubmed.ncbi.nlm.nih.gov/34667972
Autor:
Patricia Padilla-Cortés, Raquel Martínez-Méndez, Margarita Gómez-Chavarín, Tatiana Fiordelisio, Daniel Perez-Torres, Gabriel Gutiérrez-Ospina
Publikováno v:
IBRO Reports
IBRO Reports, Vol 7, Iss, Pp 108-116 (2019)
IBRO Reports, Vol 7, Iss, Pp 108-116 (2019)
Highlights • Birth-enucleation modifies the spontaneous activity of somatosensory brain areas. • Calcium spike amplitude increases in the thalamus of 1-day-old rats after enucleation. • Calcium spike amplitude decreases in the cortex of 1-day-o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39e8f23fd3c8b852452382e4e92ca3f9
https://doi.org/10.1016/j.ibror.2019.11.003
https://doi.org/10.1016/j.ibror.2019.11.003
Autor:
Zhenyi Li, Yali Wang, Sanya Ahmed, Martin Vreugdenhil, Yujiao Zhang, Jianbin Wen, Georgiana Neagu, Chunjie Liu
Publikováno v:
IBRO Reports
IBRO Reports, Vol 6, Iss, Pp 122-131 (2019)
IBRO Reports, Vol 6, Iss, Pp 122-131 (2019)
Highlights • CA3 gamma oscillation (γ) drives CA1 gamma and suppresses CA1 intrinsic fast γ. • μ-opioid receptor (MOR) activation reduces γ frequency in CA3 and CA1. • MOR activation in CA1 phase-uncouples CA1 γ from CA3 γ. • Uncoupling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8867c275a463eabf2fe3c82f772d7b
https://doi.org/10.1016/j.ibror.2019.01.004
https://doi.org/10.1016/j.ibror.2019.01.004
Publikováno v:
The Journal of Biological Chemistry
Familial British dementia and familial Danish dementia are neurodegenerative disorders caused by mutations in the gene integral membrane protein 2B (ITM2b) encoding BRI2, which tunes excitatory synaptic transmission at both presynaptic and postsynapt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e551c51b462662a8e05481a6c8b948
https://pubmed.ncbi.nlm.nih.gov/34416235
https://pubmed.ncbi.nlm.nih.gov/34416235
Autor:
Fiona Randall, Peter Atkinson, Fiona E. N. LeBeau, Christopheer M. Morris, Joshua Curry, Clare Tweedy, John-Paul Taylor, Gavin J. Clowry, Daniel Erskine, Amy K. Reeve, Nathan Kindred, Christopher M. Williams
Publikováno v:
Neurobiology of Disease, Vol 149, Iss, Pp 105226-(2021)
Neurobiology of Disease
Neurobiology of Disease
Abnormal excitability in cortical networks has been reported in patients and animal models of Alzheimer's disease (AD), and other neurodegenerative conditions. Whether hyperexcitability is a core feature of alpha(α)-synucleinopathies, including deme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e332102b731825f1f488e183205ac8d9
http://www.sciencedirect.com/science/article/pii/S0969996120305015
http://www.sciencedirect.com/science/article/pii/S0969996120305015
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
Xia Zhu, Xiaojing Meng, Qian Meng, Wenjie Zhou, Yan Jin, Yanhua Li, Wenjuan Tao, Zhi Zhang, An Liu, Yu Mao
Publikováno v:
The Journal of Biological Chemistry
Anxiety is often comorbid with pain. Delta opioid receptors (DORs) are promising targets for the treatment of pain and mental disorders with little addictive potential. However, their roles in anxiety symptoms at different stages of pain are unclear.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b46bc7f685c6b17b3a0ca5d5ab99b9be
https://pubmed.ncbi.nlm.nih.gov/33428940
https://pubmed.ncbi.nlm.nih.gov/33428940
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 22, Iss, Pp-(2020)
Molecular Genetics and Metabolism Reports
Molecular Genetics and Metabolism Reports
Mucopolysaccharidosis III A (MPS IIIA) is an autosomal recessive lysosomal storage disorder caused by deficiency of the enzyme sulfamidase. The disorder results in accumulation of heparan sulfate, lysosomal enlargement and cellular and organ dysfunct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5926859a8eba56927ab317fa4978ed
http://www.sciencedirect.com/science/article/pii/S221442691930196X
http://www.sciencedirect.com/science/article/pii/S221442691930196X
Autor:
Emma V. Bird, Veselin I. Andreev, Anne King, Claire R. Christmas, Fiona M. Boissonade, Ilona Obara, Tommaso Iannitti
Publikováno v:
Neuroscience
Highlights • We identified XCR1 in the peripheral and central nervous systems and demonstrated its upregulation following nerve injury. • In injured nerve, XCR1 is present in nerve fibers, CD45-positive leucocytes and Schwann cells. • In Vc, XC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02bcb4a7cea2f85b2d557bea86bf7c0e
https://doi.org/10.1016/j.neuroscience.2018.03.030
https://doi.org/10.1016/j.neuroscience.2018.03.030