Výsledky vyhledávání - "Zweckberger, K."

Neurological outcome following spinal intramedullary ependymoma ablation – a single centre experience

Autor: Alhalabi, OT, Landré, V, Zweckberger, K, Younsi, A, Unterberg, AW

Publikováno v: 73. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Griechischen Gesellschaft für Neurochirurgie; 20220529-20220601; Köln; DOCV235 /20220525/

Objective: Spinal intramedullary ependymomas represent a well-defined tumor entity usually warranting surgical resection. The perioperative morbidity and mortality, together with the oncological and neurological outcome of affected patients are seldo

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Reprogramming of astrocytes to neuronal precursor cells using lentiviral vectors for the potential treatment of CNS injuries

Autor: Schnaubelt, A, Zhou, X, Zheng, G, Wang, H, Hatami, M, Skutella, T, Unterberg, AW, Zweckberger, K, Younsi, A

Objective: The main drivers for persisting neurological symptoms after CNS injury are secondary pathophysiological changes, such as astrogliosis and glial scarring, inhibiting axonal regeneration and functional recovery. Thus, targeting the astroglia

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Application of Sonic Hedgehog in the acute phase after experimental spinal cord injury improves functional recovery and attenuates the inflammatory response

Autor: Tail, M, Zhang, H, Zheng, G, Hatami, M, Skutella, T, Unterberg, AW, Zweckberger, K, Younsi, A

Objective: Although Sonic Hedgehog (Shh) has been extensively researched on its effects in early neurogenesis and brain development since its discovery in 1980, its recently described crucial neuroprotective effects implicate important underlying mec

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Inflammatory changes in the hippocampus after experimental traumatic brain injury in a rat model

Autor: Große, K, Grutza, M, Walter, J, Heene, S, Zheng, G, Skutella, T, Unterberg, AW, Zweckberger, K, Younsi, A

Objective: Traumatic brain injury (TBI) is a leading cause of death worldwide. After the primary injury, a cascade of secondary injury processes is initiated, including a complex inflammatory reaction. As a critical and vulnerable brain region, the h

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Substance P is associated with early secondary injury processes after traumatic spinal cord injury

Autor: Wieckhusen, C, Heene, S, Zheng, G, Wang, H, Alhalabi, OT, Skutella, T, Unterberg, AW, Zweckberger, K, Younsi, A

Objective: Traumatic spinal cord injury (tSCI) is a devastating event, often associated with lifelong disability. Secondary to the primary injury, a cascade of secondary injury processes including blood-spinal cord barrier (BSCB) disintegration and n

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The S-Score is a tool for early prediction of neurological outcome in patients with aneurysmatic subarachnoid haemorrhage

Autor: Grutza, M, Walter, J, Unterberg, AW, Zweckberger, K

Objective: Aneurysmatic subarachnoid hemorrhage (aSAH) is frequently associated with a prolonged stay on the intensive care unit (ICU) and poor prognosis, which generates the need of early predictors of clinical course and functional outcome in order

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