Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Zymogen activity"'
Autor:
Stine Friis, Daniel Tadeo, Sylvain M. Le-Gall, Henrik Jessen Jürgensen, Katiuchia Uzzun Sales, Eric Camerer, Thomas H. Bugge
Publikováno v:
BMC Biology, Vol 15, Iss 1, Pp 1-17 (2017)
Abstract Background Matriptase is a membrane serine protease essential for epithelial development, homeostasis, and regeneration, as well as a central orchestrator of pathogenic pericellular signaling in the context of inflammatory and proliferative
Externí odkaz:
https://doaj.org/article/96b236299cf5401b81b37fb6c67c3c7b
Autor:
Lars Vitved, Evelina Stankevic, Jan K. Jensen, Annika W. Nonboe, Lotte K. Vogel, Ásdís K. Frost, Kristian W Goderum, Lasse Holt-Danborg, Signe Skovbjerg
Publikováno v:
Holt-Danborg, L, Skovbjerg, S, Goderum, K W, Nonboe, A W, Stankevic, E, Frost, Á K, Vitved, L, Jensen, J K & Vogel, L K 2020, ' Insights into the regulation of the matriptase-prostasin proteolytic system ', The Biochemical journal, vol. 477, no. 22, pp. 4349-4365 . https://doi.org/10.1042/BCJ20200630
The membrane-associated prostasin and matriptase belonging to the S1A subfamily of serine proteases, are critical for epithelial development and maintenance. The two proteases are involved in the activation of each other and are both regulated by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc9b8c827f7b28e660d41783f2da281d
https://pure.au.dk/portal/da/publications/insights-into-the-regulation-of-the-matriptaseprostasin-proteolytic-system(9ba711c0-6c63-42ce-ab5f-ef35d419d815).html
https://pure.au.dk/portal/da/publications/insights-into-the-regulation-of-the-matriptaseprostasin-proteolytic-system(9ba711c0-6c63-42ce-ab5f-ef35d419d815).html
Autor:
Lotte K. Vogel, Annika W. Nonboe, Cecilia C. Thomas, Lars Vitved, Ásdís K. Frost, Lasse Holt-Danborg, Signe Skovbjerg, Jan K. Jensen, Zebin Hong, Christine R. Schar
Publikováno v:
Skovbjerg, S, Holt-Danborg, L, Nonboe, A W, Hong, Z, Frost, Á K, Schar, C R, Thomas, C C, Vitved, L, Jensen, J K & Vogel, L K 2020, ' Inhibition of an active zymogen protease : the zymogen form of matriptase is regulated by HAI-1 and HAI-2 ', The Biochemical journal, vol. 477, no. 9, pp. 1779-1794 . https://doi.org/10.1042/BCJ20200182
The membrane-bound serine protease matriptase belongs to a rare subset of serine proteases that display significant activity in the zymogen form. Matriptase is critically involved in epithelial differentiation and homeostasis, and insufficient regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b62bac235b7508cd90b4bebc7689f5c
https://pure.au.dk/portal/da/publications/inhibition-of-an-active-zymogen-protease(c1e131da-975e-4df8-a670-6db09d2af227).html
https://pure.au.dk/portal/da/publications/inhibition-of-an-active-zymogen-protease(c1e131da-975e-4df8-a670-6db09d2af227).html
Autor:
Henrik J. Jürgensen, Sylvain M. Le-Gall, Stine Friis, Thomas H. Bugge, Daniel Tadeo, Katiuchia Uzzun Sales, Eric Camerer
Publikováno v:
BMC Biology
BMC Biology, BioMed Central, 2017, 15 (1), pp.46. ⟨10.1186/s12915-017-0384-4⟩
BMC Biology, BioMed Central, 2017, 15 (1), pp.46. 〈10.1186/s12915-017-0384-4〉
Friis, S, Tadeo, D, Le-Gall, S M, Jurgensen, H J, Sales, K U, Camerer, E & Bugge, T H 2017, ' Matriptase zymogen supports epithelial development, homeostasis and regeneration ', B M C Biology, vol. 15, 46 . https://doi.org/10.1186/s12915-017-0384-4
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
BMC Biology, Vol 15, Iss 1, Pp 1-17 (2017)
BMC Biology, BioMed Central, 2017, 15 (1), pp.46. ⟨10.1186/s12915-017-0384-4⟩
BMC Biology, BioMed Central, 2017, 15 (1), pp.46. 〈10.1186/s12915-017-0384-4〉
Friis, S, Tadeo, D, Le-Gall, S M, Jurgensen, H J, Sales, K U, Camerer, E & Bugge, T H 2017, ' Matriptase zymogen supports epithelial development, homeostasis and regeneration ', B M C Biology, vol. 15, 46 . https://doi.org/10.1186/s12915-017-0384-4
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
BMC Biology, Vol 15, Iss 1, Pp 1-17 (2017)
Matriptase is a membrane serine protease essential for epithelial development, homeostasis, and regeneration, as well as a central orchestrator of pathogenic pericellular signaling in the context of inflammatory and proliferative diseases. Matriptase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57cf5e8a34b6aad3034edf09ac0ea7fb
https://www.hal.inserm.fr/inserm-01532895
https://www.hal.inserm.fr/inserm-01532895
Akademický článek
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Akademický článek
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Autor:
Holt-Danborg L; Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3, DK-2200 Copenhagen N, Denmark., Skovbjerg S; Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3, DK-2200 Copenhagen N, Denmark., Goderum KW; Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3, DK-2200 Copenhagen N, Denmark., Nonboe AW; Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3, DK-2200 Copenhagen N, Denmark., Stankevic E; Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3, DK-2200 Copenhagen N, Denmark., Frost ÁK; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark., Vitved L; Department of Cancer and Inflammation, University of Southern Denmark, Odense, Denmark., Jensen JK; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark., Vogel LK; Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3, DK-2200 Copenhagen N, Denmark.
Publikováno v:
The Biochemical journal [Biochem J] 2020 Nov 27; Vol. 477 (22), pp. 4349-4365.
Autor:
Skovbjerg S; Department of Cellular and Molecular Medicine, The Panum Institute, University of Copenhagen, Denmark., Holt-Danborg L; Department of Cellular and Molecular Medicine, The Panum Institute, University of Copenhagen, Denmark., Nonboe AW; Department of Cellular and Molecular Medicine, The Panum Institute, University of Copenhagen, Denmark., Hong Z; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark., Frost ÁK; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark., Schar CR; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark., Thomas CC; Department of Cellular and Molecular Medicine, The Panum Institute, University of Copenhagen, Denmark., Vitved L; Department of Cancer and Inflammation, University of Southern Denmark, Odense, Denmark., Jensen JK; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark., Vogel LK; Department of Cellular and Molecular Medicine, The Panum Institute, University of Copenhagen, Denmark.
Publikováno v:
The Biochemical journal [Biochem J] 2020 May 15; Vol. 477 (9), pp. 1779-1794.