Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Zvi Grossman"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
The systemic bio-organization of humans and other mammals is essentially “preprogrammed”, and the basic interacting units, the cells, can be crudely mapped into discrete sets of developmental lineages and maturation states. Over several decades,
Externí odkaz:
https://doaj.org/article/76926099661042109441fdeb334b0a51
Autor:
Zvi Grossman
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Most mathematical models that describe the individual or collective actions of cells aim at creating faithful representations of limited sets of data in a self-consistent manner. Consistency with relevant physiological rules pertaining to the greater
Externí odkaz:
https://doaj.org/article/be956908a8f4423f9f7208d86c049ed8
Autor:
Souheil-Antoine Younes, George Punkosdy, Stephane Caucheteux, Tao Chen, Zvi Grossman, William E Paul
Publikováno v:
PLoS Biology, Vol 9, Iss 10, p e1001171 (2011)
Memory phenotype (CD44(bright), CD25(negative)) CD4 spleen and lymph node T cells (MP cells) proliferate rapidly in normal or germ-free donors, with BrdU uptake rates of 6% to 10% per day and Ki-67 positivity of 18% to 35%. The rapid proliferation of
Externí odkaz:
https://doaj.org/article/15ccd62a1e97471dae43545209843a23
Autor:
Felix Tretter, Eva M. J. Peters, Joachim Sturmberg, Jeanette Bennett, Eberhard Voit, Johannes W. Dietrich, Gary Smith, Wolfram Weckwerth, Zvi Grossman, Olaf Wolkenhauer, James A. Marcum
Publikováno v:
Journal of Evaluation in Clinical Practice. 29:415-429
Is data-driven analysis sufficient for understanding the COVID-19 pandemic and for justifying public health regulations? In this paper, we argue that such analysis is insufficient. Rather what is needed is the identification and implementation of ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1a0b7119f2edcc8b83f7971eaddf1b
https://doi.org/10.1111/jep.13772
https://doi.org/10.1111/jep.13772
Autor:
Hagit Alon, Leonid Margolis, Nevil J. Singh, Zvi Grossman, Martin Meier-Schellersheim, Zehava Grossman, Takeshi Kawabe, Francesco R. Simonetti, Gennady Bocharov, Daniel C. Douek, Steven G. Deeks, Michael M. Lederman, Frank Maldarelli, Nicolas Chomont, Ana E. Sousa
Publikováno v:
Trends in Immunology. 41:466-480
Latent HIV-1 persists indefinitely during antiretroviral therapy (ART) as an integrated silent genome in long-lived memory CD4+ T cells. In untreated infections, immune activation increases the turnover of intrinsically long-lived provirus-containing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d3c7825c8baa0e9f4b7e0a430bce84
https://doi.org/10.1016/j.it.2020.04.003
https://doi.org/10.1016/j.it.2020.04.003
Autor:
Eugene E. Tyrtyshnikov, Zvi Grossman, Valeriya V. Zheltkova, Dmitry A. Zheltkov, Gennady Bocharov
Publikováno v:
Journal of Inverse and Ill-posed Problems. 26:51-66
The development of efficient computational tools for data assimilation and analysis using multi-parameter models is one of the major issues in systems immunology. The mathematical description of the immune processes across different scales calls for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5babbd2ad4cb766165ae86680237480c
https://doi.org/10.1515/jiip-2016-0083
https://doi.org/10.1515/jiip-2016-0083
Autor:
William E. Paul, Juan Quiel, Zvi Grossman, Stephane Caucheteux, Nevil J. Singh, Shlomo Z. Ben-Sasson, Arian Laurence, Gennady Bocharov
Publikováno v:
Proceedings of the National Academy of Sciences. 108:3312-3317
Antigen-driven expansion of specific CD4 T cells diminishes, on a per cell basis, as infused cell number increases. There is a linear relation between log precursor number and log factor of expansion (FE), with a slope of ∼−0.5 over a range from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36e4f5551f157b9e47b009b027ec0d2d
https://doi.org/10.1073/pnas.1018525108
https://doi.org/10.1073/pnas.1018525108
Autor:
Zvi Grossman, Louis J. Picker
Publikováno v:
Current Opinion in HIV and AIDS. 3:380-386
Recent work in pathogenic simian immunodeficiency (SIV) infection of Asian macaques and in natural, nonpathogenic SIV infections of African nonhuman primate species has demonstrated that persistent activation has profound effects on CD4+ memory T-cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35cf0443647ff799b0c40f30bfa0c542
https://doi.org/10.1097/coh.0b013e3282fbaae6
https://doi.org/10.1097/coh.0b013e3282fbaae6
Autor:
Jason M. Brenchley, Jeffrey D. Lifson, Donald L. Sodora, Alfred W. Legasse, Martin Meier-Schellersheim, Afam A. Okoye, John B. Edgar, Michael Piatak, Shoko I. Hagen, Vernon C. Maino, Michael K. Axthelm, Shannon L. Planer, Joshua M. Walker, Richard Lum, Mukta Rohankhedkar, Louis J. Picker, Andrew W. Sylwester, Zvi Grossman, Daniel C. Douek
Publikováno v:
The Journal of Experimental Medicine
Primary simian immunodeficiency virus (SIV) infections of rhesus macaques result in the dramatic depletion of CD4(+) CCR5(+) effector-memory T (T(EM)) cells from extra-lymphoid effector sites, but in most infections, an increased rate of CD4(+) memor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c4655c593e018e3ee9a81c9d5c5294
https://doi.org/10.1084/jem.20070567
https://doi.org/10.1084/jem.20070567
Autor:
Lena H. Kalfayan, Anne Elen Kernaleguen, Lawrence J. Stern, Zvi Grossman, Rachid Boulassel, Jean-Pierre Routy, Bader Yassine-Diab, Souheil Antoine Younes, Thomas O. Cameron, Rafick Pierre Sekaly, Lydie Trautmann, Alain R. Dumont
Publikováno v:
The Journal of Immunology. 178:788-797
The impact of exposure to Ag on the development and maintenance of human CD4+ memory T cells in general and HIV infection in particular is partially understood. In this study, we measured HIV-specific CD4+ T cell proliferative responses against HIV p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e2432c30f5ee44d0edce9ea8bbdb8e2
https://doi.org/10.4049/jimmunol.178.2.788
https://doi.org/10.4049/jimmunol.178.2.788