Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Zvi Granot"'
Autor:
Heba Alkhatib, Ariel M. Rubinstein, Swetha Vasudevan, Efrat Flashner-Abramson, Shira Stefansky, Sangita Roy Chowdhury, Solomon Oguche, Tamar Peretz-Yablonsky, Avital Granit, Zvi Granot, Ittai Ben-Porath, Kim Sheva, Jon Feldman, Noa E. Cohen, Amichay Meirovitz, Nataly Kravchenko-Balasha
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-17 (2022)
Abstract Background Drug resistance continues to be a major limiting factor across diverse anti-cancer therapies. Contributing to the complexity of this challenge is cancer plasticity, in which one cancer subtype switches to another in response to tr
Externí odkaz:
https://doaj.org/article/1bfb8d0fe62b40729734ee0a48f29698
Autor:
Sandra Völs, Naomi Kaisar-Iluz, Merav E. Shaul, Arik Ryvkin, Haim Ashkenazy, Avishag Yehuda, Ronza Atamneh, Adina Heinberg, Meital Ben-David-Naim, Menucha Nadav, Shira Hirsch, Vera Mitesser, Seth J. Salpeter, Ron Dzikowski, Zvi Hayouka, Jonathan M. Gershoni, Zvi G. Fridlender, Zvi Granot
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Neutrophils play critical roles in a broad spectrum of clinical conditions. Accordingly, manipulation of neutrophil function may provide a powerful immunotherapeutic approach. However, due to neutrophils characteristic short half-life and their large
Externí odkaz:
https://doaj.org/article/215320c31c0b4edbb720d0fc23fc1890
Autor:
Ofer Regev, Marina Kizner, Francesco Roncato, Maya Dadiani, Massimo Saini, Francesc Castro-Giner, Olga Yajuk, Stav Kozlovski, Nehora Levi, Yoseph Addadi, Ofra Golani, Shifra Ben-Dor, Zvi Granot, Nicola Aceto, Ronen Alon
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Breast tumors and their derived circulating cancer cells express the leukocyte β2 integrin ligand Intercellular adhesion molecule 1 (ICAM-1). We found that elevated ICAM-1 expression in breast cancer cells results in a favorable outcome and prolonge
Externí odkaz:
https://doaj.org/article/d9e88f61fbda4bd2a272841d63826b3e
Autor:
Maya Braun, Shachar Shoshani, Joana Teixeira, Anna Mellul Shtern, Maya Miller, Zvi Granot, Sylvia E.J. Fischer, Susana M.D. A. Garcia, Yuval Tabach
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104246- (2022)
Summary: Nucleotide repeat expansions are a hallmark of over 40 neurodegenerative diseases and cause RNA toxicity and multisystemic symptoms that worsen with age. Through an unclear mechanism, RNA toxicity can trigger severe disease manifestation in
Externí odkaz:
https://doaj.org/article/d676fb5f1b654b059ca467422dae29ee
Autor:
Lishay Parhi, Tamar Alon-Maimon, Asaf Sol, Deborah Nejman, Amjad Shhadeh, Tanya Fainsod-Levi, Olga Yajuk, Batya Isaacson, Jawad Abed, Naseem Maalouf, Aviram Nissan, Judith Sandbank, Einav Yehuda-Shnaidman, Falk Ponath, Jörg Vogel, Ofer Mandelboim, Zvi Granot, Ravid Straussman, Gilad Bachrach
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
High levels of Fusobacterium nucleatum have been associated with poor overall survival in patients with colorectal and esophageal cancer. Here, the authors show that F. nucleatum is abundant in breast cancer samples and that the colonization by F. nu
Externí odkaz:
https://doaj.org/article/776f0ce45a884e0eb485ae59e2c301df
Publikováno v:
Biomedicines, Vol 10, Iss 4, p 908 (2022)
Neutrophil-mediated cytotoxicity toward tumor cells requires cell contact and is mediated by hydrogen peroxide. We have recently shown that Cathepsin G expressed on the neutrophil surface interacts with tumor RAGE, and this interaction facilitates ne
Externí odkaz:
https://doaj.org/article/1dc2fcfd4669421ab28028fa8141ffa5
Autor:
Ronit Vogt Sionov, Tanya Fainsod-Levi, Tamir Zelter, Lola Polyansky, Christine T. Pham, Zvi Granot
Publikováno v:
OncoImmunology, Vol 8, Iss 9 (2019)
Neutrophils are a heterogeneous population of myeloid cells which may either promote or hinder tumor growth and progression. Anti-tumor neutrophils have the capacity to kill tumor cells in a contact-dependent manner. However, the molecular mechanisms
Externí odkaz:
https://doaj.org/article/6d8c427b46264aa5a87564103438a9ce
Autor:
Tanya Fainsod-Levi, Maya Gershkovitz, Sandra Völs, Saran Kumar, Saleh Khawaled, Jitka Y. Sagiv, Ronit V. Sionov, Myriam Grunewald, Eli Keshet, Zvi Granot
Publikováno v:
Cell Reports, Vol 21, Iss 9, Pp 2384-2392 (2017)
Preexisting diabetes is a risk factor for the development of multiple types of cancer. Additionally, diabetic patients face a poorer prognosis when diagnosed with cancer. To gain insight into the effects of hyperglycemia, a hallmark of diabetes, on t
Externí odkaz:
https://doaj.org/article/d0ad1cd2d5bb404d99dce8614c28cc31
Publikováno v:
Cells, Vol 10, Iss 6, p 1510 (2021)
The PD-L1/PD-1 axis mediates immune tolerance and promotes tumor growth and progression via the inhibition of anti-tumor immunity. Blocking the interaction between PD-L1 and PD-1 was clinically shown to be beneficial in maintaining the anti-tumor fun
Externí odkaz:
https://doaj.org/article/2b0635ce9570461c9d58a0edceb84188
Autor:
Batya Isaacson, Tehila Hadad, Ariella Glasner, Chamutal Gur, Zvi Granot, Gilad Bachrach, Ofer Mandelboim
Publikováno v:
Cell Reports, Vol 20, Iss 1, Pp 40-47 (2017)
Urinary tract infection (UTI) is the most common type of bacterial infection in humans. Fifty percent of all women will experience at least one UTI in their lifetime, with uropathogenic Escherichia coli (UPEC) accounting for 80% of reported cases. UT
Externí odkaz:
https://doaj.org/article/a982160ad1654cd4a7a5bcd083fdc035