Legume Lectins Inhibit Human Parainfluenza Virus Type 2 Infection by Interfering with the Entry

Autor: Myles O’Brien, Hiroshi Komada, Masato Tsurudome, Mitsuo Kawano, Hidetaka Yamamoto, Sahoko Kihira, Miho Tanemura, Yukari Ura, Sayaka Takano, Aoi Koyama, Jun Uematsu

Publikováno v: Viruses, Vol 4, Iss 7, Pp 1104-1115 (2012)

Three lectins with different sugar binding specificities were investigated for anti-viral activity against human parainfluenza virus type 2 (hPIV-2). The lectins, concanavalin A (Con A), lens culinaris agglutinin (LCA) and peanut agglutinin (PNA), in

Externí odkaz: https://doaj.org/article/4b7bbf5adbca472c89e65bd0740dff43

Inhibition of Human Parainfluenza Virus Type 2 Growth in Vitro by Catechin is caused by the Inhibition of Genome and mRNA Syntheses and by the Disruption of Cytoskeleton, and that by Tannic Acid is Mainly Caused by Genome Synthesis Inhibition and the Disruption of Cytoskeleton

Autor: Komada, Hiroshi, Uematsu, Jun, Kihira, Sahoko, Uchida, Mika, Sakakura, Yurika, Deguchi, Sayuri, Sakai, Kae, Yamamoto, Hidetaka, Kawano, Mitsuo, Tsurudome, Masato, O'Brien, Myles

The antiviral activities of catechin mixture (catechin) and tannic acid against human parainfluenza virus type 2 (hPIV-2) were investigated in vitro. Catechin and tannic acid both inhibited cell fusion induced by hPIV-2 in LLCMK2 cells. However, high

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a02e30631ea227a636d0c70a44b4024e

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Inhibitions of human parainfluenza virus type 2 replication by ribavirin and mycophenolate mofetil are restored by guanosine and S-(4-nitrobenzyl)-6-thioinosine.

Autor: Uematsu J; Microbiology and Immunology Section, Department of Clinical Nutrition, Graduate School of Health Science, Suzuka University of Medical Science, Suzuka, Mie, Japan., Sakai-Sugino K; Department of Clinical Nutrition, Faculty of Health Science, Suzuka University of Medical Science, Suzuka, Mie, Japan., Kihira-Nakanishi S; Department of Clinical Nutrition, Faculty of Health Science, Suzuka University of Medical Science, Suzuka, Mie, Japan., Yamamoto H; Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science, Suzuka, Mie, Japan., Hirai K; Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science, Suzuka, Mie, Japan., Kawano M; Department of Microbiology, Mie University Graduate School of Medicine, Tsu, Mie, Japan., Nishio M; Department of Microbiology, Mie University Graduate School of Medicine, Tsu, Mie, Japan., Tsurudome M; Department of Microbiology, Mie University Graduate School of Medicine, Tsu, Mie, Japan., O'Brien M; Graduate School of Mie Prefectural College of Nursing, Tsu, Mie, Japan., Komada H; Microbiology and Immunology Section, Department of Clinical Nutrition, Graduate School of Health Science, Suzuka University of Medical Science, Suzuka, Mie, Japan.

Publikováno v: Drug discoveries & therapeutics [Drug Discov Ther] 2019; Vol. 13 (6), pp. 314-321.