Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Zygmunt Cieśla"'
Autor:
Zygmunt Cieśla, Piotr A. Mieczkowski, Joanna Rytka, M. U. Fikus, Piotr Koprowski, Ewa Śledziewska-Gójska
Publikováno v:
Europe PubMed Central
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We reported previously that the product of the DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, belongs to a family of proteins that are involved in DNA repair and replication. The family includes S. cerevisiae proteins Rad2p and its huma
Publikováno v:
Journal of bacteriology. 180(6)
Replication of the Escherichia coli chromosome is performed by the DNA polymerase III holoenzyme (Pol III HE) (15, 16, 21). Pol III HE is an asymmetric, dimeric complex containing a total of 18 subunits (10 distinct), which are capable of coordinatel
Autor:
Zygmunt Cieśla, Piotr Jonczyk
Publikováno v:
Molecular and General Genetics MGG. 180:617-620
Exposure of Escherichia coli dnaA strains to UV light results in a transient resumption of chromosome replication at 42 degrees C, the temperature restrictive to these mutants. Capability of dnaA mutants to replicate DNA at 42 degrees C can be stabil
Autor:
Zygmunt Cieśla, Piotr Polaczek
Publikováno v:
Molecular and General Genetics MGG. 190:326-330
The replication pattern of the plasmid pBR322 was examined in the dnaA mutants of Escherichia coli. The rate of pBR322 DNA synthesis is markedly decreased after dnaA cells are shifted to the restrictive temperature of 42 degrees C. However, addition
Autor:
Zygmunt Cieśla
Publikováno v:
Molecular and General Genetics MGG. 186:298-300
A tif-1 umuC36 double mutant of Escherichia coli was constructed. It has been found that the umuC36 mutation prevents both increased spontaneous mutagenesis and enhanced reactivation of UV-irradiated lambda, phenomena normally observed in the tif-1 s
Autor:
Piotr Jonczyk, Zygmunt Cieśla
Publikováno v:
Moleculargeneral genetics : MGG. 171(1)
It has been found that UV irradiation of dnaA mutants of E. coli K-12 enables the initiation of DNA synthesis at a temperature restrictive to these mutants. The UV-induced DNA synthesis is dependent on protein synthesis and on a transcriptional event
Publikováno v:
Mutation research. 70(3)
L-Cystine and L-cysteine specifically reverse the mutagenic action of azide in Salmonella typhimurium and Escherichia coli. To establish whether the L-cysteine biosynthetic pathway is involved in azide-induced mutagenesis, several derivatives of a mu
Autor:
Zygmunt Cieśla, Piotr Polaczek
Publikováno v:
Moleculargeneral genetics : MGG. 194(1-2)
Thermal inactivation of the dnaA gene product leads to a considerable decrease in the rate of replication of ColE1-like plasmids. To test the possibility that the dnaA protein may affect synthesis of RNA I, which is an inhibitor of primer formation,
Autor:
Marcin Filutowicz, Zygmunt Cieśla
Publikováno v:
Mutation research. 66(3)
Publikováno v:
Mutation research. 62(2)
Azide-induced mutagenesis was investigated in Salmonella typhimurium and Escherichia coli . Azide was highly effective in inducing mutations in uvrB, uvrB recA and uvrB recB mutants of S. typhimurium . The mutagenic effect of azide was also observed