Zobrazeno 1 - 10
of 82
pro vyhledávání: '"a1 astrocytes"'
Autor:
Helin Li, Ying Liu, Yucao Sun, Hangyu Guo, Shiyan Lv, Wenhui Guo, Jiyu Ren, Yufu Wang, Jianing Zu, Jinglong Yan, Nanxiang Wang
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Spinal cord injury (SCI) is a serious neurological injury that causes severe trauma to motor and sensory functions. Although long considered incurable, recent research has brought new hope for functional recovery from SCI. After SCI, astrocytes are a
Externí odkaz:
https://doaj.org/article/a4c9f69dc4774984b3c5d43245bb5fc3
Autor:
Bismark Gatica-Garcia, Michael J Bannon, Irma Alicia Martínez-Dávila, Luis O Soto-Rojas, David Reyes-Corona, Lourdes Escobedo, Minerva Maldonado-Berny, ME Gutierrez-Castillo, Armando J Espadas-Alvarez, Manuel A Fernandez-Parrilla, Juan U Mascotte-Cruz, CP Rodríguez-Oviedo, Irais E Valenzuela-Arzeta, Claudia Luna-Herrera, Francisco E Lopez-Salas, Jaime Santoyo-Salazar, Daniel Martinez-Fong
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 9, Pp 2057-2067 (2024)
[INLINE:1] Parkinsonism by unilateral, intranigral β-sitosterol β-D-glucoside administration in rats is distinguished in that the α-synuclein insult begins unilaterally but spreads bilaterally and increases in severity over time, thus replicating
Externí odkaz:
https://doaj.org/article/9b9457524ca44836abbf77cbfbe9fce8
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-28 (2023)
Abstract In the contexts of aging, injury, or neuroinflammation, activated microglia signaling with TNF-α, IL-1α, and C1q induces a neurotoxic astrocytic phenotype, classified as A1, A1-like, or neuroinflammatory reactive astrocytes. In contrast to
Externí odkaz:
https://doaj.org/article/e90a6d5dabcd4ca2bf15e2f68d526558
Autor:
Yinquan Fang, Xiao Ding, Yihe Zhang, Lei Cai, Yuan Ge, Kaiyang Ma, Rong Xu, Shanshan Li, Mengmeng Song, Hong Zhu, Jiaqi Liu, Jianhua Ding, Ming Lu, Gang Hu
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-20 (2022)
Abstract Background Fluoxetine, a selective serotonin reuptake inhibitor, has been reported to directly bind with 5-HT2B receptor (5-HT2BR), but the precise mechanisms, whereby fluoxetine confers the anti-depressive actions via 5-HT2BR is not fully u
Externí odkaz:
https://doaj.org/article/5d73d8b60f9348a3b5004699e3758449
Akademický článek
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Akademický článek
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Publikováno v:
Molecules, Vol 28, Iss 14, p 5363 (2023)
Highly neurotoxic A1-reactive astrocytes have been associated with several human neurodegenerative diseases. Complement protein C3 expression is strongly upregulated in A1 astrocytes, and this protein has been shown to be a specific biomarker of thes
Externí odkaz:
https://doaj.org/article/bdd2b3fb6c454afdbb6c5b5700076128
Autor:
He-Yang Zhang, Yan Wang, Youdi He, Ting Wang, Xiao-Hui Huang, Chang-Ming Zhao, Lei Zhang, Si-Wei Li, Changyong Wang, Yan-Nv Qu, Xiao-Xia Jiang
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-13 (2020)
Abstract Background Astrocytes are crucial regulators in the central nervous system. Abnormal activation of astrocytes contributes to some behavior deficits. However, mechanisms underlying the effects remain unclear. Here, we studied the activation o
Externí odkaz:
https://doaj.org/article/58aface283084b5699c0fd586dfa81a7
Autor:
Ting Li, Tongtong Liu, Xuhui Chen, Li Li, Miaomiao Feng, Yue Zhang, Li Wan, Chuanhan Zhang, Wenlong Yao
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-15 (2020)
Abstract Background Activated astrocytes play important roles in chronic post-surgical pain (CPSP). Recent studies have shown reactive astrocytes are classified into A1 and A2 phenotypes, but their precise roles in CPSP remain unknown. In this study,
Externí odkaz:
https://doaj.org/article/a5d6f0156cf743c39e0aa6148357be1c
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-13 (2019)
Abstract Chronic pain is a critical clinical problem with an increasing prevalence. However, there are limited effective prevention measures and treatments for chronic pain. Astrocytes are the most abundant glial cells in the central nervous system a
Externí odkaz:
https://doaj.org/article/9a9a04dd7e0e480faeadbc7173bfc6ef