Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Zvonko, Milicevic"'
Autor:
Richard Aarnio, Anna Kirjavainen, Johan Rajander, Sarita Forsback, Kari Kalliokoski, Pirjo Nuutila, Zvonko Milicevic, Tamer Coskun, Axel Haupt, Iina Laitinen, Merja Haaparanta-Solin
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Background Fatty acid uptake can be measured using PET and 14-(R,S)‐[18F]fluoro‐6‐thia‐heptadecanoic acid ([18F]FTHA). However, the relatively rapid rate of [18F]FTHA metabolism significantly affects kinetic modeling of tissue uptake
Externí odkaz:
https://doaj.org/article/431ec5815c0a4c829a4b8d52c133bc9b
Autor:
Jill Carlton, Frans Pouwer, Alan Brennan, Stephanie A Amiel, Pratik Choudhary, Simon Heller, Bastiaan E de Galan, Jane Speight, Ulrik Pedersen-Bjergaard, Giovanni Sparacino, Helen Colhoun, Christel Hendrieckx, Rory McCrimmon, Stephanie Amiel, Mark Evans, Eric Renard, Mark Ibberson, Rory J McCrimmon, Sean Sullivan, Stephen Gough, Hannah Chatwin, Melanie Broadley, Uffe Søholm, Ohad Cohen, Søren E Skovlund, Cees Tack, Bastiaan de Galan, Thomas Pieber, Julia Mader, Bernard Thorens, Jakob Haardt, Zvonko Milicevic, Mahmood Kazemi, Sanjoy Dutta, Dominique Robert, Wendy Wolf
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 10, Iss 4 (2022)
Introduction The aim of this study was to determine the psychometric properties of the 12-Item Hypoglycemia Impact Profile (HIP12), a brief measure of the impact of hypoglycemia on quality of life (QoL) among adults with type 1 (T1D) or type 2 diabet
Externí odkaz:
https://doaj.org/article/8065d6a74d4649e09328bccd4acc7a5b
Autor:
Tim Heise, J. Hans DeVries, Shweta Urva, Jing Li, Edward J. Pratt, Melissa K. Thomas, Kieren J. Mather, Chrisanthi A. Karanikas, Julia Dunn, Axel Haupt, Zvonko Milicevic, Tamer Coskun
Publikováno v:
Diabetes Care. 46:998-1004
OBJECTIVE To evaluate the effects of tirzepatide on body composition, appetite, and energy intake to address the potential mechanisms involved in body weight loss with tirzepatide. RESEARCH DESIGN AND METHODS In a secondary analysis of a randomized,
Autor:
Shweta, Urva, Tamer, Coskun, Mei Teng, Loh, Yu, Du, Melissa K, Thomas, Sirel, Gurbuz, Axel, Haupt, Charles T, Benson, Martha, Hernandez-Illas, David A, D'Alessio, Zvonko, Milicevic
Publikováno v:
The Lancet. 400:1869-1881
Treating hyperglycaemia and obesity in individuals with type 2 diabetes using multi-receptor agonists can improve short-term and long-term outcomes. LY3437943 is a single peptide with agonist activity for glucagon, glucose-dependent insulinotropic po
Autor:
Tim Heise, J Hans DeVries, Shweta Urva, Jing Li, Edward John Pratt, Melissa K. Thomas, Kieren Mather, Julia Dunn, Axel Haupt, Zvonko Milicevic, Tamer Coskun
Publikováno v:
Diabetologie und Stoffwechsel.
Autor:
Tamer Coskun, Zvonko Milicevic, Axel Haupt, Julia Dunn, Chrisanthi A. Karanikas, Kieren J. Mather, Melissa K. Thomas, Edward J. Pratt, Jing Li, Shweta Urva, J Hans DeVries, Tim Heise
OBJECTIVE: To evaluate effects of tirzepatide on body composition, appetite and energy intake to address the potential mechanisms involved in body weight loss with tirzepatide. RESEARCH DESIGN AND METHODS: In a secondary analysis of a randomized, dou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8174afe34e453bf3a6daeece5fa35b3d
https://doi.org/10.2337/figshare.21984596.v1
https://doi.org/10.2337/figshare.21984596.v1
Autor:
TIM HEISE, J. HANS DE VRIES, TAMER COSKUN, SHWETA URVA, JING LI, EDWARD J. PRATT, MELISSA K. THOMAS, KIEREN J. MATHER, JULIA P. DUNN, AXEL HAUPT, ZVONKO MILICEVIC
Publikováno v:
Diabetes. 71
Tirzepatide (TZP) , a dual GIP and GLP-1 receptor agonist (RA) has shown superior improvement in glycemic control and body weight than selective GLP-1 RA. Rodent models indicate that GIP RA augments GLP-1 RA induced food intake suppression and causes
Autor:
ANDREA MARI, JING LI, SHWETA URVA, TIM HEISE, J. HANS DE VRIES, EDWARD J. PRATT, ROBERT J. HEINE, MELISSA K. THOMAS, ZVONKO MILICEVIC, KIEREN J. MATHER
Publikováno v:
Diabetes. 71
We investigated the effect of tirzepatide (TZP) 15 mg (novel GIP-GLP-1 dual receptor agonist) , placebo and semaglutide 1 mg (SEMA) on beta-cell function using euglycaemic and hyperglycemic glucose clamps (EGC, HGC) and Mixed Meal Tolerance Tests (MM
Autor:
SHWETA URVA, MEI TENG LOH, TAMER COSKUN, YU DU, CHARLES BENSON, CORINA LOGHIN, AXEL HAUPT, ZVONKO MILICEVIC
Publikováno v:
Diabetes. 71
Multi-receptor incretin agonists are being developed for several metabolic disorders. LY is an investigational triple agonist with potent activity on glucose-dependent insulinotropic polypeptide (GIP) , glucagon-like polypeptide-1 (GLP-1) , and gluca
Autor:
Tim, Heise, Andrea, Mari, J Hans, DeVries, Shweta, Urva, Jing, Li, Edward John, Pratt, Tamer, Coskun, Melissa K, Thomas, Kieren J, Mather, Axel, Haupt, Zvonko, Milicevic
Publikováno v:
Lancet. Diabetes and endocrinology, 10(6), 418-429. Elsevier BV
Background: Tirzepatide, a dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor agonist, shows a remarkable ability to lower blood glucose, enabling many patients with long-standing type 2 diabetes to achieve normoglycaemia. We aime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114333746341eaa7eb406318786f093d
https://pure.amc.nl/en/publications/effects-of-subcutaneous-tirzepatide-versus-placebo-or-semaglutide-on-pancreatic-islet-function-and-insulin-sensitivity-in-adults-with-type-2-diabetes(7eebb311-02b1-40db-b66f-d99628ecb9b1).html
https://pure.amc.nl/en/publications/effects-of-subcutaneous-tirzepatide-versus-placebo-or-semaglutide-on-pancreatic-islet-function-and-insulin-sensitivity-in-adults-with-type-2-diabetes(7eebb311-02b1-40db-b66f-d99628ecb9b1).html