Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Zwi Berneman"'
Autor:
Stijn Verhulst, Sven Dekeyzer, Griet Nijs, Maxime De Laere, Marie-Madeleine Couttenye, Zwi Berneman, Nathalie Cools, Manon Huizing, Ella Roelant, Toon Van Genechten, Jolien Van den Bossche, Barbara Stein, kim De Rycke, Caroline Deschepper, Katja Hazes, Renke Peeters, Katrien Van De Walle, Sabine Maes, Stephanie Vanden Bossche, Kim Caluwaert, Joris Verlooy, Koen Norga, Sebastien Anguille, Eva Lion
Publikováno v:
BMJ Open, Vol 14, Iss 3 (2024)
Introduction Diffuse intrinsic pontine glioma (DIPG) and paediatric high-grade glioma (pHGG) are aggressive glial tumours, for which conventional treatment modalities fall short. Dendritic cell (DC)-based immunotherapy is being investigated as a prom
Externí odkaz:
https://doaj.org/article/448d729eeeb445d19d32a432ced49800
Autor:
Jolien Van den Bossche, Maxime De Laere, Koen Deschepper, Paul Germonpré, Yvan Valcke, Jan Lamont, Barbara Stein, Kirsten Van Camp, Charlotte Germonpré, Griet Nijs, Ella Roelant, Sébastien Anguille, Eva Lion, Zwi Berneman
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0307204 (2024)
Malignant pleural mesothelioma (MPM) is an aggressive cancer with a very poor prognosis. Recently, immune checkpoint inhibition (ICI) has taken center stage in the currently ongoing revolution that is changing standard-of-care treatment for several m
Externí odkaz:
https://doaj.org/article/0fc25e2cc8ca4f028c79ed96487bc0db
Autor:
Gizem Oner, Glenn Broeckx, Christophe Van Berckelaer, Karen Zwaenepoel, Sevilay Altintas, Zafer Canturk, Wiebren Tjalma, Zwi Berneman, Marc Peeters, Patrick Pauwels, Peter A. vanDam
Publikováno v:
Cancer Medicine, Vol 12, Iss 17, Pp 17901-17913 (2023)
Abstract Background Oestrogen receptor positive (ER+)/HER‐2 negative breast cancer (BC) is considered to be an immunologically cold tumour compared to triple negative breast cancer. Therefore, the tumour microenvironment (TME) of ER+/HER‐2 negati
Externí odkaz:
https://doaj.org/article/191b42cd16644c468f4e0ac985be28d8
Autor:
Angelina Konnova, Fien H. R. De Winter, Akshita Gupta, Lise Verbruggen, An Hotterbeekx, Matilda Berkell, Laure-Anne Teuwen, Greetje Vanhoutte, Bart Peeters, Silke Raats, Isolde Van der Massen, Sven De Keersmaecker, Yana Debie, Manon Huizing, Pieter Pannus, Kristof Y. Neven, Kevin K. Ariën, Geert A. Martens, Marc Van Den Bulcke, Ella Roelant, Isabelle Desombere, Sébastien Anguille, Zwi Berneman, Maria E. Goossens, Herman Goossens, Surbhi Malhotra-Kumar, Evelina Tacconelli, Timon Vandamme, Marc Peeters, Peter van Dam, Samir Kumar-Singh
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundPatients with cancer, especially hematological cancer, are at increased risk for breakthrough COVID-19 infection. So far, a predictive biomarker that can assess compromised vaccine-induced anti-SARS-CoV-2 immunity in cancer patients has not
Externí odkaz:
https://doaj.org/article/ad857598e2b741baaf1d0d02701cbefe
Autor:
Inge Vangenechten, Petr Smejkal, Jiri Zavrelova, Ondrej Zapletal, Alexander Wild, Jan Jacques Michiels, Zwi Berneman, Jan Blatny, Angelika Batorova, Tatiana Prigancova, Miroslav Penka, Alain Gadisseur
Publikováno v:
TH Open, Vol 06, Iss 04, Pp e335-e346 (2022)
Background von Willebrand disease (VWD) is a genetic bleeding disorder caused by defects of von Willebrand factor (VWF), quantitative (type 1 and 3) or qualitative (type 2). The laboratory phenotyping is heterogenic making diagnosis difficult. Object
Externí odkaz:
https://doaj.org/article/75dd3755ee8443b3a845469109e1de0d
Autor:
Bert Heyrman, Stef Meers, Ann De Becker, Kristien Wouters, Achiel Van Hoof, Ann Van De Velde, Carlos Graux, Dominiek Mazure, Dominik Selleslag, Helena Maes, Jan Lemmens, Marielle Beckers, Dimitri Breems, Sélim Sid, Zwi Berneman, Sébastien Anguille
Publikováno v:
Cancers, Vol 15, Iss 13, p 3296 (2023)
Patients with myelodysplastic syndromes suffer from an impaired quality of life that is only partially explained by physical symptoms. In an observational study, we aimed to investigate the impact of current MDS treatments and the influence of diseas
Externí odkaz:
https://doaj.org/article/94d76e241f7146f786b83cc82691edc7
Autor:
Maarten Versteven, Donovan Flumens, Diana Campillo-Davó, Hans De Reu, Laura Van Bruggen, Stefanie Peeters, Viggo Van Tendeloo, Zwi Berneman, Harry Dolstra, Sébastien Anguille, Willemijn Hobo, Evelien Smits, Eva Lion
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Dendritic cell (DC) vaccines have proven to be a valuable tool in cancer immune therapy. With several DC vaccines being currently tested in clinical trials, knowledge about their therapeutic value has been significantly increased in the past decade.
Externí odkaz:
https://doaj.org/article/e0e0883d60f5415c9f97216c8a1d9417
Autor:
Megha Meena, Robin Vandormael, Maxime De Laere, Isabel Pintelon, Zwi Berneman, Regan Watts, Nathalie Cools
Publikováno v:
Brain Sciences, Vol 12, Iss 10, p 1293 (2022)
To study the biodistribution of new chemical and biological entities, an in vitro model of the blood–brain barrier (BBB) may become an essential tool during early phases of drug discovery. Here, we present a proof-of-concept of an in-house designed
Externí odkaz:
https://doaj.org/article/db8343db95c6477fbc50bf7c014533f1
Autor:
Gizem Oner, Sevilay Altintas, Zafer Canturk, Wiebren Tjalma, Christophe Van Berckelaer, Glenn Broeckx, Karen Zwaenepoel, Maria Tholhuijsen, Yannick Verhoeven, Zwi Berneman, Marc Peeters, Patrick Pauwels, Peter A van Dam
Publikováno v:
Cancer Treatment and Research Communications, Vol 25, Iss , Pp 100207- (2020)
Background: : Although hormone receptor positive/HER2-negative (HR +/HER2-) breast cancer is the most diagnosed breast cancer type, the immunologic aspects HR positive breast cancer (BC) has been neglected until recently. The purpose of this paper is
Externí odkaz:
https://doaj.org/article/9d4f83d0ae5f4732834520ae8907a941
Autor:
Fien H. R. De Winter, An Hotterbeekx, Manon T. Huizing, Angelina Konnova, Erik Fransen, Bart’s Jongers, Ravi Kumar Jairam, Vincent Van averbeke, Pieter Moons, Ella Roelant, Debbie Le Blon, Wim Vanden Berghe, Annelies Janssens, Willem Lybaert, Lieselot Croes, Christof Vulsteke, Surbhi Malhotra-Kumar, Herman Goossens, Zwi Berneman, Marc Peeters, Peter A. van Dam, Samir Kumar-Singh
Publikováno v:
Cancers, Vol 13, Iss 22, p 5718 (2021)
Cytokines, chemokines, and (angiogenic) growth factors (CCGs) have been shown to play an intricate role in the progression of both solid and haematological malignancies. Recent studies have shown that SARS-CoV-2 infection leads to a worse outcome in
Externí odkaz:
https://doaj.org/article/62d8aa4837a8463481aa74162ede7e63