Výsledky vyhledávání - "Zvonimir Grahovac"

Intraarterial Mitomycin-C for Recurrent Brain Metastases

Autor: Zvonimir Grahovac, Herman Hugenholtz, Cyril Danjoux, David J. Stewart, Michael D. Riding, Jean A. Maroun, Brien Benoit, Neville Russell, M. T. Richard

Publikováno v: American Journal of Clinical Oncology. 10:432-436

Fifteen consenting patients with brain metastases recurrent after cranial irradiation were treated with intraarterial mitomycin-C, 15 mg/m2, administered in a total final volume of 100 ml 0.45% saline over 20 min through a transfemoral catheter with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab26da40e31650874f3f9e604876d4d6
https://doi.org/10.1097/00000421-198710000-00013

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Treatment of malignant gliomas in adults with BCNU plus metronidazole

Autor: David J. Stewart, Brien Benoit, Michael T. Richard, Herman Hugenholtz, Jean Dennery, Neville Russell, Eric Peterson, Zvonimir Grahovac, Garry Belanger, Jean A. Maroun, Vincent Young

Publikováno v: Journal of Neuro-Oncology. 2:53-58

Twenty-six adult patients with astrocytomas were treated with BCNU (1,3-bis(2-chloroethyl)-1-nitrosourea) 180-240 mg/m2 I.V. every 6-9 weeks, with metronidazole 1.5 g/m2 p.o. 12 h and 1 h before BCNU and again 6 h and 24 h after BCNU. Of twenty-two e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb35ec23b08d2ad15bc500bf76305f0a
https://doi.org/10.1007/bf00165158

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Intracarotid Chemotherapy with a Combination of 1,3-Bis(2-chloroethyl)-1-nitrosourea (BCNU), cis-Diaminedichloroplatinum (Cisplatin), and 4'-O-Demethyl-1-O-(4,6-O-2-thenylidene-β-D-glucopyranosyl)epipodophyllotoxin (VM-26) in the Treatment of Primary and Metastatic Brain Tumors

Autor: David J. Stewart, Zvonimir Grahovac, Brien Benoit, David Addison, Michael T. Richard, Jean Dennery, Herman Hugenholtz, Neville Russell, Eric Peterson, Jean A. Maroun, Ted Vandenberg, Harry S. Hopkins

Publikováno v: Neurosurgery. 15:828-833

Thirty-seven patients with intracranial primary or metastatic tumors were treated with an intraarterial combination of BCNU, cisplatin, and VM-26 to determine the efficacy, toxicity, and maximal tolerated doses for the combination. A transfemoral flu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7999c55e0ebe1472c4396753ad955c3
https://doi.org/10.1097/00006123-198412000-00010

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Phase II study of novantrone (mitroxantrone hydrochloride) in adults with grade III-IV astrocytomas

Autor: Jean A. Maroun, Zvonimir Grahovac, Herman Hugenholtz, David J. Stewart, M. T. Richard, André Girard, Neville Russell, Brien Benoit, James F. Nabwangu

Publikováno v: Biology of Brain Tumour ISBN: 9781461294153

Sixteen patients with malignant gliomas were trated with mitoxantrone 16 mg/m2 intravenously. One patient responded. Myelosuppression was dose-limiting but tolerable. Mitoxantrone has minimal activity against gliomas.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7b4536ace00c051c81e97d30bea6eaa3
https://doi.org/10.1007/978-1-4613-2297-9_55

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Cisplatin, arabinofuranosyl cytosine, and caffeine before radiation for glioblastomas

Autor: Eric W. Peterson, Jean A. Maroun, James F. Nabwangu, André Girard, Garry Belanger, Brien Benoit, Zvonimir Grahovac, Harry S. Hopkins, Wanda Assang, M. T. Richard, Jean Dennery, Herman Hugenholtz, David J. Stewart, Neville Russell

Publikováno v: Biology of Brain Tumour ISBN: 9781461294153

The combination of cisplatin 100 mg/m2 IV followed in 2–4 hours by arabinofuranosyl cytosine (ara-c) 3000 mg/m2, followed immediately by caffeine 300 mg/m2 was found to be tolerable, with myelosuppression limiting the dose of ara-c and seizures lim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e7aebc66710a73b2a3670c3bbb5f493b
https://doi.org/10.1007/978-1-4613-2297-9_52

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Phase I study of intraarterial mitomycin-c for recurrent intracerebral tumors

Autor: Brian Luke, Brien Benoit, Herman Hugenholtz, David J. Stewart, Jean Dennery, Eric Peterson, Enrique C. G. Ventureyra, Jean A. Maroun, Neville Russell, Zvonimir Grahovac, Michael T. Richard, Harry S. Hopkins, André Girard

Publikováno v: Biology of Brain Tumour ISBN: 9781461294153

Seventeen patients with intracerebral neoplasms were treated with intra-arterial mitomycin-c 7.5–18 mg/m2 at 6–9 week intervals. Most were heavily pretreated. Three of 8 evaluable patients with brain metastases, a single patient with a primitive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b0e7461692b55c031f17d391106695e
https://doi.org/10.1007/978-1-4613-2297-9_65

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Phase I study of intracarotid PCNU

Autor: Neville A. Russel, Zvonimir Grahovac, Herman Hugenholtz, Sunil Gupta, Brien C. Benoit, M. T. Richard, Harry S. Hopkins, David J. Stewart, Liliane Locke, Jean A. Maroun

Publikováno v: Journal of neuro-oncology. 5(3)

A phase I study of the intracarotid administration of PCNU was conducted in patients with intracerebral tumors recurring after cranial radiation. Seventeen patients were treated including 16 with recurrent gliomas or glioblastomas and 1 with recurren

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec92e2076d3d5018268e39f1d5100a34
https://pubmed.ncbi.nlm.nih.gov/3681387

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Cyclophosphamide, Adriamycin, vincristine, and dexamethasone in the treatment of bulky central nervous system lymphoma

Autor: Zvonimir Grahovac, Garry Belanger, David J. Stewart, Edward Atack, Jean A. Maroun, M. T. Richard, Jean Dennery, Libni Eapen, André Girard, Neville Russell

Publikováno v: Biology of Brain Tumour ISBN: 9781461294153

Six patients with bulky central nervous system lymphomas (5 primary and 1 metastatic) were treated with a combination of cyclophosphamide, Adriamycin, vincristine, and dexamethasone IV prior to receiving cranial irradiation. There was one early death

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5302ff89e87a7c90b48beb40c93862a4
https://doi.org/10.1007/978-1-4613-2297-9_59

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Combined intraarterial and systemic chemotherapy for intracerebral tumors

Autor: Brien Benoit, Zvonimir Grahovac, Herman Hugenholtz, M. T. Richard, Neville Russell, David J. Stewart

Publikováno v: Neurosurgery. 21:207

Twenty-six patients with intracerebral tumors (predominantly gliomas) were treated with intraarterial BCNU, VM-26, and cisplatin combined with the systemic administration of VM-26, methotrexate, vincristine, bleomycin, and procarbazine. Oral glycerol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aeda8c31d3d7a59c771ef4a8bae9bed
https://doi.org/10.1097/00006123-198708000-00013

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