Zobrazeno 1 - 10
of 236
pro vyhledávání: '"a Ikuo Nakanishi"'
Autor:
Ryota Mori, Masami Abe, Yuma Saimoto, Saki Shinto, Sara Jodai, Manami Tomomatsu, Kaho Tazoe, Minato Ishida, Masataka Enoki, Nao Kato, Tomohiro Yamashita, Yuki Itabashi, Ikuo Nakanishi, Kei Ohkubo, Sachiko Kaidzu, Masaki Tanito, Yuta Matsuoka, Kazushi Morimoto, Ken-ichi Yamada
Publikováno v:
Redox Biology, Vol 73, Iss , Pp 103186- (2024)
Recent studies have highlighted the indispensable role of oxidized lipids in inflammatory responses, cell death, and disease pathogenesis. Consequently, inhibitors targeting oxidized lipids, particularly lipid-derived radicals critical in lipid perox
Externí odkaz:
https://doaj.org/article/7d182cc53e094558b215ae9e0f93a292
Autor:
Hiroko P. Indo, Moragot Chatatikun, Ikuo Nakanishi, Ken-ichiro Matsumoto, Motoki Imai, Fumitaka Kawakami, Makoto Kubo, Hiroshi Abe, Hiroshi Ichikawa, Yoshikazu Yonei, Hisashi J. Beppu, Yukiko Minamiyama, Takuro Kanekura, Takafumi Ichikawa, Atthaphong Phongphithakchai, Lunla Udomwech, Suriyan Sukati, Nurdina Charong, Voravuth Somsak, Jitbanjong Tangpong, Sachiyo Nomura, Hideyuki J. Majima
Publikováno v:
Biomolecules, Vol 14, Iss 10, p 1317 (2024)
The universe began 13.8 billion years ago, and Earth was born 4.6 billion years ago. Early traces of life were found as soon as 4.1 billion years ago; then, ~200,000 years ago, the human being was born. The evolution of life on earth was to become in
Externí odkaz:
https://doaj.org/article/bd42301e1c894abeaf22b55934bc3dad
Publikováno v:
Antioxidants, Vol 13, Iss 10, p 1165 (2024)
Planar catechin (PCat), a natural antioxidant with a fixed 3D catechin structure on a plane, exhibits radical-scavenging activity approximately five times stronger than the conventional catechin. We synthesized a compound, PCat-TrOH, by binding Trolo
Externí odkaz:
https://doaj.org/article/a4acb9e80e524b6483f72df6bd3ea9f2
Publikováno v:
Molecules, Vol 29, Iss 18, p 4467 (2024)
Catechin is one of the representative antioxidants that shows physiological activities such as an anti-cancer effect. We have developed a chemically modified catechin analog possessing a planar structure, which shows an enhanced radical-scavenging ac
Externí odkaz:
https://doaj.org/article/2cd6148ceec6438ca7c32f16d1c9f833
Autor:
Yoshimi Shoji, Yuri Terashima, Kei Ohkubo, Hiromu Ito, Kouichi Maruyama, Shunichi Fukuzumi, Ikuo Nakanishi
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4417 (2024)
2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide (PTIO•), a persistent nitronyl nitroxide radical, has been used for the detection and trapping of nitric oxide, as a redox mediator for batteries, for the activity estimation of antioxidants, a
Externí odkaz:
https://doaj.org/article/556f8b3dd1dc42b2a432feb4614e4357
Autor:
Megumi Ueno, Raj Kumar Parajuli, Hiromu Ito, Megumi Iiyama, Saaya Suzuki, Ken-ichiro Matsumoto, Ikuo Nakanishi, Ichio Aoki, Akira Sumiyoshi
Publikováno v:
Advances in Redox Research, Vol 8, Iss , Pp 100067- (2023)
The effects of X-ray irradiation on the redox status of colorectal tissues were investigated using magnetic resonance redox imaging.The pyrrolidine-ring nitroxyl contrast agent, 3-carbamoyl-2,2,5,5-tetramethylpyrrolidine-N-oxyl (CmP), was used as a s
Externí odkaz:
https://doaj.org/article/c91f96c187594713827e5ae9e7fcb325
Autor:
Daisuke Masuda, Ikuo Nakanishi, Kei Ohkubo, Hiromu Ito, Ken-ichiro Matsumoto, Hiroshi Ichikawa, Moragot Chatatikun, Wiyada Kwanhian Klangbud, Manas Kotepui, Motoki Imai, Fumitaka Kawakami, Makoto Kubo, Hirofumi Matsui, Jitbanjong Tangpong, Takafumi Ichikawa, Toshihiko Ozawa, Hsiu-Chuan Yen, Daret K. St Clair, Hiroko P. Indo, Hideyuki J. Majima
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 128 (2024)
Questions about which reactive oxygen species (ROS) or reactive nitrogen species (RNS) can escape from the mitochondria and activate signals must be addressed. In this study, two parameters, the calculated dipole moment (debye, D) and permeability co
Externí odkaz:
https://doaj.org/article/2f9fcb72f1c247bc85463ff752e569d2
Publikováno v:
Pharmaceutics, Vol 15, Iss 11, p 2536 (2023)
Radiotherapy, in which X-rays are commonly used, is one of the most effective procedures for treating cancer. However, some cancer cells become resistant to radiation therapy, leading to poor prognosis. Therefore, a new therapeutic method is required
Externí odkaz:
https://doaj.org/article/d42d358abf434dd09e4c0666365342fa
Publikováno v:
Molecules, Vol 28, Iss 13, p 5002 (2023)
A neutral, stable radical, 2,2-diphenyl-1-picrylhydrazyl radical (DPPH•), has been frequently used to estimate the activity of antioxidants for more than 60 years. However, the number of reports about the effect of metal ions on the reactivity of D
Externí odkaz:
https://doaj.org/article/bbaa4f59a72e448f8de1f089d0b53a0f
Autor:
Ikuo Nakanishi, Yoshimi Shoji
Publikováno v:
Electrochemistry Communications, Vol 134, Iss , Pp 107190- (2022)
2,2-Diphenyl-1-picrylhydrazyl radical (DPPH•) is a water-insoluble stable radical that has been used to evaluate the activity of antioxidants as a reactivity model of reactive oxygen species. In this work, the cyclic voltammetry of DPPH• solubili
Externí odkaz:
https://doaj.org/article/6bc1d96d780c4775a7fee38dea22fd63